PDB: 55616 件ウェブページステータス検索Chemie searchBIRD

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5CP6	Nucleosome Core Particle with Adducts from the Anticancer Compound, [(eta6-5,8,9,10-tetrahydroanthracene)Ru(ethylenediamine)Cl][PF6] 分子名称: (ethane6-5,8,9,10-tetrahydroanthracene)Ru(II)(ethylene-diamine)Cl, DNA (145-MER), Histone H2A, ... 著者 Ma, Z, Adhireksan, Z, Murray, B.S, Dyson, P.J, Davey, C.A. 登録日 2015-07-21 公開日 2016-06-01 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 An Organometallic Compound which Exhibits a DNA Topology-Dependent One-Stranded Intercalation Mode. Angew.Chem.Int.Ed.Engl., 55, 2016
4APW	Alp12 filament structure 分子名称: ALP12 著者 Popp, D, Narita, A, Lee, L.J, Ghoshdastider, U, Xue, B, Srinivasan, R, Balasubramanian, M.K, Tanaka, T, Robinson, R.C. 登録日 2012-04-06 公開日 2012-05-16 最終更新日 2024-05-08 実験手法 ELECTRON MICROSCOPY (19.700001 Å) 主引用文献 Novel Actin-Like Filament Structure from Clostridium Tetani. J.Biol.Chem., 287, 2012
3P8J	Y351S mutant of pentaerythritol tetranitrate reductase containing a bound acetate molecule 分子名称: ACETATE ION, FLAVIN MONONUCLEOTIDE, Pentaerythritol tetranitrate reductase 著者 Toogood, H.S, Scrutton, N.S. 登録日 2010-10-14 公開日 2011-04-06 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1 Å) 主引用文献 Active site modifications in pentaerythritol tetranitrate reductase can lead to improved product enantiopurity, decreased by-product formation and altered stereochemical outcome in reactions with a,b-unsaturated nitroolefins Catalysis Science and Technology, 2011
3P84	Y351A mutant of pentaerythritol tetranitrate reductase containing a bound acetate molecule 分子名称: ACETATE ION, FLAVIN MONONUCLEOTIDE, Pentaerythritol tetranitrate reductase 著者 Toogood, H.S, Scrutton, N.S. 登録日 2010-10-13 公開日 2011-04-06 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.1 Å) 主引用文献 Active site modifications in pentaerythritol tetranitrate reductase can lead to improved product enantiopurity, decreased by-product formation and altered stereochemical outcome in reactions with a,b-unsaturated nitroolefins Catalysis Science and Technology, 2011
3C07	Crystal structure of a TetR family transcriptional regulator from Streptomyces coelicolor A3(2) 分子名称: Putative tetR-family transcriptional regulator, SULFATE ION 著者 Tan, K, Xu, X, Zheng, H, Savchenko, A, Edwards, A.M, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) 登録日 2008-01-18 公開日 2008-02-05 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 The structure of a TetR family transcriptional regulator from Streptomyces coelicolor A3(2). To be Published
5CC9	L28F E.coli dihydrofolate reductase complexed with 5,10-dideazatetrahydrofolate and oxidized nicotinamide adenine dinucleotide phosphate 分子名称: 5,10-DIDEAZATETRAHYDROFOLIC ACID, Dihydrofolate reductase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE 著者 Oyen, D, Wright, P.E. 登録日 2015-07-01 公開日 2015-08-05 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.199 Å) 主引用文献 Cofactor-Mediated Conformational Dynamics Promote Product Release From Escherichia coli Dihydrofolate Reductase via an Allosteric Pathway. J.Am.Chem.Soc., 137, 2015
