8A4I

Crystal structure of SALL4 zinc finger cluster 4 with AT-rich DNA

Summary for 8A4I

• Entry DOI: 10.2210/pdb8a4i/pdb
• Descriptor: Sal-like protein 4, DNA (5'-D(*GP*AP*TP*AP*TP*TP*AP*AP*TP*AP*TP*C)-3'), ZINC ION, ... (5 entities in total)
• Functional Keywords: sall4, at-rich dna, okihiro syndrome, transcription factor, stem cell, dna binding protein
• Biological source: Mus musculus (house mouse); More
• Total number of polymer chains: 12
• Total formula weight: 63141.39

Authors

Watson, J.A.,Pantier, R.,Jayachandran, U.,Chhatbar, K.,Alexander-Howden, B.,Kruusvee, V.,Prendecki, M.,Bird, A.,Cook, A.G. (deposition date: 2022-06-11, release date: 2023-01-11, Last modification date: 2023-01-25)

• Primary citation: Watson, J.A.,Pantier, R.,Jayachandran, U.,Chhatbar, K.,Alexander-Howden, B.,Kruusvee, V.,Prendecki, M.,Bird, A.,Cook, A.G.; Structure of SALL4 zinc finger domain reveals link between AT-rich DNA binding and Okihiro syndrome.; Life Sci Alliance, 6:-, 2023; PubMed: 36635047; DOI: 10.26508/lsa.202201588

Experimental method

X-RAY DIFFRACTION (2.76 Å)