5CP6
Nucleosome Core Particle with Adducts from the Anticancer Compound, [(eta6-5,8,9,10-tetrahydroanthracene)Ru(ethylenediamine)Cl][PF6]
Summary for 5CP6
Entry DOI | 10.2210/pdb5cp6/pdb |
Descriptor | DNA (145-MER), Histone H3.2, Histone H4, ... (10 entities in total) |
Functional Keywords | nucleosome core particle, antitumour compound, structural protein-dna complex, structural protein/dna |
Biological source | Xenopus laevis (African clawed frog) More |
Cellular location | Nucleus: P84233 P62799 P02281 |
Total number of polymer chains | 10 |
Total formula weight | 199584.29 |
Authors | Ma, Z.,Adhireksan, Z.,Murray, B.S.,Dyson, P.J.,Davey, C.A. (deposition date: 2015-07-21, release date: 2016-06-01, Last modification date: 2023-11-08) |
Primary citation | Ma, Z.,Palermo, G.,Adhireksan, Z.,Murray, B.S.,von Erlach, T.,Dyson, P.J.,Rothlisberger, U.,Davey, C.A. An Organometallic Compound which Exhibits a DNA Topology-Dependent One-Stranded Intercalation Mode. Angew.Chem.Int.Ed.Engl., 55:7441-7444, 2016 Cited by PubMed: 27184539DOI: 10.1002/anie.201602145 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.6 Å) |
Structure validation
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