PDB: 45176 件ウェブページステータス検索Chemie searchBIRD

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3KSF	structure of fRMsr of Staphylococcus aureus (reduced form) 分子名称: DI(HYDROXYETHYL)ETHER, Putative uncharacterized protein 著者 Bong, S.M, Chi, Y.M. 登録日 2009-11-23 公開日 2010-05-26 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 structure of fRMsr of Staphylococcus aureus To be Published
3KYG	Crystal structure of VCA0042 (L135R) complexed with c-di-GMP 分子名称: GUANOSINE-5'-MONOPHOSPHATE, Putative uncharacterized protein VCA0042 著者 Ryu, K.S, Ko, J, Kim, H, Choi, B.S. 登録日 2009-12-06 公開日 2010-04-14 最終更新日 2024-05-29 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Structure of PP4397 Reveals the Molecular Basis for Different c-di-GMP Binding Modes by Pilz Domain Proteins. J.Mol.Biol., 398, 2010
3KLG	Crystal structure of AZT-resistant HIV-1 Reverse Transcriptase crosslinked to pre-translocation AZTMP-Terminated DNA (COMPLEX N) 分子名称: DNA (5'-D(*A*CP*AP*GP*TP*CP*CP*CP*TP*GP*TP*TP*CP*GP*GP*(MRG)P*CP*GP*CP*CP*AP*(ATM))-3'), DNA (5'-D(*AP*T*GP*CP*AP*TP*GP*GP*CP*GP*CP*CP*CP*GP*AP*AP*CP*AP*GP*GP*GP*AP*CP*TP*GP*TP*G)-3'), Reverse transcriptase/ribonuclease H, ... 著者 Tu, X, Sarafianos, S.G, Arnold, E. 登録日 2009-11-07 公開日 2010-09-22 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (3.65 Å) 主引用文献 Structural basis of HIV-1 resistance to AZT by excision. Nat.Struct.Mol.Biol., 17, 2010
3KLH	Crystal structure of AZT-Resistant HIV-1 Reverse Transcriptase crosslinked to post-translocation AZTMP-Terminated DNA (COMPLEX P) 分子名称: DNA (5'-D(*AP*CP*AP*GP*TP*CP*CP*CP*TP*GP*TP*TP*CP*GP*GP*(MRG)P*CP*GP*CP*CP*(ATM))-3'), DNA (5'-D(*AP*T*GP*CP*TP*AP*GP*GP*CP*GP*CP*CP*CP*GP*AP*AP*CP*AP*GP*GP*GP*AP*CP*TP*GP*TP*G)-3'), MAGNESIUM ION, ... 著者 Tu, X, Sarafianos, S.G, Arnold, E. 登録日 2009-11-07 公開日 2010-09-22 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Structural basis of HIV-1 resistance to AZT by excision. Nat.Struct.Mol.Biol., 17, 2010
3LML	Crystal Structure of the sheath tail protein Lin1278 from Listeria innocua, Northeast Structural Genomics Consortium Target LkR115 分子名称: Lin1278 protein 著者 Forouhar, F, Neely, H, Seetharaman, J, Mao, M, Xiao, R, Patel, D.J, Ciccosanti, C, Wang, H, Everett, J.K, Nair, R, Acton, T.B, Rost, B, Montelione, G.T, Hunt, J.F, Tong, L, Northeast Structural Genomics Consortium (NESG) 登録日 2010-01-31 公開日 2010-03-09 最終更新日 2019-07-17 実験手法 X-RAY DIFFRACTION (3.3 Å) 主引用文献 Northeast Structural Genomics Consortium Target LkR115 To be Published
3LNK	Structure of BACE bound to SCH743813 分子名称: Beta-secretase 1, L(+)-TARTARIC ACID, N'-{(1S,2S)-1-(3,5-difluorobenzyl)-2-hydroxy-2-[(2R)-4-(phenylcarbonyl)piperazin-2-yl]ethyl}-5-methyl-N,N-dipropylbenzene-1,3-dicarboxamide 著者 Orth, P, Cumming, J. 登録日 2010-02-02 公開日 2010-04-14 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Piperazine sulfonamide BACE1 inhibitors: design, synthesis, and in vivo characterization. Bioorg.Med.Chem.Lett., 20, 2010
3LP7	Crystal structure of Human Arginase I in complex with inhibitor N(omega)-hydroxy-L-arginine (NOHA), 2.04A Resolution 分子名称: Arginase-1, MANGANESE (II) ION, N-OMEGA-HYDROXY-L-ARGININE 著者 Di Costanzo, L, Christianson, D.W. 登録日 2010-02-04 公開日 2010-02-23 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.04 Å) 主引用文献 Inhibition of human arginase I by substrate and product analogues. Arch.Biochem.Biophys., 496, 2010
3LPL	E. coli pyruvate dehydrogenase complex E1 component E571A mutant 分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, MAGNESIUM ION, PHOSPHATE ION, ... 著者 Furey, W. 登録日 2010-02-05 公開日 2010-03-02 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Communication between thiamin cofactors in the Escherichia coli pyruvate dehydrogenase complex E1 component active centers: evidence for a "direct pathway" between the 4'-aminopyrimidine N1' atoms. J.Biol.Chem., 285, 2010
