6W9M
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6W9L
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![BU of 6w9l by Molmil](/molmil-images/mine/6w9l) | Structure of the Ancestral Glucocorticoid Receptor 2 ligand binding domain in complex with deacetylated deflazacort and PGC1a coregulator fragment | 分子名称: | (4aR,4bS,5S,6aS,6bS,9aR,10aS,10bS)-5-hydroxy-6b-(hydroxyacetyl)-4a,6a,8-trimethyl-4a,4b,5,6,6a,6b,9a,10,10a,10b,11,12-dodecahydro-2H-naphtho[2',1':4,5]indeno[1,2-d][1,3]oxazol-2-one, GLYCEROL, Glucocorticoid Receptor, ... | 著者 | Liu, X, Ortlund, E.A. | 登録日 | 2020-03-23 | 公開日 | 2020-11-04 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (1.45 Å) | 主引用文献 | Disruption of a key ligand-H-bond network drives dissociative properties in vamorolone for Duchenne muscular dystrophy treatment. Proc.Natl.Acad.Sci.USA, 117, 2020
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3BRD
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![BU of 3brd by Molmil](/molmil-images/mine/3brd) | CSL (Lag-1) bound to DNA with Lin-12 RAM peptide, P212121 | 分子名称: | 1,2-ETHANEDIOL, DNA (5'-D(*DAP*DAP*DTP*DCP*DTP*DTP*DTP*DCP*DCP*DCP*DAP*DCP*DAP*DGP*DT)-3'), DNA (5'-D(*DTP*DTP*DAP*DCP*DTP*DGP*DTP*DGP*DGP*DGP*DAP*DAP*DAP*DGP*DA)-3'), ... | 著者 | Wilson, J.J, Kovall, R.A. | 登録日 | 2007-12-21 | 公開日 | 2008-04-01 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2.21 Å) | 主引用文献 | RAM-induced Allostery Facilitates Assembly of a Notch Pathway Active Transcription Complex. J.Biol.Chem., 283, 2008
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3BP8
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![BU of 3bp8 by Molmil](/molmil-images/mine/3bp8) | Crystal structure of Mlc/EIIB complex | 分子名称: | ACETATE ION, PTS system glucose-specific EIICB component, Putative NAGC-like transcriptional regulator, ... | 著者 | An, Y.J, Jung, H.I, Cha, S.S. | 登録日 | 2007-12-18 | 公開日 | 2008-05-27 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.85 Å) | 主引用文献 | Analyses of Mlc-IIBGlc interaction and a plausible molecular mechanism of Mlc inactivation by membrane sequestration Proc.Natl.Acad.Sci.Usa, 105, 2008
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3BRF
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![BU of 3brf by Molmil](/molmil-images/mine/3brf) | CSL (Lag-1) bound to DNA with Lin-12 RAM peptide, C2221 | 分子名称: | DNA (5'-D(*DAP*DAP*DTP*DCP*DTP*DTP*DTP*DCP*DCP*DCP*DAP*DCP*DAP*DGP*DT)-3'), DNA (5'-D(*DTP*DTP*DAP*DCP*DTP*DGP*DTP*DGP*DGP*DGP*DAP*DAP*DAP*DGP*DA)-3'), Lin-12 and glp-1 phenotype protein 1, ... | 著者 | Wilson, J.J, Kovall, R.A. | 登録日 | 2007-12-21 | 公開日 | 2008-04-01 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2.47 Å) | 主引用文献 | RAM-induced Allostery Facilitates Assembly of a Notch Pathway Active Transcription Complex. J.Biol.Chem., 283, 2008
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8CEO
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3NAU
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![BU of 3nau by Molmil](/molmil-images/mine/3nau) | Crystal structure of ZHX2 HD2 (zinc-fingers and homeoboxes protein 2, homeodomain 2) | 分子名称: | SULFATE ION, Zinc fingers and homeoboxes protein 2 | 著者 | Ren, J, Bird, L.E, Owens, R.J, Stammers, D.K, Oxford Protein Production Facility (OPPF) | 登録日 | 2010-06-02 | 公開日 | 2010-07-07 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Novel structural features in two ZHX homeodomains derived from a systematic study of single and multiple domains Bmc Struct.Biol., 10, 2010