3V1S	Scaffold tailoring by a newly detected Pictet-Spenglerase ac-tivity of strictosidine synthase (STR1): from the common tryp-toline skeleton to the rare piperazino-indole framework 分子名称: 2-(1H-indol-1-yl)ethanamine, Strictosidine synthase 著者 Wu, F, Zhu, H, Sun, L, Rajendran, C, Wang, M, Ren, X, Panjikar, S, Cherkasov, A, Zou, H, Stoeckigt, J. 登録日 2011-12-10 公開日 2012-02-29 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.328 Å) 主引用文献 Scaffold Tailoring by a Newly Detected Pictet-Spenglerase Activity of Strictosidine Synthase: From the Common Tryptoline Skeleton to the Rare Piperazino-indole Framework J.Am.Chem.Soc., 134, 2012
4ME9	Crystal structure of a transcriptional regulator, TetR family (BCE_2991) from Bacillus cereus ATCC 10987 at 2.50 A resolution 分子名称: CHLORIDE ION, PHOSPHATE ION, Transcriptional regulator, ... 著者 Joint Center for Structural Genomics (JCSG) 登録日 2013-08-25 公開日 2013-09-25 最終更新日 2023-02-01 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Crystal structure of a transcriptional regulator, TetR family (BCE_2991) from Bacillus cereus ATCC 10987 at 2.50 A resolution To be published
5IYE	Comparison of X-ray crystal structures of a tetradecamer sequence d(CCCGGGTACCCGGG)2 at 1.7 resolution 分子名称: DNA (5'-D(*CP*CP*CP*GP*GP*GP*TP*AP*CP*CP*CP*GP*GP*G)-3'), ZINC ION 著者 Karthik, S, Thirugnanasambandam, A, Mandal, P.K, Gautham, N. 登録日 2016-03-24 公開日 2017-03-29 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.694 Å) 主引用文献 Comparison of X-ray crystal structures of a tetradecamer sequence d(CCCGGGTACCCGGG)2 at 1.7 angstrom resolution. Nucleosides Nucleotides Nucleic Acids, 36, 2017
5IYG	Comparison of X-ray crystal structures of a tetradecamer sequence d(CCCGGGTACCCGGG)2 at 1.7 resolution 分子名称: DNA (5'-D(*CP*CP*CP*GP*GP*GP*TP*AP*CP*CP*CP*GP*GP*G)-3') 著者 Karthik, S, Thirugnanasambandam, A, Mandal, P.K, Gautham, N. 登録日 2016-03-24 公開日 2017-03-29 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.701 Å) 主引用文献 Comparison of X-ray crystal structures of a tetradecamer sequence d(CCCGGGTACCCGGG)2 at 1.7 angstrom resolution. Nucleosides Nucleotides Nucleic Acids, 36, 2017
5IYJ	Comparison of X-ray crystal structures of a tetradecamer sequence d(CCCGGGTACCCGGG)2 at 1.7 resolution 分子名称: DNA (5'-D(*CP*CP*CP*GP*GP*GP*TP*AP*CP*CP*CP*GP*GP*G)-3') 著者 Karthik, S, Thirugnanasambandam, A, Mandal, P.K, Gautham, N. 登録日 2016-03-24 公開日 2017-03-29 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.701 Å) 主引用文献 Comparison of X-ray crystal structures of a tetradecamer sequence d(CCCGGGTACCCGGG)2 at 1.7 angstrom resolution. Nucleosides Nucleotides Nucleic Acids, 36, 2017
4PHW	Crystal Structure of PDE10A with 1H-benzimidazol-2-yl(4-((3-(tetrahydro-2H-pyran-4-yl)-2-pyridinyl)oxy)phenyl)methanone 分子名称: 1H-benzimidazol-2-yl(4-{[3-(tetrahydro-2H-pyran-4-yl)pyridin-2-yl]oxy}phenyl)methanone, SULFATE ION, ZINC ION, ... 著者 Chmait, S. 登録日 2014-05-07 公開日 2014-08-06 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Discovery of Clinical Candidate 1-(4-(3-(4-(1H-Benzo[d]imidazole-2-carbonyl)phenoxy)pyrazin-2-yl)piperidin-1-yl)ethanone (AMG 579), A Potent, Selective, and Efficacious Inhibitor of Phosphodiesterase 10A (PDE10A). J.Med.Chem., 57, 2014
