4QLI
A novel phospho-switch in the linker region of the snail zinc finger protein which regulates 14-3-3 association, DNA binding and epithelial-mesenchymal differentiation
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | 14-3-3 protein sigma | polymer | 236 | 26542.0 | 1 | UniProt (P31947) Pfam (PF00244) | Homo sapiens (human) | Epithelial cell marker protein 1, Stratifin |
| 2 | B (B) | Zinc finger protein SNAI1 | polymer | 6 | 737.7 | 1 | UniProt (O95863) | Homo sapiens | Protein snail homolog 1, Protein sna |
| 3 | C, D (A) | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) | |||
| 4 | E (A) | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 5 | F, G (A, B) | water | water | 18.0 | 186 | Chemie (HOH) |
Sequence modifications
A: 1 - 231 (UniProt: P31947)
| PDB | External Database | Details |
|---|---|---|
| Gly -4 | - | EXPRESSION TAG |
| Ala -3 | - | EXPRESSION TAG |
| Met -2 | - | EXPRESSION TAG |
| Gly -1 | - | EXPRESSION TAG |
| Ser 0 | - | EXPRESSION TAG |
| Leu 175 | Asn 175 | CONFLICT |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 27279.7 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 140.7 | |
| All* | Total formula weight | 27420.4 |
