5UDP
High resolution x-ray crystal structure of synthetic insulin lispro
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C, E, G, I... (A, C, E, G, I...) | Insulin Lispro A chain | polymer | 21 | 2383.7 | 6 | UniProt (P01308) | Homo sapiens | |
| 2 | B, D, F, H, J... (B, D, F, H, J...) | Insulin Lispro B chain | polymer | 30 | 3434.0 | 6 | UniProt (P01308) Pfam (PF00049) | Homo sapiens | |
| 3 | M, P, T, U, V... (A, C, E, G, I...) | PHENOL | non-polymer | 94.1 | 6 | Chemie (IPH) | |||
| 4 | N, R (B, D) | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
| 5 | O, S (B, D) | CHLORIDE ION | non-polymer | 35.5 | 2 | Chemie (CL) | |||
| 6 | Q (C) | SODIUM ION | non-polymer | 23.0 | 1 | Chemie (NA) | |||
| 7 | AA, BA, CA, DA, EA... (D, E, F, G, H...) | water | water | 18.0 | 202 | Chemie (HOH) |
Sequence modifications
B, D, F, H, J, L: 1 - 30 (UniProt: P01308)
| PDB | External Database | Details |
|---|---|---|
| Lys 28 | Pro 52 | engineered mutation |
| Pro 29 | Lys 53 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 12 |
| Total formula weight | 34905.9 | |
| Non-Polymers* | Number of molecules | 11 |
| Total formula weight | 789.4 | |
| All* | Total formula weight | 35695.3 |
