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1XI5
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Clathrin D6 coat with auxilin J-domain
分子名称: Auxilin J-domain, Clathrin heavy chain
著者Fotin, A, Cheng, Y, Grigorieff, N, Walz, T, Harrison, S.C, Kirchhausen, T.
登録日2004-09-21
公開日2004-11-02
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (12 Å)
主引用文献Structure of an auxilin-bound clathrin coat and its implications for the mechanism of uncoating
Nature, 432, 2004
4Q37
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BU of 4q37 by Molmil
Crystal structure of the hypothetical protein TM0182 Thermotoga maritima, N-terminal domain.
分子名称: PLATINUM (II) ION, Radical SAM protein
著者Hocker, B, Farias-Rico, J.A.
登録日2014-04-11
公開日2014-07-16
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (3.19 Å)
主引用文献Evolutionary relationship of two ancient protein superfolds.
Nat.Chem.Biol., 10, 2014
3J9Z
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Activation of GTP Hydrolysis in mRNA-tRNA Translocation by Elongation Factor G
分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
著者Li, W, Liu, Z, Koripella, R.K, Langlois, R, Sanyal, S, Frank, J.
登録日2015-03-27
公開日2015-07-01
最終更新日2024-02-21
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Activation of GTP hydrolysis in mRNA-tRNA translocation by elongation factor G.
Sci Adv, 1, 2015
1XM8
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BU of 1xm8 by Molmil
X-RAY STRUCTURE OF GLYOXALASE II FROM ARABIDOPSIS THALIANA GENE AT2G31350
分子名称: ACETIC ACID, DI(HYDROXYETHYL)ETHER, FE (III) ION, ...
著者Wesenberg, G.E, Smith, D.W, Phillips Jr, G.N, Bitto, E, Bingman, C.A, Allard, S.T.M, Center for Eukaryotic Structural Genomics (CESG)
登録日2004-10-01
公開日2004-10-12
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.74 Å)
主引用文献Structural studies on a mitochondrial glyoxalase II.
J.Biol.Chem., 280, 2005
4QLQ
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BU of 4qlq by Molmil
yCP in complex with tripeptidic epoxyketone inhibitor 8
分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, MAGNESIUM ION, N-(morpholin-4-ylacetyl)-L-alanyl-N-[(2S,4R)-1-cyclohexyl-5-hydroxy-4-methyl-3-oxopentan-2-yl]-O-methyl-L-tyrosinamide, ...
著者De Bruin, G, Huber, E, Xin, B, Van Rooden, E, Al-Ayed, K, Kim, K, Kisselev, A, Driessen, C, Van der Marel, G, Groll, M, Overkleeft, H.
登録日2014-06-13
公開日2014-07-23
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structure-based design of beta 1i or beta 5i specific inhibitors of human immunoproteasomes
J.Med.Chem., 57, 2014
3OOH
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BU of 3ooh by Molmil
Crystal structure of E. Coli purine nucleoside phosphorylase with PO4
分子名称: PHOSPHATE ION, Purine nucleoside phosphorylase deoD-type
著者Mikleusevic, G, Stefanic, Z, Narzyk, M, Wielgus-Kutrowska, B, Bzowska, A, Luic, M.
登録日2010-08-31
公開日2011-07-13
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Validation of the catalytic mechanism of Escherichia coli purine nucleoside phosphorylase by structural and kinetic studies.
Biochimie, 93, 2011
3JBT
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BU of 3jbt by Molmil
Atomic structure of the Apaf-1 apoptosome
分子名称: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, Apoptotic protease-activating factor 1, Cytochrome c, ...
著者Zhou, M, Li, Y, Hu, Q, Bai, X, Huang, W, Yan, C, Scheres, S.H.W, Shi, Y.
