PDB: 9760 件ウェブページステータス検索Chemie searchBIRD

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5BK2	Crystal structure of maltose binding protein in complex with a peristeric synthetic antibody 分子名称: CHLORIDE ION, GLYCEROL, Maltose-binding periplasmic protein, ... 著者 Mukherjee, S, Kossiakoff, A.A. 登録日 2017-09-12 公開日 2018-01-17 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Engineered synthetic antibodies as probes to quantify the energetic contributions of ligand binding to conformational changes in proteins. J. Biol. Chem., 293, 2018
2MPA	BACTERICIDAL ANTIBODY AGAINST NEISSERIA MENINGITIDIS 分子名称: CADMIUM ION, CONJUGATE OF PORA P1.16 PEPTIDE WITH FLUORESCEIN, MN12H2 IGG2A-KAPPA, ... 著者 Van Den Elsen, J.M.H, Herron, J.N, Kroon, J, Gros, P. 登録日 1999-06-09 公開日 1999-06-23 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Bactericidal antibody recognition of a PorA epitope of Neisseria meningitidis: crystal structure of a Fab fragment in complex with a fluorescein-conjugated peptide. Proteins, 29, 1997
2EIZ	Crystal structure of humanized HYHEL-10 fv mutant(HW47Y)-hen lysozyme complex 分子名称: ANTI-LYSOZYME ANTIBODY FV REGION, Lysozyme C 著者 Nakanishi, T, Tsumoto, K, Yokota, A, Kondo, H, Kumagai, I. 登録日 2007-03-14 公開日 2008-03-18 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Critical contribution of VH-VL interaction to reshaping of an antibody: the case of humanization of anti-lysozyme antibody, HyHEL-10 Protein Sci., 17, 2008
2EKS	Crystal structure of humanized HyHEL-10 FV-HEN lysozyme complex 分子名称: ANTI-LYSOZYME ANTIBODY FV REGION, Lysozyme C 著者 Nakanishi, T, Tsumoto, K, Yokota, A, Kondo, H, Kumagai, I. 登録日 2007-03-24 公開日 2008-03-25 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Critical contribution of VH-VL interaction to reshaping of an antibody: the case of humanization of anti-lysozyme antibody, HyHEL-10 Protein Sci., 17, 2008
8DF1	Chi3l1 bound by antibody C59 分子名称: C59 Fab Heavy chain, C59 Fab Light chain, Chitinase-3-like protein 1, ... 著者 Wrapp, D, McLellan, J.S. 登録日 2022-06-21 公開日 2023-03-01 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (3.3 Å) 主引用文献 A novel humanized Chi3l1 blocking antibody attenuates acetaminophen-induced liver injury in mice. Antib Ther, 6, 2023
2J5L	Structure of a Plasmodium falciparum apical membrane antigen 1-Fab F8. 12.19 complex 分子名称: APICAL MEMBRANE ANTIGEN 1, FAB FRAGMENT OF MONOCLONAL ANTIBODY F8.12.19 著者 Igonet, S, Vulliez-Le Normand, B, Faure, G, Riottot, M.M, Kocken, C.H.M, Thomas, A.W, Bentley, G.A. 登録日 2006-09-18 公開日 2007-01-30 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Cross-Reactivity Studies of an Anti-Plasmodium Vivax Apical Membrane Antigen 1 Monoclonal Antibody: Binding and Structural Characterisation. J.Mol.Biol., 366, 2007
7K7H	Density-fitted Model Structure of Antibody Variable Domains of TyTx1 in Complex with PltB pentamer of Typhoid Toxin 分子名称: Fab Heavy Chain Variable Domain, Fab Light Chain Variable Domain, Pertussis like toxin subunit B, ... 著者 Nguyen, T, Feathers, J.R, Fromme, J.C, Song, J. 登録日 2020-09-22 公開日 2021-09-01 最終更新日 2021-09-22 実験手法 ELECTRON MICROSCOPY (3 Å) 主引用文献 The structural basis of Salmonella A 2 B 5 toxin neutralization by antibodies targeting the glycan-receptor binding subunits. Cell Rep, 36, 2021
7K7I	Density-fitted Model Structure of Antibody Variable Domains of TyTx4 in Complex with PltB pentamer of Typhoid Toxin 分子名称: Fab Heavy Chain Variable Domain, Fab Light Chain Variable Domain, Putative pertussis-like toxin subunit 著者 Nguyen, T, Feathers, J.R, Fromme, J.C, Song, J. 登録日 2020-09-22 公開日 2021-09-01 最終更新日 2021-09-22 実験手法 ELECTRON MICROSCOPY (3.13 Å) 主引用文献 The structural basis of Salmonella A 2 B 5 toxin neutralization by antibodies targeting the glycan-receptor binding subunits. Cell Rep, 36, 2021
6MEK	Crystal structure of Hepatitis C virus envelope glycoprotein E2 core in complex with human antibodies HEPC3 and HEPC46 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, E2 GLYCOPROTEIN, ... 著者 Flyak, A.I, Bjorkman, P.J. 登録日 2018-09-06 公開日 2018-11-21 最終更新日 2020-07-29 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 HCV Broadly Neutralizing Antibodies Use a CDRH3 Disulfide Motif to Recognize an E2 Glycoprotein Site that Can Be Targeted for Vaccine Design. Cell Host Microbe, 24, 2018
7Q6C	complement C6 FIM1-2 bound to CP010 antibody 分子名称: ACETATE ION, CP010 heavy chain, CP010 light chain, ... 著者 Olesen, H.G, Andersen, G.R. 登録日 2021-11-06 公開日 2022-05-25 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.29274 Å) 主引用文献 Development, Characterization, and in vivo Validation of a Humanized C6 Monoclonal Antibody that Inhibits the Membrane Attack Complex. J Innate Immun, 2022