4N00	Discovery of 7-THP chromans: BACE1 inhibitors that reduce A-beta in the CNS 分子名称: (4R,4a'S,10a'S)-2-amino-8'-(2-fluoropyridin-3-yl)-1-methyl-3',4',4a',10a'-tetrahydro-1'H-spiro[imidazole-4,10'-pyrano[4,3-b]chromen]-5(1H)-one, Beta-secretase 1, NICKEL (II) ION 著者 Vigers, G.P.A, Smith, D. 登録日 2013-09-30 公開日 2014-05-14 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Discovery of 7-tetrahydropyran-2-yl chromans: beta-site amyloid precursor protein cleaving enzyme 1 (BACE1) inhibitors that reduce amyloid beta-protein (A beta ) in the central nervous system. J.Med.Chem., 57, 2014
4ISH	Structure of FACTOR VIIA in complex with the inhibitor BMS-593214 also known as 2'-[(6R,6AR,11BR)-2-CARBAMIMIDOYL-6,6A,7,11B-TETRAHYDRO-5H-INDENO[2,1-C]QUINOLIN-6-YL]-5'-HYDROXY-4'-METHOXYBIPHENYL-4-CARBOXYLIC ACID 分子名称: 2'-[(6R,6aR,11bR)-2-carbamimidoyl-6,6a,7,11b-tetrahydro-5H-indeno[2,1-c]quinolin-6-yl]-5'-hydroxy-4'-methoxybiphenyl-4-carboxylic acid, CALCIUM ION, Factor VII heavy chain, ... 著者 Wei, A. 登録日 2013-01-16 公開日 2013-03-20 実験手法 X-RAY DIFFRACTION (1.82 Å) 主引用文献 Discovery and gram-scale synthesis of BMS-593214, a potent, selective FVIIa inhibitor. Bioorg.Med.Chem.Lett., 23, 2013
4N9A	E. coli sliding clamp in complex with (R)-6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxylic acid 分子名称: (1R)-6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxylic acid, CALCIUM ION, CHLORIDE ION, ... 著者 Yin, Z, Oakley, A.J. 登録日 2013-10-19 公開日 2013-11-06 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Discovery of lead compounds targeting the bacterial sliding clamp using a fragment-based approach. J.Med.Chem., 57, 2014
4ITF	Crystal structure of the human vitamin D receptor ligand binding domain complexed with 1alpha,25-Dihydroxy-2alpha-[2-(1H-tetrazole-1-yl)ethyl]vitamin D3 分子名称: (1R,2S,3S,5Z)-5-[(2E)-2-[(1R,3aS,7aR)-7a-methyl-1-[(2R)-6-methyl-6-oxidanyl-heptan-2-yl]-2,3,3a,5,6,7-hexahydro-1H-inden-4-ylidene]ethylidene]-4-methylidene-2-[2-(1,2,3,4-tetrazol-1-yl)ethyl]cyclohexane-1,3-diol, Vitamin D3 receptor 著者 Kakuda, S, Takimoto-Kamimura, M. 登録日 2013-01-18 公開日 2014-01-22 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.84 Å) 主引用文献 Synthesis of 2 alpha-heteroarylalkyl active vitamin d3 with therapeutic effect on enhancing bone mineral density in vivo ACS MED.CHEM.LETT., 4, 2013
4ITN	Crystal structure of "compact P-loop" LpxK from Aquifex aeolicus in complex with chloride at 2.2 angstrom resolution 分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, CHLORIDE ION, GLYCEROL, ... 著者 Emptage, R.P, Pemble IV, C.W, York, J.D, Raetz, C.R.H, Zhou, P. 登録日 2013-01-18 公開日 2013-04-03 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.1912 Å) 主引用文献 Mechanistic Characterization of the Tetraacyldisaccharide-1-phosphate 4'-Kinase LpxK Involved in Lipid A Biosynthesis. Biochemistry, 52, 2013
4ITM	Crystal structure of "apo" form LpxK from Aquifex aeolicus in complex with ATP at 2.2 angstrom resolution 分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ADENOSINE-5'-TRIPHOSPHATE, ... 著者 Emptage, R.P, Pemble IV, C.W, York, J.D, Raetz, C.R.H, Zhou, P. 登録日 2013-01-18 公開日 2013-04-03 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.1994 Å) 主引用文献 Mechanistic Characterization of the Tetraacyldisaccharide-1-phosphate 4'-Kinase LpxK Involved in Lipid A Biosynthesis. Biochemistry, 52, 2013
