4QLI

A novel phospho-switch in the linker region of the snail zinc finger protein which regulates 14-3-3 association, DNA binding and epithelial-mesenchymal differentiation

Summary for 4QLI

• Entry DOI: 10.2210/pdb4qli/pdb
• Related: 4IEA 4JDD 4N7G
• Descriptor: 14-3-3 protein sigma, Zinc finger protein SNAI1, MAGNESIUM ION, ... (5 entities in total)
• Functional Keywords: 14-3-3, adapter protein, protein-protein interaction, signaling protein
• Biological source: Homo sapiens (human); More
• Cellular location: Cytoplasm: P31947; Nucleus: O95863
• Total number of polymer chains: 2
• Total formula weight: 27420.41

Authors

Bier, D.,Ottmann, C. (deposition date: 2014-06-12, release date: 2015-06-17, Last modification date: 2024-11-27)

• Primary citation: Liu, Y.,Prokop, J.W.,Peng, H.,Karar, J.,White, D.,Hou, Z.,Qin, Y.S.,Bier, D.,Ottmann, C.,Waxman, S.,Halazonetis, T.D.,Rauscher III, F.J.; A novel phospho-switch in the linker region of the snail zinc finger protein which regulates 14-3-3 association, DNA binding and epithelial-mesenchymal differentiation; To be Published,

Experimental method

X-RAY DIFFRACTION (1.45 Å)