登録日2015-10-15
公開日2015-11-18
最終更新日2019-12-18
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献Atomic structure of the apoptosome: mechanism of cytochrome c- and dATP-mediated activation of Apaf-1
Genes Dev., 29, 2015
3JCD
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BU of 3jcd by Molmil
Structure of Escherichia coli EF4 in posttranslocational ribosomes (Post EF4)
分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
著者Zhang, D, Yan, K, Liu, G, Song, G, Luo, J, Shi, Y, Cheng, E, Wu, S, Jiang, T, Low, J, Gao, N, Qin, Y.
登録日2015-12-01
公開日2016-01-13
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献EF4 disengages the peptidyl-tRNA CCA end and facilitates back-translocation on the 70S ribosome
Nat. Struct. Mol. Biol., 23, 2016
3J6Y
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BU of 3j6y by Molmil
S. cerevisiae 80S ribosome bound with Taura syndrome virus (TSV) IRES, 2 degree rotation (Class I)
分子名称: 18S ribosomal RNA, 25S ribosomal RNA, 40S ribosomal protein S0, ...
著者Koh, C.S, Brilot, A.F, Grigorieff, N, Korostelev, A.A.
登録日2014-04-16
公開日2014-06-11
最終更新日2024-02-21
実験手法ELECTRON MICROSCOPY (6.1 Å)
主引用文献Taura syndrome virus IRES initiates translation by binding its tRNA-mRNA-like structural element in the ribosomal decoding center.
Proc.Natl.Acad.Sci.USA, 111, 2014
4FJV
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BU of 4fjv by Molmil
Crystal Structure of Human Otubain2 and Ubiquitin Complex
分子名称: ETHANAMINE, GLYCEROL, Polyubiquitin-C, ...
著者Altun, M, Walter, T.S, Kramer, H.B, Iphofer, A, David, Y, Komsany, A, Ternette, N, Nicholson, B, Navon, A, Stuart, D.I, Ren, J, Kessler, B.M.
登録日2012-06-12
公開日2013-06-12
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.047 Å)
主引用文献The human otubain2-ubiquitin structure provides insights into the cleavage specificity of poly-ubiquitin-linkages.
Plos One, 10, 2015
1XRF
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BU of 1xrf by Molmil
The Crystal Structure of a Novel, Latent Dihydroorotase from Aquifex aeolicus at 1.7 A resolution
分子名称: Dihydroorotase, SULFATE ION, ZINC ION
著者Martin, P.D, Purcarea, C, Zhang, P, Vaishnav, A, Sadecki, S, Guy-Evans, H.I, Evans, D.R, Edwards, B.F.
登録日2004-10-14
公開日2005-07-05
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献The crystal structure of a novel, latent dihydroorotase from Aquifex aeolicus at 1.7A resolution
J.Mol.Biol., 348, 2005
7A08
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BU of 7a08 by Molmil
CryoEM Structure of cGAS Nucleosome complex
分子名称: Cyclic GMP-AMP synthase, Histone H2A type 1-C, Histone H2B type 1-C/E/F/G/I, ...
著者Michalski, S, de Oliveira Mann, C.C, Witte, G, Bartho, J, Lammens, K, Hopfner, K.P.
登録日2020-08-07
公開日2020-09-23
最終更新日2021-02-10
実験手法ELECTRON MICROSCOPY (3.11 Å)
主引用文献Structural basis for sequestration and autoinhibition of cGAS by chromatin.
Nature, 587, 2020
3KA2
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BU of 3ka2 by Molmil
Crystal structure of chemically synthesized 203 amino acid 'covalent dimer' [L-Ala;Gly51']HIV-1 protease molecule complexed with MVT-101 reduced isostere inhibitor at 1.4 A resolution
分子名称: N-{(2S)-2-[(N-acetyl-L-threonyl-L-isoleucyl)amino]hexyl}-L-norleucyl-L-glutaminyl-N~5~-[amino(iminio)methyl]-L-ornithinamide, [L-Ala51;Gly51']HIV-1 protease
著者Torbeev, V.Y, Kent, S.B.H.