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8A4I
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![BU of 8a4i by Molmil](/molmil-images/mine/8a4i) | Crystal structure of SALL4 zinc finger cluster 4 with AT-rich DNA | 分子名称: | DNA (5'-D(*GP*AP*TP*AP*TP*TP*AP*AP*TP*AP*TP*C)-3'), MAGNESIUM ION, Sal-like protein 4, ... | 著者 | Watson, J.A, Pantier, R, Jayachandran, U, Chhatbar, K, Alexander-Howden, B, Kruusvee, V, Prendecki, M, Bird, A, Cook, A.G. | 登録日 | 2022-06-11 | 公開日 | 2023-01-11 | 最終更新日 | 2024-05-01 | 実験手法 | X-RAY DIFFRACTION (2.76 Å) | 主引用文献 | Structure of SALL4 zinc finger domain reveals link between AT-rich DNA binding and Okihiro syndrome. Life Sci Alliance, 6, 2023
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8AS9
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![BU of 8as9 by Molmil](/molmil-images/mine/8as9) | Crystal structure of the talin-KANK1 complex | 分子名称: | B-cell lymphoma 6 protein, GLYCEROL, KN-motif NCoR1 BBD fusion,Nuclear receptor corepressor 1, ... | 著者 | Zacharchenko, T. | 登録日 | 2022-08-18 | 公開日 | 2023-06-07 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (3.4 Å) | 主引用文献 | The structural basis of the talin-KANK1 interaction that coordinates the actin and microtubule cytoskeletons at focal adhesions. Open Biology, 13, 2023
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3HC6
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![BU of 3hc6 by Molmil](/molmil-images/mine/3hc6) | FXR with SRC1 and GSK088 | 分子名称: | 3-[(5-{[3-(2,6-dichlorophenyl)-5-(1-methylethyl)isoxazol-4-yl]methoxy}-1H-indol-1-yl)methyl]benzoic acid, Bile acid receptor, Nuclear receptor coactivator 1, ... | 著者 | Williams, S.P, Madauss, K.P. | 登録日 | 2009-05-05 | 公開日 | 2009-07-21 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | 主引用文献 | FXR agonist activity of conformationally constrained analogs of GW 4064. Bioorg.Med.Chem.Lett., 19, 2009
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3LM9
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![BU of 3lm9 by Molmil](/molmil-images/mine/3lm9) | Crystal structure of fructokinase with ADP and Fructose bound in the active site | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, SULFATE ION, ZINC ION, ... | 著者 | Nocek, B, Stein, A, Cuff, M, Volkart, L, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | 登録日 | 2010-01-29 | 公開日 | 2010-03-09 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.45 Å) | 主引用文献 | Structural studies of ROK fructokinase YdhR from Bacillus subtilis: insights into substrate binding and fructose specificity. J.Mol.Biol., 406, 2011
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8BOX
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8BOP
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![BU of 8bop by Molmil](/molmil-images/mine/8bop) | LSD1-CoREST in complex with AW4, long soaking | 分子名称: | Lysine-specific histone demethylase 1A, REST corepressor 1, [[(2~{R},3~{S},4~{R},5~{R})-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl] [(2~{R},3~{S},4~{S})-5-[7,8-dimethyl-2,4-bis(oxidanylidene)-5-[3-[4-(3-phenylphenyl)phenyl]propanoyl]-1~{H}-benzo[g]pteridin-10-yl]-2,3,4-tris(oxidanyl)pentyl] hydrogen phosphate | 著者 | Caroli, J, Mattevi, A. | 登録日 | 2022-11-15 | 公開日 | 2024-06-05 | 実験手法 | X-RAY DIFFRACTION (2.74 Å) | 主引用文献 | Distal drug resistance mutations promote covalent inhibitor-adduct Grob fragmentation in LSD1 to be published
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1E91
