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5BTS

Structural and biophysical characterization of a covalent insulin dimer formed during storage of neutral formulation of human insulin

Summary for 5BTS
Entry DOI10.2210/pdb5bts/pdb
DescriptorInsulin A chain, Insulin B chain (3 entities in total)
Functional Keywordsinsulin, hormone, hmwp
Biological sourceHomo sapiens (Human)
More
Total number of polymer chains2
Total formula weight5817.65
Authors
Norrman, M.,Hjorth, C.F. (deposition date: 2015-06-03, release date: 2016-03-09, Last modification date: 2019-02-20)
Primary citationHjorth, C.F.,Norrman, M.,Wahlund, P.O.,Benie, A.J.,Petersen, B.O.,Jessen, C.M.,Pedersen, T.A.,Vestergaard, K.,Steensgaard, D.B.,Pedersen, J.S.,Naver, H.,Hubalek, F.,Poulsen, C.,Otzen, D.
Structure, Aggregation, and Activity of a Covalent Insulin Dimer Formed During Storage of Neutral Formulation of Human Insulin.
J.Pharm.Sci., 105:1376-1386, 2016
Cited by
PubMed: 26921119
DOI: 10.1016/j.xphs.2016.01.003
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.77 Å)
Structure validation

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