2PTK
 
 | | CHICKEN SRC TYROSINE KINASE | | 分子名称: | TYROSINE-PROTEIN KINASE TRANSFORMING PROTEIN SRC | | 著者 | Williams, J.C, Wierenga, R. | | 登録日 | 1997-06-17 | | 公開日 | 1997-12-24 | | 最終更新日 | 2018-04-11 | | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | | 主引用文献 | The 2.35 A crystal structure of the inactivated form of chicken Src: a dynamic molecule with multiple regulatory interactions
J.Mol.Biol., 274, 1997
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2PVX
 | | NMR and X-ray Analysis of Structural Additivity in Metal Binding Site-Swapped Hybrids of Rubredoxin | | 分子名称: | Rubredoxin, ZINC ION | | 著者 | Wang, L, LeMaster, D.M, Hernandez, G, Li, H. | | 登録日 | 2007-05-10 | | 公開日 | 2007-12-18 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (1.04 Å) | | 主引用文献 | NMR and X-ray analysis of structural additivity in metal binding site-swapped hybrids of rubredoxin
Bmc Struct.Biol., 7, 2007
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2PX1
 | | crystal structure of the complex of bovine lactoferrin C-lobe with Ribose at 2.5 A resolution | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CARBONATE ION, FE (III) ION, ... | | 著者 | Mir, R, Vikram, G, Sinha, M, Sharma, S, Kaur, P, Singh, T.P. | | 登録日 | 2007-05-14 | | 公開日 | 2007-05-29 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | crystal structure of the complex of bovine lactoferrin C-lobe with Ribose at 2.5 A resolution
To be Published
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2PJ8
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2PGI
 | | THE CRYSTAL STRUCTURE OF PHOSPHOGLUCOSE ISOMERASE-AN ENZYME WITH AUTOCRINE MOTILITY FACTOR ACTIVITY IN TUMOR CELLS | | 分子名称: | PHOSPHOGLUCOSE ISOMERASE | | 著者 | Sun, Y.-J, Chou, C.-C, Chen, W.-S, Meng, M, Hsiao, C.-D. | | 登録日 | 1998-10-27 | | 公開日 | 1999-06-15 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | The crystal structure of a multifunctional protein: phosphoglucose isomerase/autocrine motility factor/neuroleukin.
Proc.Natl.Acad.Sci.USA, 96, 1999
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2PQS
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2PI4
 | | T7RNAP complexed with a phi10 protein and initiating GTPs. | | 分子名称: | 3'-DEOXY-GUANOSINE-5'-TRIPHOSPHATE, 5'-D(*CP*TP*TP*CP*CP*TP*AP*TP*AP*GP*TP*GP*AP*GP*TP*CP*GP*TP*AP*TP*TP*A)-3', 5'-D(*TP*AP*AP*TP*AP*CP*GP*AP*CP*TP*CP*AP*CP*T)-3', ... | | 著者 | Kennedy, W.P, Momand, J.R, Yin, Y.W. | | 登録日 | 2007-04-12 | | 公開日 | 2007-06-19 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Mechanism for de novo RNA synthesis and initiating nucleotide specificity by t7 RNA polymerase.
J.Mol.Biol., 370, 2007
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2PJA
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2PJO
 | | Ricin a-chain (recombinant) complex with n-methylurea | | 分子名称: | N-METHYLUREA, Ricin (EC 3.2.2.22), SULFATE ION | | 著者 | Carra, J.H, Mchugh, C.A, Mulligan, S, Machiesky, L.M, Millard, C.B. | | 登録日 | 2007-04-16 | | 公開日 | 2007-11-20 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Fragment-based identification of determinants of conformational and spectroscopic change at the ricin active site.
