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3MR3

Human DNA polymerase eta - DNA ternary complex with the 3'T of a CPD in the active site (TT1)

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
DNA polymerase etapolymer43548617.71UniProt (Q9Y253)
Pfam (PF00817)
Pfam (PF21704)
Pfam (PF11799)
Homo sapiens (human)RAD30 homolog A, Xeroderma pigmentosum variant type protein
2B
(T)
DNA (5'-D(*CP*AP*(TTD)P*AP*TP*GP*AP*CP*GP*CP*T)-3')polymer113637.41
3C
(P)
DNA (5'-D(*CP*AP*GP*CP*GP*TP*CP*AP*T)-3')polymer92715.81
4D, M
(A)
2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]adenosinenon-polymer490.22Chemie (DZ4)
5E, F
(A)
MAGNESIUM IONnon-polymer24.32Chemie (MG)
6G, H, I, J, K...
(A)
GLYCEROLnon-polymer92.16Chemie (GOL)
7N, O, P
(A, T, P)
waterwater18.0431Chemie (HOH)
Sequence modifications
A: 1 - 432 (UniProt: Q9Y253)
PDBExternal DatabaseDetails
Gly -2-expression tag
Pro -1-expression tag
His 0-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains3
Total formula weight54970.9
Non-Polymers*Number of molecules10
Total formula weight1581.6
All*Total formula weight56552.5
*Water molecules are not included.

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PDB entries from 2025-06-25

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