Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004489 | molecular_function | methylenetetrahydrofolate reductase (NAD(P)H) activity |
| A | 0006555 | biological_process | methionine metabolic process |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 28 |
| Details | binding site for residue FAD A 701 |
| Chain | Residue |
| A | THR49 |
| A | TYR129 |
| A | ALA130 |
| A | ALA150 |
| A | TYR152 |
| A | HIS156 |
| A | ASP171 |
| A | TYR174 |
| A | GLU177 |
| A | LYS178 |
| A | ILE187 |
| A | TRP50 |
| A | GLN189 |
| A | TYR286 |
| A | HOH831 |
| A | HOH832 |
| A | HOH842 |
| A | HOH872 |
| A | HOH881 |
| A | HOH894 |
| A | HOH923 |
| A | ALA52 |
| A | HIS78 |
| A | LEU105 |
| A | LEU107 |
| A | ARG108 |
| A | GLY109 |
| A | TRP117 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | ACT_SITE: Proton donor/acceptor => ECO:0000250 |
| Chain | Residue | Details |
| A | GLU18 | |
| site_id | SWS_FT_FI2 |
| Number of Residues | 11 |
| Details | BINDING: BINDING => ECO:0000250 |
| Chain | Residue | Details |
| A | GLU18 | |
| A | GLN189 | |
| A | TYR286 | |
| A | THR49 | |
| A | HIS78 | |
| A | ARG108 | |
| A | ASP110 | |
| A | TYR129 | |
| A | TYR152 | |
| A | ASP171 | |
| A | LYS178 | |
| Chain | Residue | Details |
| A | SER120 | |
| A | SER301 | |
