5UDP

High resolution x-ray crystal structure of synthetic insulin lispro

Summary for 5UDP

• Entry DOI: 10.2210/pdb5udp/pdb
• Descriptor: Insulin Lispro A chain, Insulin Lispro B chain, PHENOL, ... (7 entities in total)
• Functional Keywords: insulin lispro, chemical protein synthesis, fmoc chemistry, hormone
• Biological source: Homo sapiens (Human); More
• Cellular location: Secreted: P01308 P01308
• Total number of polymer chains: 12
• Total formula weight: 35695.29

Authors

Mandal, K.,Dhayalan, B.,Kent, S.B.H. (deposition date: 2016-12-28, release date: 2017-01-11, Last modification date: 2023-10-04)

• Primary citation: Dhayalan, B.,Mandal, K.,Rege, N.,Weiss, M.A.,Eitel, S.H.,Meier, T.,Schoenleber, R.O.,Kent, S.B.; Scope and Limitations of Fmoc Chemistry SPPS-Based Approaches to the Total Synthesis of Insulin Lispro via Ester Insulin.; Chemistry, 23:1709-1716, 2017; PubMed: 27905149; DOI: 10.1002/chem.201605578

Experimental method

X-RAY DIFFRACTION (1.348 Å)