3MR3
Human DNA polymerase eta - DNA ternary complex with the 3'T of a CPD in the active site (TT1)
Summary for 3MR3
Entry DOI | 10.2210/pdb3mr3/pdb |
Related | 3MR2 3MR4 3MR5 3MR6 |
Descriptor | DNA polymerase eta, DNA (5'-D(*CP*AP*(TTD)P*AP*TP*GP*AP*CP*GP*CP*T)-3'), DNA (5'-D(*CP*AP*GP*CP*GP*TP*CP*AP*T)-3'), ... (7 entities in total) |
Functional Keywords | pol eta, polymerase, thymine dimer, cpd, xpv, xeroderma pigmentosum variant, dna damage, transferase-dna complex, transferase/dna |
Biological source | Homo sapiens (human) |
Cellular location | Nucleus: Q9Y253 |
Total number of polymer chains | 3 |
Total formula weight | 56552.47 |
Authors | Biertumpfel, C.,Zhao, Y.,Ramon-Maiques, S.,Gregory, M.T.,Lee, J.Y.,Yang, W. (deposition date: 2010-04-28, release date: 2010-06-30, Last modification date: 2024-02-21) |
Primary citation | Biertumpfel, C.,Zhao, Y.,Kondo, Y.,Ramon-Maiques, S.,Gregory, M.,Lee, J.Y.,Masutani, C.,Lehmann, A.R.,Hanaoka, F.,Yang, W. Structure and mechanism of human DNA polymerase eta. Nature, 465:1044-1048, 2010 Cited by PubMed: 20577208DOI: 10.1038/nature09196 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.75 Å) |
Structure validation
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