4QLI

A novel phospho-switch in the linker region of the snail zinc finger protein which regulates 14-3-3 association, DNA binding and epithelial-mesenchymal differentiation

Summary for 4QLI

Entry DOI	10.2210/pdb4qli/pdb
Related	4IEA 4JDD 4N7G
Descriptor	14-3-3 protein sigma, Zinc finger protein SNAI1, MAGNESIUM ION, ... (5 entities in total)
Functional Keywords	14-3-3, adapter protein, protein-protein interaction, signaling protein
Biological source	Homo sapiens (human) More
Cellular location	Cytoplasm: P31947 Nucleus: O95863
Total number of polymer chains	2
Total formula weight	27420.41
Authors	Bier, D.,Ottmann, C. (deposition date: 2014-06-12, release date: 2015-06-17)
Primary citation	Liu, Y.,Prokop, J.W.,Peng, H.,Karar, J.,White, D.,Hou, Z.,Qin, Y.S.,Bier, D.,Ottmann, C.,Waxman, S.,Halazonetis, T.D.,Rauscher III, F.J. A novel phospho-switch in the linker region of the snail zinc finger protein which regulates 14-3-3 association, DNA binding and epithelial-mesenchymal differentiation To be Published,
Experimental method	X-RAY DIFFRACTION (1.45 Å)

Structure validation