Crystal Structure analysis of the adenylyl cyclaes catalytic domain of adenylyl cyclase toxin of Bordetella pertussis in presence of c-terminal calmodulin

Summary for 1YRT

DescriptorBifunctional hemolysin-adenylate cyclase, Calmodulin, CALCIUM ION, ... (4 entities in total)
Functional Keywordscyaa, cam, layse, toxin
Biological sourceBordetella pertussis
Cellular locationSecreted P15318
Cytoplasm, cytoskeleton, spindle P62158
Total number of polymer chains2
Total molecular weight48057.4
Guo, Q.,Shen, Y.,Lee, Y.S.,Gibbs, C.S.,Mrksich, M.,Tang, W.J. (deposition date: 2005-02-04, release date: 2006-01-17, Last modification date: 2011-07-13)
Primary citation
Guo, Q.,Shen, Y.,Lee, Y.S.,Gibbs, C.S.,Mrksich, M.,Tang, W.J.
Structural basis for the interaction of Bordetella pertussis adenylyl cyclase toxin with calmodulin.
Embo J., 24:3190-3201, 2005
PubMed: 16138079 (PDB entries with the same primary citation)
DOI: 10.1038/sj.emboj.7600800
MImport into Mendeley
Experimental method
NMR Information

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.269221.0%10.9%7.4%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation report