8A4I
Crystal structure of SALL4 zinc finger cluster 4 with AT-rich DNA
Summary for 8A4I
Entry DOI | 10.2210/pdb8a4i/pdb |
Descriptor | Sal-like protein 4, DNA (5'-D(*GP*AP*TP*AP*TP*TP*AP*AP*TP*AP*TP*C)-3'), ZINC ION, ... (5 entities in total) |
Functional Keywords | sall4, at-rich dna, okihiro syndrome, transcription factor, stem cell, dna binding protein |
Biological source | Mus musculus (house mouse) More |
Total number of polymer chains | 12 |
Total formula weight | 63141.39 |
Authors | Watson, J.A.,Pantier, R.,Jayachandran, U.,Chhatbar, K.,Alexander-Howden, B.,Kruusvee, V.,Prendecki, M.,Bird, A.,Cook, A.G. (deposition date: 2022-06-11, release date: 2023-01-11, Last modification date: 2024-05-01) |
Primary citation | Watson, J.A.,Pantier, R.,Jayachandran, U.,Chhatbar, K.,Alexander-Howden, B.,Kruusvee, V.,Prendecki, M.,Bird, A.,Cook, A.G. Structure of SALL4 zinc finger domain reveals link between AT-rich DNA binding and Okihiro syndrome. Life Sci Alliance, 6:-, 2023 Cited by PubMed: 36635047DOI: 10.26508/lsa.202201588 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.76 Å) |
Structure validation
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