3LQJ	Crystal structure of MLL1 PHD3-Bromo complexed with H3(1-9)K4me3 peptide 分子名称: Histone H3, MLL1 PHD3-Bromo, ZINC ION 著者 Wang, Z, Patel, D.J. 登録日 2010-02-09 公開日 2010-07-07 最終更新日 2017-07-26 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Pro isomerization in MLL1 PHD3-bromo cassette connects H3K4me readout to CyP33 and HDAC-mediated repression. Cell(Cambridge,Mass.), 141, 2010
3LQI	Crystal structure of MLL1 PHD3-Bromo complexed with H3(1-9)K4me2 peptide 分子名称: Histone H3, MLL1 PHD3-Bromo, ZINC ION 著者 Wang, Z, Patel, D.J. 登録日 2010-02-09 公開日 2010-07-07 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.92 Å) 主引用文献 Pro isomerization in MLL1 PHD3-bromo cassette connects H3K4me readout to CyP33 and HDAC-mediated repression. Cell(Cambridge,Mass.), 141, 2010
3L8V	Crystal structure of the tyrosine kinase domain of the hepatocyte growth factor receptor C-MET in complex with a biarylamine based inhibitor 分子名称: 2-({4-[(2-aminopyridin-4-yl)oxy]-3-fluorophenyl}amino)-N-(2,4-difluorophenyl)pyridine-3-carboxamide, Hepatocyte growth factor receptor 著者 Sack, J. 登録日 2010-01-04 公開日 2010-05-05 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Design, synthesis and structure-activity relationships of novel biarylamine-based Met kinase inhibitors. Bioorg.Med.Chem.Lett., 20, 2010
3LE9	Crystal structure of the catalytic domain of TACE with Indazolinone-phenyl-hydantoin inhibitor 分子名称: (5R)-5-[(5-methoxy-3-oxo-1,3-dihydro-2H-indazol-2-yl)methyl]-5-phenylimidazolidine-2,4-dione, Disintegrin and metalloproteinase domain-containing protein 17, ISOPROPYL ALCOHOL, ... 著者 Orth, P. 登録日 2010-01-14 公開日 2010-12-08 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Biaryl substituted hydantoin compounds as TACE inhibitors. Bioorg.Med.Chem.Lett., 20, 2010
3LCK	THE KINASE DOMAIN OF HUMAN LYMPHOCYTE KINASE (LCK), ACTIVATED FORM (AUTO-PHOSPHORYLATED ON TYR394) 分子名称: PROTO-ONCOGENE TYROSINE-PROTEIN KINASE, SULFATE ION 著者 Yamaguchi, H, Hendrickson, W.A. 登録日 1997-04-08 公開日 1997-12-03 最終更新日 2023-08-09 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Structural basis for activation of human lymphocyte kinase Lck upon tyrosine phosphorylation. Nature, 384, 1996
3LJD	The X-ray structure of zebrafish RNase1 from a new crystal form at pH 4.5 分子名称: ACETATE ION, SULFATE ION, Zebrafish RNase1 著者 Russo Krauss, I, Merlino, A, Mazzarella, L, Sica, F. 登録日 2010-01-26 公開日 2010-12-08 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.38 Å) 主引用文献 A new RNase sheds light on the RNase/angiogenin subfamily from zebrafish. Biochem.J., 433, 2010
3LM6	Crystal Structure of Stage V sporulation protein AD (spoVAD) from Bacillus subtilis, Northeast Structural Genomics Consortium Target SR525 分子名称: Stage V sporulation protein AD 著者 Forouhar, F, Su, M, Seetharaman, J, Fang, F, Xiao, R, Cunningham, K, Ma, L, Wang, D, Everett, J.K, Nair, R, Acton, T.B, Rost, B, Montelione, G.T, Tong, L, Hunt, J.F, Northeast Structural Genomics Consortium (NESG) 登録日 2010-01-29 公開日 2010-02-16 最終更新日 2019-07-17 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Northeast Structural Genomics Consortium Target SR525 To be Published
3MR3	Human DNA polymerase eta - DNA ternary complex with the 3'T of a CPD in the active site (TT1) 分子名称: 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]adenosine, DNA (5'-D(*CP*AP*(TTD)P*AP*TP*GP*AP*CP*GP*CP*T)-3'), DNA (5'-D(*CP*AP*GP*CP*GP*TP*CP*AP*T)-3'), ... 著者 Biertumpfel, C, Zhao, Y, Ramon-Maiques, S, Gregory, M.T, Lee, J.Y, Yang, W. 登録日 2010-04-28 公開日 2010-06-30 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Structure and mechanism of human DNA polymerase eta. Nature, 465, 2010