登録日2009-10-18
公開日2011-04-27
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Protein conformational dynamics in the mechanism of HIV-1 protease catalysis.
Proc.Natl.Acad.Sci.USA, 108, 2011
1XJ6
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BU of 1xj6 by Molmil
Structure of bjFixLH in the unliganded ferrous form
分子名称: CHLORIDE ION, PROTOPORPHYRIN IX CONTAINING FE, SODIUM ION, ...
著者Key, J, Moffat, K.
登録日2004-09-22
公開日2005-03-29
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Crystal Structures of Deoxy and CO-Bound bjFixLH Reveal Details of Ligand Recognition and Signaling
Biochemistry, 44, 2005
3JBV
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BU of 3jbv by Molmil
Mechanisms of Ribosome Stalling by SecM at Multiple Elongation Steps
分子名称: 30S ribosomal protein S10, 30S ribosomal protein S11, 30S ribosomal protein S12, ...
著者Zhang, J, Pan, X.J, Yan, K.G, Sun, S, Gao, N, Sui, S.F.
登録日2015-10-16
公開日2016-01-27
最終更新日2023-12-27
実験手法ELECTRON MICROSCOPY (3.32 Å)
主引用文献Mechanisms of ribosome stalling by SecM at multiple elongation steps
Elife, 4, 2015
1X8P
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BU of 1x8p by Molmil
0.85 A Crystal Structure Of Nitrophorin 4 From Rhodnius Prolixus Complexed With Ammonia at pH 7.4
分子名称: AMMONIA, Nitrophorin 4, PROTOPORPHYRIN IX CONTAINING FE
著者Kondrashov, D.A, Roberts, S.A, Weichsel, A, Montfort, W.R.
登録日2004-08-18
公開日2004-10-05
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (0.85 Å)
主引用文献Protein functional cycle viewed at atomic resolution: conformational change and mobility in nitrophorin 4 as a function of pH and NO binding
Biochemistry, 43, 2004
3OOF
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BU of 3oof by Molmil
Crystal structure of human FXR in complex with 4-({(2S)-2-[2-(4-chlorophenyl)-5,6-difluoro-1H-benzimidazol-1-yl]-2-cyclohexylacetyl}amino)benzoic acid
分子名称: 4-({(2S)-2-[2-(4-chlorophenyl)-5,6-difluoro-1H-benzimidazol-1-yl]-2-cyclohexylacetyl}amino)benzoic acid, Bile acid receptor, peptide of Nuclear receptor coactivator 1
著者Rudolph, M.G.
登録日2010-08-31
公開日2011-01-19
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.29 Å)
主引用文献Optimization of a novel class of benzimidazole-based farnesoid X receptor (FXR) agonists to improve physicochemical and ADME properties
Bioorg.Med.Chem.Lett., 21, 2011
6ZNL
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BU of 6znl by Molmil
Cryo-EM structure of the dynactin complex
分子名称: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ARP1 actin related protein 1 homolog A, ...
著者Lau, C.K, Lacey, S.E, Carter, A.P.
登録日2020-07-06
公開日2020-07-29
最終更新日2024-05-01
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献Cryo-EM reveals the complex architecture of dynactin's shoulder region and pointed end.
Embo J., 40, 2021
3JBO
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BU of 3jbo by Molmil
Cryo-electron microscopy reconstruction of the Plasmodium falciparum 80S ribosome bound to P/E-tRNA
分子名称: 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein eS1, ...
著者Sun, M, Li, W, Blomqvist, K, Das, S, Hashem, Y, Dvorin, J.D, Frank, J.
登録日2015-09-16
公開日2015-10-14
最終更新日2024-02-21
実験手法ELECTRON MICROSCOPY (5.8 Å)
主引用文献Dynamical features of the Plasmodium falciparum ribosome during translation.