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![BU of 1e91 by Molmil](/molmil-images/mine/1e91) | Structure of the complex of the Mad1-Sin3B interaction domains | 分子名称: | MAD PROTEIN (MAX DIMERIZER), PAIRED AMPHIPATHIC HELIX PROTEIN SIN3B | 著者 | Spronk, C.A.E.M, Tessari, M, Kaan, A.M, Jansen, J.F.A, Vermeulen, M, Stunnenberg, H.G, Vuister, G.W. | 登録日 | 2000-10-04 | 公開日 | 2000-11-20 | 最終更新日 | 2024-05-15 | 実験手法 | SOLUTION NMR | 主引用文献 | The MAD1-Sin3B Interaction Involves a Novel Helical Fold Nat.Struct.Biol., 7, 2000
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4CRV
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![BU of 4crv by Molmil](/molmil-images/mine/4crv) | Complex of human CNOT9 and CNOT1 including two tryptophans | 分子名称: | CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT 1, CELL DIFFERENTIATION PROTEIN RCD1 HOMOLOG, GLYCEROL, ... | 著者 | Boland, A, Chen, Y, Izaurralde, E, Weichenrieder, O. | 登録日 | 2014-03-01 | 公開日 | 2014-05-07 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | 主引用文献 | A Ddx6-Cnot1 Complex and W-Binding Pockets in Cnot9 Reveal Direct Links between Mirna Target Recognition and Silencing Mol.Cell, 54, 2014
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3VVY
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![BU of 3vvy by Molmil](/molmil-images/mine/3vvy) | Crystal Strucuture of The Ethidium-Bound Form of RamR (Transcriptional Regurator of TetR Family) from Salmonella Typhimurium | 分子名称: | ETHIDIUM, Putative regulatory protein | 著者 | Sakurai, K, Nikaido, E, Nakashima, R, Yamasaki, S, Yamaguchi, A, Nishino, K. | 登録日 | 2012-07-30 | 公開日 | 2013-07-03 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (1.63 Å) | 主引用文献 | The crystal structure of multidrug-resistance regulator RamR with multiple drugs Nat Commun, 4, 2013
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3VVX
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![BU of 3vvx by Molmil](/molmil-images/mine/3vvx) | Crystal Strucuture of RamR (Transcriptional Regurator of TetR Family) from Salmonella Typhimurium | 分子名称: | Putative regulatory protein, SULFATE ION | 著者 | Sakurai, K, Nikaido, E, Nakashima, R, Yamasaki, S, Yamaguchi, A, Nishino, K. | 登録日 | 2012-07-30 | 公開日 | 2013-07-03 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | 主引用文献 | The crystal structure of multidrug-resistance regulator RamR with multiple drugs Nat Commun, 4, 2013
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3VW1
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![BU of 3vw1 by Molmil](/molmil-images/mine/3vw1) | Crystal Strucuture of the Crystal Violet-Bound Form of RamR (Transcriptional Regurator of TetR Family) from Salmonella Typhimurium | 分子名称: | CHLORIDE ION, CRYSTAL VIOLET, Putative regulatory protein, ... | 著者 | Sakurai, K, Yamasaki, S, Nakashima, R, Nikaido, E, Yamaguchi, A, Nishino, K. | 登録日 | 2012-07-30 | 公開日 | 2013-07-03 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (2.21 Å) | 主引用文献 | The crystal structure of multidrug-resistance regulator RamR with multiple drugs Nat Commun, 4, 2013
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3VK0
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![BU of 3vk0 by Molmil](/molmil-images/mine/3vk0) | Crystal Structure of hypothetical transcription factor NHTF from Neisseria | 分子名称: | Transcriptional regulator | 著者 | Wang, H.-C, Ko, T.-P, Wu, M.-L, Wu, H.-J, Ku, S.-C, Wang, A.H.-J. | 登録日 | 2011-11-01 | 公開日 | 2012-03-14 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.88 Å) | 主引用文献 | Neisseria conserved protein DMP19 is a DNA mimic protein that prevents DNA binding to a hypothetical nitrogen-response transcription factor Nucleic Acids Res., 2012
