6FNU
Structure of S. cerevisiae Methylenetetrahydrofolate reductase 1, catalytic domain
Summary for 6FNU
Entry DOI | 10.2210/pdb6fnu/pdb |
Descriptor | Methylenetetrahydrofolate reductase 1, FLAVIN-ADENINE DINUCLEOTIDE (3 entities in total) |
Functional Keywords | reductase, one carbon metabolism, tim barrel, folate metabolism, structural genomics, structural genomics consortium, sgc, oxidoreductase |
Biological source | Saccharomyces cerevisiae (Baker's yeast) |
Total number of polymer chains | 1 |
Total formula weight | 35580.30 |
Authors | Kopec, J.,Rembeza, E.,Bezerra, G.A.,Newman, J.,Bountra, C.,Froese, D.S.,Baumgartner, M.,Yue, W.W.,Structural Genomics Consortium (SGC) (deposition date: 2018-02-05, release date: 2018-03-07, Last modification date: 2024-05-08) |
Primary citation | Froese, D.S.,Kopec, J.,Rembeza, E.,Bezerra, G.A.,Oberholzer, A.E.,Suormala, T.,Lutz, S.,Chalk, R.,Borkowska, O.,Baumgartner, M.R.,Yue, W.W. Structural basis for the regulation of human 5,10-methylenetetrahydrofolate reductase by phosphorylation and S-adenosylmethionine inhibition. Nat Commun, 9:2261-2261, 2018 Cited by PubMed: 29891918DOI: 10.1038/s41467-018-04735-2 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.56 Å) |
Structure validation
Download full validation report