Bmc Struct.Biol., 7, 2007
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2Q1J
 | | The discovery of glycine and related amino acid-based factor xa inhibitors | | 分子名称: | 1-(butyl{[(4-chlorophenyl)amino]carbonyl}amino)-N-[3-fluoro-2'-(methylsulfonyl)biphenyl-4-yl]cyclopropanecarboxamide, Activated factor Xa heavy chain (EC 3.4.21.6), CALCIUM ION, ... | | 著者 | Kohrt, J.T, Filipski, K.J, Cody, W.L, Bigge, C.F, Zhang, E, Finzel, B.C. | | 登録日 | 2007-05-24 | | 公開日 | 2007-08-14 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | The Discovery of Glycine and Related Amino Acid-Based Factor Xa Inhibitors
BIOORG.MED.CHEM., 14, 2006
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2Q70
 | | Estrogen receptor alpha ligand-binding domain complxed to a benzopyran ligand | | 分子名称: | (3AS,4R,9BR)-2,2-DIFLUORO-4-(4-HYDROXYPHENYL)-1,2,3,3A,4,9B-HEXAHYDROCYCLOPENTA[C]CHROMEN-8-OL, Estrogen receptor | | 著者 | Wang, Y. | | 登録日 | 2007-06-05 | | 公開日 | 2007-08-07 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | Benzopyrans as selective estrogen receptor beta agonists (SERBAs). Part 3: synthesis of cyclopentanone and cyclohexanone intermediates for C-ring modification.
Bioorg.Med.Chem.Lett., 17, 2007
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2Q9B
 | | Structure of FTSY:GMPPNP Complex | | 分子名称: | 1,2-ETHANEDIOL, Cell division protein ftsY, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, ... | | 著者 | Reyes, C.L, Stroud, R.M. | | 登録日 | 2007-06-12 | | 公開日 | 2007-07-03 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | X-ray Structures of the Signal Recognition Particle Receptor Reveal Targeting Cycle Intermediates.
Plos One, 2, 2007
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2PV0
 | | DNA methyltransferase 3 like protein (DNMT3L) | | 分子名称: | DNA (cytosine-5)-methyltransferase 3-like, ZINC ION | | 著者 | Cheng, X. | | 登録日 | 2007-05-09 | | 公開日 | 2007-08-14 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | | 主引用文献 | DNMT3L connects unmethylated lysine 4 of histone H3 to de novo methylation of DNA.
Nature, 448, 2007
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2Q2J
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2Q9I
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2Q7T
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2Q9G
 | | Crystal structure of human cytochrome P450 46A1 | | 分子名称: | Cytochrome P450 46A1, GLYCEROL, PROTOPORPHYRIN IX CONTAINING FE | | 著者 | White, M.A, Mast, N.V, Johnson, E.F, Stout, C.D, Pikuleva, I.A. | | 登録日 | 2007-06-12 | | 公開日 | 2008-06-17 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Crystal structures of substrate-bound and substrate-free cytochrome P450 46A1, the principal cholesterol hydroxylase in the brain.
Proc.Natl.Acad.Sci.Usa, 105, 2008
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2OAH
 | | Crystal Structure of Human Beta Secretase Complexed with inhibitor | | 分子名称: | Beta-secretase 1, N-[(1S,2S)-2-AMINO-1-(3-THIENYLMETHYL)HEXYL]-2-({[(1S,2S)-2-METHYLCYCLOPROPYL]METHYL}AMINO)-6-[METHYL(METHYLSULFONYL)AMINO]ISONICOTINAMIDE | | 著者 | Munshi, S. | | 登録日 | 2006-12-15 | | 公開日 | 2007-08-14 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Discovery and SAR of isonicotinamide BACE-1 inhibitors that bind beta-secretase in a N-terminal 10s-loop down conformation.
Bioorg.Med.Chem.Lett., 17, 2007
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2OIH
 | | Hepatitis Delta Virus gemonic ribozyme precursor with C75U mutation and bound to monovalent cation Tl+ | | 分子名称: | HDV ribozyme, THALLIUM (I) ION, U1 small nuclear ribonucleoprotein A | | 著者 | Ke, A, Ding, F, Batchelor, J.D, Doudna, J.A. | | 登録日 | 2007-01-11 | | 公開日 | 2007-03-27 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Structural roles of monovalent cations in the HDV ribozyme.
