4N9A

E. coli sliding clamp in complex with (R)-6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxylic acid

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003677	molecular_function	DNA binding
A	0003887	molecular_function	DNA-directed DNA polymerase activity
A	0005515	molecular_function	protein binding
A	0005737	cellular_component	cytoplasm
A	0005829	cellular_component	cytosol
A	0006260	biological_process	DNA replication
A	0006261	biological_process	DNA-templated DNA replication
A	0006271	biological_process	DNA strand elongation involved in DNA replication
A	0006974	biological_process	DNA damage response
A	0008408	molecular_function	3'-5' exonuclease activity
A	0009360	cellular_component	DNA polymerase III complex
A	0030174	biological_process	regulation of DNA-templated DNA replication initiation
A	0030894	cellular_component	replisome
A	0032297	biological_process	negative regulation of DNA-templated DNA replication initiation
A	0042276	biological_process	error-prone translesion synthesis
A	0042802	molecular_function	identical protein binding
A	0042803	molecular_function	protein homodimerization activity
A	0044787	biological_process	bacterial-type DNA replication
A	1990078	cellular_component	replication inhibiting complex
A	1990085	cellular_component	Hda-beta clamp complex
B	0003677	molecular_function	DNA binding
B	0003887	molecular_function	DNA-directed DNA polymerase activity
B	0005515	molecular_function	protein binding
B	0005737	cellular_component	cytoplasm
B	0005829	cellular_component	cytosol
B	0006260	biological_process	DNA replication
B	0006261	biological_process	DNA-templated DNA replication
B	0006271	biological_process	DNA strand elongation involved in DNA replication
B	0006974	biological_process	DNA damage response
B	0008408	molecular_function	3'-5' exonuclease activity
B	0009360	cellular_component	DNA polymerase III complex
B	0030174	biological_process	regulation of DNA-templated DNA replication initiation
B	0030894	cellular_component	replisome
B	0032297	biological_process	negative regulation of DNA-templated DNA replication initiation
B	0042276	biological_process	error-prone translesion synthesis
B	0042802	molecular_function	identical protein binding
B	0042803	molecular_function	protein homodimerization activity
B	0044787	biological_process	bacterial-type DNA replication
B	1990078	cellular_component	replication inhibiting complex
B	1990085	cellular_component	Hda-beta clamp complex

Functional Information from PDB Data

site_id	AC1
Number of Residues	1
Details	BINDING SITE FOR RESIDUE CA A 401

Chain	Residue
B	HOH641

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site_id	AC2
Number of Residues	5
Details	BINDING SITE FOR RESIDUE PG4 A 402

Chain	Residue
A	ASP121
A	TRP122
A	ARG224
B	SER43
B	HOH567

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site_id	AC3
Number of Residues	4
Details	BINDING SITE FOR RESIDUE CA A 403

Chain	Residue
A	HOH600
A	GLY280
A	ALA294
A	ASN295

---

site_id	AC4
Number of Residues	6
Details	BINDING SITE FOR RESIDUE 2J2 A 404

Chain	Residue
A	THR172
A	GLY174
A	ARG176
A	PRO242
A	VAL247
A	MET362

---

site_id	AC5
Number of Residues	8
Details	BINDING SITE FOR RESIDUE PEG A 405

Chain	Residue
A	SER345
A	HOH529
A	HOH673
B	GLU163
B	GLU166
B	ARG168
B	HOH638
B	HOH674

---

site_id	AC6
Number of Residues	4
Details	BINDING SITE FOR RESIDUE PEG A 406

Chain	Residue
A	ALA114
A	PHE116
A	PRO117
A	ASN118

---

site_id	AC7
Number of Residues	2
Details	BINDING SITE FOR RESIDUE CL A 407

Chain	Residue
A	SER181
A	HOH621

---

site_id	AC8
Number of Residues	7
Details	BINDING SITE FOR RESIDUE CL A 408

Chain	Residue
A	THR4
A	VAL5
A	LEU59
A	VAL60
A	GLN61
A	HOH518
A	HOH519

---

site_id	AC9
Number of Residues	1
Details	BINDING SITE FOR RESIDUE CA B 401

Chain	Residue
B	ASP211

---

site_id	BC1
Number of Residues	2
Details	BINDING SITE FOR RESIDUE CA B 402

Chain	Residue
B	GLY46
B	GLU202

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site_id	BC2
Number of Residues	5
Details	BINDING SITE FOR RESIDUE CA B 403

Chain	Residue
A	THR341
A	HOH578
A	HOH719
B	HOH533
B	HOH580

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	6
Details	BINDING: BINDING => ECO:0000305|PubMed:18191219

Chain	Residue	Details
A	ARG24
A	GLN149
A	TYR153
B	ARG24
B	GLN149
B	TYR153

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site_id	SWS_FT_FI2
Number of Residues	2
Details	BINDING: BINDING => ECO:0000269|PubMed:18191219

Chain	Residue	Details
A	ARG73
B	ARG73

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