6QRK
 
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6QQ7
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6QQG
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2A3G
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1ZEI
 | | CROSS-LINKED B28 ASP INSULIN | | 分子名称: | CHLORIDE ION, INSULIN, M-CRESOL, ... | | 著者 | Whittingham, J.L, Edwards, E.J, Antson, A.A, Clarkson, J.M, Dodson, G.G. | | 登録日 | 1998-07-14 | | 公開日 | 1999-02-16 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Interactions of phenol and m-cresol in the insulin hexamer, and their effect on the association properties of B28 pro --> Asp insulin analogues.
Biochemistry, 37, 1998
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2RN5
 | | Humal Insulin Mutant B31Lys-B32Arg | | 分子名称: | Insulin | | 著者 | Bocian, W, Kozerski, L. | | 登録日 | 2007-12-06 | | 公開日 | 2008-10-28 | | 最終更新日 | 2022-03-16 | | 実験手法 | SOLUTION NMR | | 主引用文献 | NMR structure of biosynthetic engineered human insulin monomer B31(Lys)-B32(Arg) in water/acetonitrile solution. Comparison with the solution structure of native human insulin monomer
Biopolymers, 89, 2008
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2VJZ
 | | Crystal structure form ultalente insulin microcrystals | | 分子名称: | CHLORIDE ION, INSULIN A CHAIN, INSULIN B CHAIN, ... | | 著者 | Wagner, A, Diez, J, Schulze-Briese, C, Schluckebier, G. | | 登録日 | 2007-12-14 | | 公開日 | 2008-09-16 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Crystal Structure of Ultralente-A Microcrystalline Insulin Suspension.
Proteins, 74, 2009
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2VK0
 | | Crystal structure form ultalente insulin microcrystals | | 分子名称: | 4-HYDROXY-BENZOIC ACID METHYL ESTER, INSULIN A CHAIN, INSULIN B CHAIN, ... | | 著者 | Wagner, A, Diez, J, Schulze-Briese, C, Schluckebier, G. | | 登録日 | 2007-12-14 | | 公開日 | 2008-09-16 | | 最終更新日 | 2024-05-01 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Crystal Structure of Ultralente--A Microcrystalline Insulin Suspension.
Proteins, 74, 2009
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2WS0
 | | Semi-synthetic analogue of human insulin NMeAlaB26-insulin at pH 7.5 | | 分子名称: | INSULIN A CHAIN, INSULIN B CHAIN | | 著者 | Brzozowski, A.M, Jiracek, J, Zakova, L, Antolikova, E, Watson, C.J, Turkenburg, J.P, Dodson, G.G. | | 登録日 | 2009-09-03 | | 公開日 | 2010-02-09 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Implications for the Active Form of Human Insulin Based on the Structural Convergence of Highly Active Hormone Analogues.
Proc.Natl.Acad.Sci.USA, 107, 2010
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2W44
 | | Structure DeltaA1-A4 insulin | | 分子名称: | CHLORIDE ION, INSULIN, RESORCINOL, ... | | 著者 | Thorsoee, K.S, Schlein, M, Brandt, J, Schluckebier, G, Naver, H. | | 登録日 | 2008-11-21 | | 公開日 | 2009-12-22 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Kinetic Evidence for the Sequential Association of Insulin Binding Sites 1 and 2 to the Insulin Receptor and the Influence of Receptor Isoform.
Biochemistry, 49, 2010
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2WS6
 | | Semi-synthetic analogue of human insulin NMeTyrB26-insulin in hexamer form | | 分子名称: | CHLORIDE ION, GLYCEROL, INSULIN A CHAIN, ... | | 著者 | Brzozowski, A.M, Jiracek, J, Zakova, L, Antolikova, E, Watson, C.J, Turkenburg, J.P, Dodson, G.G. | | 登録日 | 2009-09-03 | | 公開日 | 2010-02-09 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | Implications for the Active Form of Human Insulin Based on the Structural Convergence of Highly Active Hormone Analogues.
Proc.Natl.Acad.Sci.USA, 107, 2010
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2WRX
 | | Semi-synthetic analogue of human insulin NMeAlaB26-insulin at pH 3.0 | | 分子名称: | INSULIN A CHAIN, INSULIN B CHAIN, SODIUM ION | | 著者 | Brzozowski, A.M, Jiracek, J, Zakova, L, Antolikova, E, Watson, C.J, Turkenburg, J.P, Dodson, G.G. | | 登録日 | 2009-09-02 | | 公開日 | 2010-02-09 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | Implications for the Active Form of Human Insulin Based on the Structural Convergence of Highly Active Hormone Analogues.
Proc.Natl.Acad.Sci.USA, 107, 2010
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2TCI
 | | X-RAY CRYSTALLOGRAPHIC STUDIES ON HEXAMERIC INSULINS IN THE PRESENCE OF HELIX-STABILIZING AGENTS, THIOCYANATE, METHYLPARABEN AND PHENOL | | 分子名称: | THIOCYANATE INSULIN, THIOCYANATE ION, ZINC ION | | 著者 | Whittingham, J.L, Dodson, E.J, Moody, P.C.E, Dodson, G.G. | | 登録日 | 1995-09-13 | | 公開日 | 1996-01-29 | | 最終更新日 | 2024-06-05 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | X-ray crystallographic studies on hexameric insulins in the presence of helix-stabilizing agents, thiocyanate, methylparaben, and phenol.
