5EWZ
Small-molecule stabilization of the 14-3-3/Gab2 PPI interface
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | 14-3-3 protein zeta/delta | polymer | 230 | 26316.8 | 2 | UniProt (P63104) Pfam (PF00244) | Homo sapiens (Human) | Protein kinase C inhibitor protein 1,KCIP-1 |
| 2 | C (C) | GRB2-associated-binding protein 2 | polymer | 9 | 1137.3 | 1 | UniProt (Q9UQC2) | Homo sapiens | GRB2-associated binder 2,Growth factor receptor bound protein 2-associated protein 2,pp100 |
| 3 | D (D) | GRB2-associated-binding protein 2 | polymer | 6 | 734.7 | 1 | UniProt (Q9UQC2) | Homo sapiens | GRB2-associated binder 2,Growth factor receptor bound protein 2-associated protein 2,pp100 |
| 4 | E, F (A, B) | BENZOIC ACID | non-polymer | 122.1 | 2 | Chemie (BEZ) | |||
| 5 | G, H, I, J (A, B, C, D) | water | water | 18.0 | 328 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 54505.5 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 244.2 | |
| All* | Total formula weight | 54749.7 |