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3VW0
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![BU of 3vw0 by Molmil](/molmil-images/mine/3vw0) | Crystal Structure of The Dequalinum-bound Form of RamR (Transcriptional Regulator of TetR Family) From Salmonella Typhimurium | 分子名称: | DEQUALINIUM, Putative regulatory protein, SULFATE ION | 著者 | Sakurai, K, Yamasaki, S, Nakashima, R, Nikaido, E, Yamaguchi, A, Nishino, K. | 登録日 | 2012-07-30 | 公開日 | 2013-07-03 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | The crystal structure of multidrug-resistance regulator RamR with multiple drugs Nat Commun, 4, 2013
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4CRW
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![BU of 4crw by Molmil](/molmil-images/mine/4crw) | Complex of human DDX6 (RECA-C) and CNOT1 (MIF4G) | 分子名称: | CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT 1, GLYCEROL, PROBABLE ATP-DEPENDENT RNA HELICASE DDX6 | 著者 | Chen, Y, Boland, A, Izaurralde, E, Weichenrieder, O. | 登録日 | 2014-03-01 | 公開日 | 2014-05-07 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | 主引用文献 | A Ddx6-Cnot1 Complex and W-Binding Pockets in Cnot9 Reveal Direct Links between Mirna Target Recognition and Silencing Mol.Cell, 54, 2014
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3VOD
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5UC1
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![BU of 5uc1 by Molmil](/molmil-images/mine/5uc1) | Structural Analysis of Glucocorticoid Receptor beta Ligand Binding Domain Complexed with Glucocorticoid Antagonist RU-486: Implication of Helix 12 in Antagonism | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, 1,2-ETHANEDIOL, 11-(4-DIMETHYLAMINO-PHENYL)-17-HYDROXY-13-METHYL-17-PROP-1-YNYL-1,2,6,7,8,11,12,13,14,15,16,17-DODEC AHYDRO-CYCLOPENTA[A]PHENANTHREN-3-ONE, ... | 著者 | Pedersen, L.C, Min, J. | 登録日 | 2016-12-21 | 公開日 | 2017-12-27 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.351 Å) | 主引用文献 | Probing Dominant Negative Behavior of Glucocorticoid Receptor beta through a Hybrid Structural and Biochemical Approach. Mol. Cell. Biol., 2018
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4CRU
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![BU of 4cru by Molmil](/molmil-images/mine/4cru) | Complex of human CNOT9 and CNOT1 including one tryptophan | 分子名称: | CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT 1, CELL DIFFERENTIATION PROTEIN RCD1 HOMOLOG, GLYCEROL | 著者 | Chen, Y, Boland, A, Izaurralde, E, Weichenrieder, O. | 登録日 | 2014-03-01 | 公開日 | 2014-05-07 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | 主引用文献 | A Ddx6-Cnot1 Complex and W-Binding Pockets in Cnot9 Reveal Direct Links between Mirna Target Recognition and Silencing Mol.Cell, 54, 2014
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3HC5
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![BU of 3hc5 by Molmil](/molmil-images/mine/3hc5) | FXR with SRC1 and GSK826 | 分子名称: | 3-(6-{[3-(2,6-dichlorophenyl)-5-(1-methylethyl)isoxazol-4-yl]methoxy}-1-benzothiophen-2-yl)benzoic acid, Bile acid receptor, Nuclear receptor coactivator 1, ... | 著者 | Williams, S.P, Madauss, K.P. | 登録日 | 2009-05-05 | 公開日 | 2009-07-21 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | FXR agonist activity of conformationally constrained analogs of GW 4064. Bioorg.Med.Chem.Lett., 19, 2009
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