Nucleic Acids Res., 43, 2015
3OX2
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BU of 3ox2 by Molmil
X-ray Structural study of quinone reductase II inhibition by compounds with micromolar to nanomolar range IC50 values
分子名称: 2-hydroxy-8,9-dimethoxy-6H-isoindolo[2,1-a]indol-6-one, FLAVIN-ADENINE DINUCLEOTIDE, Ribosyldihydronicotinamide dehydrogenase [quinone], ...
著者Pegan, S.D, Sturdy, M, Mesecar, A.D.
登録日2010-09-21
公開日2011-05-25
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.41 Å)
主引用文献X-ray structural studies of quinone reductase 2 nanomolar range inhibitors.
Protein Sci., 20, 2011
3J7A
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BU of 3j7a by Molmil
Cryo-EM structure of the Plasmodium falciparum 80S ribosome bound to the anti-protozoan drug emetine, small subunit
分子名称: 18S ribosomal RNA, 40S ribosomal protein eS1, 40S ribosomal protein eS10, ...
著者Wong, W, Bai, X.C, Brown, A, Fernandez, I.S, Hanssen, E, Condron, M, Tan, Y.H, Baum, J, Scheres, S.H.W.
登録日2014-06-03
公開日2014-07-16
最終更新日2018-07-18
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Cryo-EM structure of the Plasmodium falciparum 80S ribosome bound to the anti-protozoan drug emetine.
Elife, 3, 2014
3J81
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BU of 3j81 by Molmil
CryoEM structure of a partial yeast 48S preinitiation complex
分子名称: 18S rRNA, MAGNESIUM ION, METHIONINE, ...
著者Hussain, T, Llacer, J.L, Fernandez, I.S, Savva, C.G, Ramakrishnan, V.
登録日2014-08-29
公開日2014-11-05
最終更新日2024-02-21
実験手法ELECTRON MICROSCOPY (4 Å)
主引用文献Structural changes enable start codon recognition by the eukaryotic translation initiation complex.
Cell(Cambridge,Mass.), 159, 2014
5MD3
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BU of 5md3 by Molmil
The structure of the mature HIV-1 CA hexameric lattice with curvature parameters: tilt=11, twist=12
分子名称: Capsid protein p24
著者Mattei, S, Glass, B, Hagen, W.J.H, Kraeusslich, H.-G, Briggs, J.A.G.
登録日2016-11-10
公開日2016-12-28
最終更新日2024-05-15
実験手法ELECTRON MICROSCOPY (8.5 Å)
主引用文献The structure and flexibility of conical HIV-1 capsids determined within intact virions.
Science, 354, 2016
5MDE
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BU of 5mde by Molmil
The structure of the mature HIV-1 CA hexameric lattice with curvature parameters: tilt=23, twist=0
分子名称: Capsid protein p24 C-terminal domain, Capsid protein p24 N-terminal domain
著者Mattei, S, Glass, B, Hagen, W.J.H, Kraeusslich, H.-G, Briggs, J.A.G.
登録日2016-11-10
公開日2016-12-28
最終更新日2024-05-15
実験手法ELECTRON MICROSCOPY (8.4 Å)
主引用文献The structure and flexibility of conical HIV-1 capsids determined within intact virions.
Science, 354, 2016
1YRT
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BU of 1yrt by Molmil
Crystal Structure analysis of the adenylyl cyclaes catalytic domain of adenylyl cyclase toxin of Bordetella pertussis in presence of c-terminal calmodulin
分子名称: Bifunctional hemolysin-adenylate cyclase, CALCIUM ION, Calmodulin
著者Guo, Q, Shen, Y, Lee, Y.S, Gibbs, C.S, Mrksich, M, Tang, W.J.
登録日2005-02-04
公開日2006-01-17
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structural basis for the interaction of Bordetella pertussis adenylyl cyclase toxin with calmodulin.
Embo J., 24, 2005

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