Biochemistry, 34, 1995
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2WS1
 | | Semi-synthetic analogue of human insulin NMeTyrB26-insulin in monomer form | | 分子名称: | ACETATE ION, INSULIN A CHAIN, INSULIN B CHAIN | | 著者 | Brzozowski, A.M, Jiracek, J, Zakova, L, Antolikova, E, Watson, C.J, Turkenburg, J.P, Dodson, G.G. | | 登録日 | 2009-09-03 | | 公開日 | 2010-02-09 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Implications for the Active Form of Human Insulin Based on the Structural Convergence of Highly Active Hormone Analogues.
Proc.Natl.Acad.Sci.USA, 107, 2010
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4GBN
 | | Crystal structure of aspart insulin at pH 6.5 | | 分子名称: | CHLORIDE ION, Insulin A chain, Insulin B chain, ... | | 著者 | Lima, L.M.T.R, Favero-Retto, M.P, Palmieri, L.C. | | 登録日 | 2012-07-27 | | 公開日 | 2013-06-12 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (1.872 Å) | | 主引用文献 | A T3R3 hexamer of the human insulin variant B28Asp.
Biophys.Chem., 173, 2013
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4GBC
 | | Crystal structure of aspart insulin at pH 6.5 | | 分子名称: | CHLORIDE ION, Insulin A chain, Insulin B chain, ... | | 著者 | Lima, L.M.T.R, Favero-Retto, M.P, Palmieri, L.C. | | 登録日 | 2012-07-27 | | 公開日 | 2013-06-12 | | 最終更新日 | 2018-08-22 | | 実験手法 | X-RAY DIFFRACTION (1.778 Å) | | 主引用文献 | A T3R3 hexamer of the human insulin variant B28Asp.
Biophys.Chem., 173, 2013
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4GBK
 | | Crystal structure of aspart insulin at pH 8.5 | | 分子名称: | CHLORIDE ION, Insulin A chain, Insulin B chain, ... | | 著者 | Lima, L.M.T.R, Favero-Retto, M.P, Palmieri, L.C. | | 登録日 | 2012-07-27 | | 公開日 | 2013-06-12 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | A T3R3 hexamer of the human insulin variant B28Asp.
Biophys.Chem., 173, 2013
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4GBI
 | | Crystal structure of aspart insulin at pH 6.5 | | 分子名称: | CHLORIDE ION, Insulin A chain, Insulin B chain, ... | | 著者 | Lima, L.M.T.R, Favero-Retto, M.P, Palmieri, L.C. | | 登録日 | 2012-07-27 | | 公開日 | 2013-06-12 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (2.502 Å) | | 主引用文献 | A T3R3 hexamer of the human insulin variant B28Asp.
Biophys.Chem., 173, 2013
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4GBL
 | | Crystal structure of aspart insulin at pH 8.5 | | 分子名称: | CHLORIDE ION, Insulin A chain, Insulin B chain, ... | | 著者 | Lima, L.M.T.R, Favero-Retto, M.P, Palmieri, L.C. | | 登録日 | 2012-07-27 | | 公開日 | 2013-06-12 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | A T3R3 hexamer of the human insulin variant B28Asp.
Biophys.Chem., 173, 2013
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4I5Z
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4I5Y
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4IDW
 | | Polycrystalline T6 Bovine Insulin: Anisotropic Lattice Evolution and Novel Structure Refinement Strategy | | 分子名称: | Insulin A chain, Insulin B chain, ZINC ION | | 著者 | Margiolaki, I, Giannopoulou, A.E, Wright, J.P, Knight, L, Norrman, M, Schluckebier, G, Fitch, A, Von Dreele, R.B. | | 登録日 | 2012-12-13 | | 公開日 | 2013-06-05 | | 実験手法 | POWDER DIFFRACTION | | 主引用文献 | High-resolution powder X-ray data reveal the T6 hexameric form of bovine insulin
Acta Crystallogr.,Sect.D, 69, 2013
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4FKA
 | | High resolution structure of the manganese derivative of insulin | | 分子名称: | Insulin A chain, Insulin B chain, MANGANESE (II) ION, ... | | 著者 | Prugovecki, B, Pulic, I, Toth, M, Matkovic-Calogovic, D. | | 登録日 | 2012-06-13 | | 公開日 | 2013-02-13 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (1.08 Å) | | 主引用文献 | High Resolution Structure of the Manganese Derivative of Insulin
Croat.Chem.Acta, 85, 2012
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4FG3
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4INS
 | | THE STRUCTURE OF 2ZN PIG INSULIN CRYSTALS AT 1.5 ANGSTROMS RESOLUTION | | 分子名称: | INSULIN (CHAIN A), INSULIN (CHAIN B), ZINC ION | | 著者 | Dodson, G.G, Dodson, E.J, Hodgkin, D.C, Isaacs, N.W, Vijayan, M. | | 登録日 | 1989-07-10 | | 公開日 | 1990-04-15 | | 最終更新日 | 2017-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | The structure of 2Zn pig insulin crystals at 1.5 A resolution.
Philos.Trans.R.Soc.London,Ser.B, 319, 1988
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