4N9A
E. coli sliding clamp in complex with (R)-6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxylic acid
Summary for 4N9A
Entry DOI | 10.2210/pdb4n9a/pdb |
Related | 4N94 4N95 4N96 4N97 4N98 4N99 |
Descriptor | DNA polymerase III subunit beta, CALCIUM ION, TETRAETHYLENE GLYCOL, ... (7 entities in total) |
Functional Keywords | poliii beta, sliding clamp, dnan, transferase-transferase inhibitor complex, transferase/transferase inhibitor |
Biological source | Escherichia coli |
Cellular location | Cytoplasm: P0A988 |
Total number of polymer chains | 2 |
Total formula weight | 82188.47 |
Authors | Yin, Z.,Oakley, A.J. (deposition date: 2013-10-19, release date: 2013-11-06, Last modification date: 2023-09-20) |
Primary citation | Yin, Z.,Whittell, L.R.,Wang, Y.,Jergic, S.,Liu, M.,Harry, E.J.,Dixon, N.E.,Beck, J.L.,Kelso, M.J.,Oakley, A.J. Discovery of lead compounds targeting the bacterial sliding clamp using a fragment-based approach. J.Med.Chem., 57:2799-2806, 2014 Cited by PubMed: 24592885DOI: 10.1021/jm500122r PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.9 Å) |
Structure validation
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