3VX7	Crystal structure of Kluyveromyces marxianus Atg7NTD-Atg10 complex 分子名称: E1, E2 著者 Yamaguchi, M, Matoba, K, Sawada, R, Fujioka, Y, Nakatogawa, H, Yamamoto, H, Kobashigawa, Y, Hoshida, H, Akada, R, Ohsumi, Y, Noda, N.N, Inagaki, F. 登録日 2012-09-11 公開日 2012-11-14 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (3.2 Å) 主引用文献 Noncanonical recognition and UBL loading of distinct E2s by autophagy-essential Atg7. Nat.Struct.Mol.Biol., 19, 2012
3W1S	Crystal structure of Saccharomyces cerevisiae Atg12-Atg5 conjugate bound to the N-terminal domain of Atg16 分子名称: Autophagy protein 16, Autophagy protein 5, Ubiquitin-like protein ATG12 著者 Noda, N.N, Fujioka, Y, Hanada, T, Ohsumi, Y, Inagaki, F. 登録日 2012-11-20 公開日 2012-12-26 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Structure of the Atg12-Atg5 conjugate reveals a platform for stimulating Atg8-PE conjugation Embo Rep., 14, 2013
3QQK	CDK2 in complex with inhibitor L4 分子名称: 1,2-ETHANEDIOL, Cyclin-dependent kinase 2, [4-amino-2-(prop-2-en-1-ylamino)-1,3-thiazol-5-yl](phenyl)methanone 著者 Betzi, S, Alam, R, Han, H, Becker, A, Schonbrunn, E. 登録日 2011-02-15 公開日 2012-10-31 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.86 Å) 主引用文献 Development of highly potent and selective diaminothiazole inhibitors of cyclin-dependent kinases. J.Med.Chem., 56, 2013
3MR5	Human DNA polymerase eta - DNA ternary complex with a CPD 1bp upstream of the active site (TT3) 分子名称: 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]guanosine, DNA (5'-D(*AP*CP*GP*TP*CP*AP*TP*AP*A)-3'), DNA (5'-D(*TP*AP*AP*CP*(TTD)P*AP*TP*GP*AP*CP*GP*A)-3'), ... 著者 Biertumpfel, C, Zhao, Y, Ramon-Maiques, S, Gregory, M.T, Lee, J.Y, Yang, W. 登録日 2010-04-28 公開日 2010-06-30 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Structure and mechanism of human DNA polymerase eta. Nature, 465, 2010
3VGO	Crystal structure of the N-terminal fragment of Cbl-b 分子名称: E3 ubiquitin-protein ligase CBL-B 著者 Kobashigawa, Y, Noda, N.N, Inagaki, F. 登録日 2011-08-18 公開日 2011-12-14 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 Autoinhibition and phosphorylation-induced activation mechanisms of human cancer and autoimmune disease-related E3 protein Cbl-b Proc.Natl.Acad.Sci.USA, 108, 2011
3VH1	Crystal structure of Saccharomyces cerevisiae Atg7 (1-595) 分子名称: Ubiquitin-like modifier-activating enzyme ATG7, ZINC ION 著者 Noda, N.N, Satoo, K, Inagaki, F. 登録日 2011-08-23 公開日 2011-09-21 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Structural basis of Atg8 activation by a homodimeric E1, Atg7. Mol.Cell, 44, 2011
3MDF	Crystal structure of the RRM domain of Cyclophilin 33 分子名称: Peptidyl-prolyl cis-trans isomerase E 著者 Hom, R.A, Chang, P.Y, Roy, S, Mussleman, C.A, Glass, K.C, Seleznevia, A.I, Gozani, O, Ismagilov, R.F, Cleary, M.L, Kutateladze, T.G. 登録日 2010-03-30 公開日 2010-05-12 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Molecular mechanism of MLL PHD3 and RNA recognition by the Cyp33 RRM domain. J.Mol.Biol., 400, 2010
3VVM	Crystal structure of G52A-P55G mutant of L-serine-O-acetyltransferase found in D-cycloserine biosynthetic pathway 分子名称: Homoserine O-acetyltransferase 著者 Oda, K, Matoba, Y, Kumagai, T, Noda, M, Sugiyama, M. 登録日 2012-07-26 公開日 2013-03-20 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Crystallographic study to determine the substrate specificity of an L-serine-acetylating enzyme found in the D-cycloserine biosynthetic pathway J.Bacteriol., 195, 2013
3VX6	Crystal structure of Kluyveromyces marxianus Atg7NTD 分子名称: E1 著者 Yamaguchi, M, Matoba, K, Sawada, R, Fujioka, Y, Nakatogawa, H, Yamamoto, H, Kobashigawa, Y, Hoshida, H, Akada, R, Ohsumi, Y, Noda, N.N, Inagaki, F. 登録日 2012-09-11 公開日 2012-11-14 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Noncanonical recognition and UBL loading of distinct E2s by autophagy-essential Atg7. Nat.Struct.Mol.Biol., 19, 2012

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