2PJ8

CRYSTAL STRUCTURE OF ACTIVATED PORCINE PANCREATIC CARBOXYPEPTIDASE B 2-(3-Aminomethyl-phenyl)-3-{[(R)-1-(biphenyl-4-sulfonylamino)-2-methyl-propyl]-hydroxy-phosphinoyl}-propionic acid COMPLEX

Summary for 2PJ8

Entry DOI	10.2210/pdb2pj8/pdb
Related	1Z5R 1ZG7 1ZG8 1ZG9 2PIY 2PIZ 2PJ0 2PJ1 2PJ2 2PJ3 2PJ4 2PJ5 2PJ6 2PJ7 2PJ9 2PJA 2PJB 2PJC
Descriptor	Carboxypeptidase B, ZINC ION, (2S)-2-[3-(AMINOMETHYL)PHENYL]-3-[(R)-{(1R)-1-[(BIPHENYL-4-YLSULFONYL)AMINO]-2-METHYLPROPYL}(HYDROXY)PHOSPHORYL]PROPANOIC ACID, ... (4 entities in total)
Functional Keywords	carboxypeptidase b, exopeptidase, phosphinate based inhibitor, hydrolase
Biological source	Sus scrofa (pig)
Cellular location	Secreted: P09955
Total number of polymer chains	3
Total formula weight	106007.52
Authors	Adler, M.,Whitlow, M. (deposition date: 2007-04-15, release date: 2008-01-22, Last modification date: 2023-08-30)
Primary citation	Adler, M.,Buckman, B.,Bryant, J.,Chang, Z.,Chu, K.,Emayan, K.,Hrvatin, P.,Islam, I.,Morser, J.,Sukovich, D.,West, C.,Yuan, S.,Whitlow, M. Structures of potent selective peptide mimetics bound to carboxypeptidase B. Acta Crystallogr.,Sect.D, 64:149-157, 2008 Cited by PubMed: 18219114 DOI: 10.1107/S0907444907057228 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.7 Å)

Structure validation