Structure, 15, 2007
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2OJ3
 | | Hepatitis Delta Virus ribozyme precursor structure, with C75U mutation, bound to Tl+ and cobalt hexammine (Co(NH3)63+) | | 分子名称: | COBALT HEXAMMINE(III), HDV RIBOZYME, THALLIUM (I) ION, ... | | 著者 | Ke, A, Ding, F, Batchelor, J.D, Doudna, J.A. | | 登録日 | 2007-01-12 | | 公開日 | 2007-03-27 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | Structural roles of monovalent cations in the HDV ribozyme.
Structure, 15, 2007
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2NSI
 | | HUMAN INDUCIBLE NITRIC OXIDE SYNTHASE, ZN-FREE, SEITU COMPLEX | | 分子名称: | 5,6,7,8-TETRAHYDROBIOPTERIN, ETHYLISOTHIOUREA, PROTEIN (NITRIC OXIDE SYNTHASE), ... | | 著者 | Li, H, Raman, C.S, Glaser, C.B, Blasko, E, Young, T.A, Parkinson, J.F, Whitlow, M, Poulos, T.L. | | 登録日 | 1999-01-11 | | 公開日 | 2000-01-07 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Crystal structures of zinc-free and -bound heme domain of human inducible nitric-oxide synthase. Implications for dimer stability and comparison with endothelial nitric-oxide synthase.
J.Biol.Chem., 274, 1999
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2OGJ
 | | Crystal structure of a dihydroorotase | | 分子名称: | Dihydroorotase, IMIDAZOLE, ZINC ION | | 著者 | Sugadev, R, Kumaran, D, Burley, S.K, Swaminathan, S, New York SGX Research Center for Structural Genomics (NYSGXRC) | | 登録日 | 2007-01-05 | | 公開日 | 2007-02-20 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (2.62 Å) | | 主引用文献 | Crystal structure of a dihydroorotase
To be Published
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2NVB
 | | Contribution of Pro275 to the Thermostability of the Alcohol Dehydrogenases (ADHs) | | 分子名称: | NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, NADP-dependent alcohol dehydrogenase, ZINC ION | | 著者 | Goihberg, E, Tel-Or, S, Peretz, M, Frolow, F, Dym, O, Burstein, Y, Israel Structural Proteomics Center (ISPC) | | 登録日 | 2006-11-12 | | 公開日 | 2007-11-13 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Thermal stabilization of the protozoan Entamoeba histolytica alcohol dehydrogenase by a single proline substitution
Proteins, 72, 2008
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2NWN
 | | New Pharmacophore for Serine Protease Inhibition Revealed by Crystal Structure of Human Urokinase-type Plasminogen Activator Complexed with a Cyclic Peptidyl Inhibitor, upain-1 | | 分子名称: | Plasminogen activator, urokinase, upain-1 | | 著者 | Zhao, G, Yuan, C, Wind, T, Andreasen, P.A, Huang, Z, Huang, M, Structural Genomics Consortium (SGC) | | 登録日 | 2006-11-16 | | 公開日 | 2007-10-16 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | | 主引用文献 | Structural basis of specificity of a peptidyl urokinase inhibitor, upain-1
J.Struct.Biol., 160, 2007
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2O51
 | | Crystal structure of bovine C-lobe with fructose at 3.0 A resolution | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CARBONATE ION, FE (III) ION, ... | | 著者 | Mir, R, Ethayathulla, A.S, Sinha, M, Singh, N, Sharma, S, Singh, T.P. | | 登録日 | 2006-12-05 | | 公開日 | 2007-01-02 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Crystal structure of bovine C-lobe with fructose at 3.0 A resolution
To be Published
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