4N99	E. coli sliding clamp in complex with 6-chloro-2,3,4,9-tetrahydro-1H-carbazole-7-carboxylic acid 分子名称: 6-chloro-2,3,4,9-tetrahydro-1H-carbazole-7-carboxylic acid, CALCIUM ION, DI(HYDROXYETHYL)ETHER, ... 著者 Yin, Z, Oakley, A.J. 登録日 2013-10-19 公開日 2013-11-06 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Discovery of lead compounds targeting the bacterial sliding clamp using a fragment-based approach. J.Med.Chem., 57, 2014
2ZB9	Crystal structure of TetR family transcription regulator SCO0332 分子名称: Putative transcriptional regulator 著者 Okada, U, Kondo, K, Watanabe, N, Yao, M, Tanaka, I. 登録日 2007-10-16 公開日 2008-01-29 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (2.25 Å) 主引用文献 Structural and functional analysis of the TetR-family transcriptional regulator SCO0332 from Streptomyces coelicolor ACTA CRYSTALLOGR.,SECT.D, 64, 2008
3TK8	Structure of a 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase from Burkholderia pseudomallei 分子名称: 1,2-ETHANEDIOL, 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase, SULFATE ION, ... 著者 Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2011-08-25 公開日 2011-10-12 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Structure of a 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase from Burkholderia pseudomallei TO BE PUBLISHED
2ZK3	Human peroxisome proliferator-activated receptor gamma ligand binding domain complexed with 8-oxo-eicosatetraenoic acid 分子名称: (5E,11E,14E)-8-oxoicosa-5,9,11,14-tetraenoic acid, Peroxisome proliferator-activated receptor gamma 著者 Waku, T, Shiraki, T, Oyama, T, Fujimoto, Y, Morikawa, K. 登録日 2008-03-12 公開日 2009-02-24 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.58 Å) 主引用文献 Structural insight into PPARgamma activation through covalent modification with endogenous fatty acids J.Mol.Biol., 385, 2009
4JNY	Crystal structure of PutA86-630 mutant D370A complexed with L-Tetrahydro-2-furoic acid 分子名称: Bifunctional protein PutA, FLAVIN-ADENINE DINUCLEOTIDE, PENTAETHYLENE GLYCOL, ... 著者 Tanner, J.J. 登録日 2013-03-16 公開日 2013-08-28 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Involvement of the beta 3-alpha 3 Loop of the Proline Dehydrogenase Domain in Allosteric Regulation of Membrane Association of Proline Utilization A. Biochemistry, 52, 2013
5X1L	Vanillate/3-O-methylgallate O-demethylase, LigM, tetrahydrofolate complex form 分子名称: (6S)-5,6,7,8-TETRAHYDROFOLATE, 1,2-ETHANEDIOL, Vanillate/3-O-methylgallate O-demethylase 著者 Harada, A, Senda, T. 登録日 2017-01-26 公開日 2017-05-17 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 The crystal structure of a new O-demethylase from Sphingobium sp. strain SYK-6 FEBS J., 284, 2017
4J5J	Crystal Structure of Multidrug Resistant HIV-1 Protease Clinical Isolate PR20 in Complex with Amprenavir 分子名称: CHLORIDE ION, Protease, {3-[(4-AMINO-BENZENESULFONYL)-ISOBUTYL-AMINO]-1-BENZYL-2-HYDROXY-PROPYL}-CARBAMIC ACID TETRAHYDRO-FURAN-3-YL ESTER 著者 Shen, C.H, Weber, I.T. 登録日 2013-02-08 公開日 2013-05-15 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Extreme Multidrug Resistant HIV-1 Protease with 20 Mutations Is Resistant to Novel Protease Inhibitors with P1'-Pyrrolidinone or P2-Tris-tetrahydrofuran. J.Med.Chem., 56, 2013

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