5BOQ
Human insulin with intra-chain chemical crosslink between modified B24 and B29
Summary for 5BOQ
Entry DOI | 10.2210/pdb5boq/pdb |
Related | 5BPO 5BQQ |
Descriptor | Insulin, SULFATE ION, ... (4 entities in total) |
Functional Keywords | hormone, chemical crosslink, b24-b29, specificity |
Biological source | Homo sapiens (Human) More |
Cellular location | Secreted: P01308 P01308 |
Total number of polymer chains | 8 |
Total formula weight | 23458.52 |
Authors | Brzozowski, A.M.,Turkenburg, J.P.,Jiracek, J.,Zakova, L. (deposition date: 2015-05-27, release date: 2016-02-03, Last modification date: 2024-01-10) |
Primary citation | Vikova, J.,Collinsova, M.,Kletvikova, E.,Budesinsky, M.,Kaplan, V.,Zakova, L.,Veverka, V.,Hexnerova, R.,Avino, R.J.,Strakova, J.,Selicharova, I.,Vanek, V.,Wright, D.W.,Watson, C.J.,Turkenburg, J.P.,Brzozowski, A.M.,Jiracek, J. Rational steering of insulin binding specificity by intra-chain chemical crosslinking. Sci Rep, 6:19431-19431, 2016 Cited by PubMed: 26792393DOI: 10.1038/srep19431 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.7 Å) |
Structure validation
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