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8BOX

LSD1-CoREST in complex with AW4 and SNAG peptide

Summary for 8BOX
Entry DOI10.2210/pdb8box/pdb
DescriptorLysine-specific histone demethylase 1A, REST corepressor 1, Zinc finger protein SNAI1, ... (4 entities in total)
Functional Keywordsdemethylase, histone, splicing, epigenetics, oxidoreductase
Biological sourceHomo sapiens (human)
More
Total number of polymer chains3
Total formula weight113685.64
Authors
Caroli, J.,Mattevi, A. (deposition date: 2022-11-15, release date: 2024-06-05)
Primary citationCaroli, J.,Mattevi, A.
Distal drug resistance mutations promote covalent inhibitor-adduct Grob fragmentation in LSD1
to be published,
Experimental method
X-RAY DIFFRACTION (2.82 Å)
Structure validation

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PDB entries from 2024-11-06

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