8F6L	anti-BTLA monoclonal antibody h25F7 in complex with BTLA 分子名称: B- and T-lymphocyte attenuator, h25F7 Fab heavy chain, h25F7 Fab light chain 著者 Hendle, J, Atwell, S, Lieu, R, Hickey, M, Weichert, K. 登録日 2022-11-16 公開日 2023-05-24 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Epitope topography of agonist antibodies to the checkpoint inhibitory receptor BTLA. Structure, 31, 2023
3DJ9	Crystal Structure of an isolated, unglycosylated antibody CH2 domain 分子名称: Ig gamma-1 chain C region 著者 Prabakaran, P, Vu, B.K, Gan, J, Dimitrov, D.S, Ji, X. 登録日 2008-06-22 公開日 2008-09-16 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Structure of an isolated unglycosylated antibody C(H)2 domain. Acta Crystallogr.,Sect.D, 64, 2008
3BPC	co-crystal structure of S25-2 Fab in complex with 5-deoxy-4-epi-2,3-dehydro Kdo (4.8) Kdo 分子名称: 3,4,5-trideoxy-alpha-D-erythro-oct-3-en-2-ulopyranosonic acid-(2-8)-prop-2-en-1-yl 3-deoxy-alpha-D-manno-oct-2-ulopyranosidonic acid, Fab, antibody fragment (IgG1k), ... 著者 Brooks, C.L, Evans, S.V. 登録日 2007-12-18 公開日 2009-01-13 最終更新日 2020-07-29 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Exploration of specificity in germline monoclonal antibody recognition of a range of natural and synthetic epitopes. J.Mol.Biol., 377, 2008
8DS5	X-ray structure of the MK5890 Fab - CD27 antibody-antigen complex 分子名称: CADMIUM ION, CD27 antigen, MK-5890 Fab heavy chain, ... 著者 Fischmann, T.O. 登録日 2022-07-21 公開日 2022-09-28 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.926 Å) 主引用文献 Preclinical characterization and clinical translation of pharmacodynamic markers for MK-5890: a human CD27 activating antibody for cancer immunotherapy. J Immunother Cancer, 10, 2022
7QF1	Crystal structure of the SARS-CoV-2 RBD in complex with the human antibody CV2.6264 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CV2.6264 heavy chain, CV2.6264 light chain, ... 著者 Fernandez, I, Pederzoli, R, Rey, F.A. 登録日 2021-12-03 公開日 2022-05-18 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Potent human broadly SARS-CoV-2-neutralizing IgA and IgG antibodies effective against Omicron BA.1 and BA.2. J.Exp.Med., 219, 2022
7QF0	Crystal structure of the SARS-CoV-2 RBD in complex with the human antibody CV2.2325 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, CV2.2325 heavy chain, ... 著者 Fernandez, I, Pederzoli, R, Rey, F.A. 登録日 2021-12-03 公開日 2022-05-18 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Potent human broadly SARS-CoV-2-neutralizing IgA and IgG antibodies effective against Omicron BA.1 and BA.2. J.Exp.Med., 219, 2022
7QEZ	Crystal structure of the SARS-CoV-2 RBD in complex with the ultrapotent antibody CV2.1169 and CR3022 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CR3022 heavy chain, CR3022 light chain, ... 著者 Fernandez, I, Rey, F.A. 登録日 2021-12-03 公開日 2022-05-18 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2.89 Å) 主引用文献 Potent human broadly SARS-CoV-2-neutralizing IgA and IgG antibodies effective against Omicron BA.1 and BA.2. J.Exp.Med., 219, 2022
2O5Y	Crystal structure of the 1E9 LeuH47Trp/ArgH100Trp Fab progesterone complex 分子名称: PROGESTERONE, SULFATE ION, chimeric antibody Fab 1E9-DB3 著者 Verdino, P, Wilson, I.A. 登録日 2006-12-06 公開日 2007-12-18 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (2.85 Å) 主引用文献 Closely related antibody receptors exploit fundamentally different strategies for steroid recognition. Proc.Natl.Acad.Sci.Usa, 105, 2008
7PKL	Mechanistic understanding of antibody masking with anti-idiotypic antibody fragments 分子名称: SULFATE ION, trastuzumab Heavy Chain, trastuzumab Light Chain VHH fusion 著者 Hargreaves, D. 登録日 2021-08-25 公開日 2022-09-07 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.35 Å) 主引用文献 Mechanistic insights into the rational design of masked antibodies. Mabs, 14
4RNR	Crystal structure of broadly neutralizing anti-HIV antibody PGT130 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, PGT130 Heavy Chain, PGT130 Light Chain 著者 Kong, L, Wilson, I.A. 登録日 2014-10-24 公開日 2014-11-19 最終更新日 2020-07-29 実験手法 X-RAY DIFFRACTION (2.758 Å) 主引用文献 Two Classes of Broadly Neutralizing Antibodies within a Single Lineage Directed to the High-Mannose Patch of HIV Envelope. J.Virol., 89, 2015
4U7S	Homodimeric Single Domain Antibody (sdAb) against Staphylococcal enterotoxin B (SEB) Crystallized for 5 months 分子名称: SULFATE ION, sdAb A3 著者 Legler, P.M. 登録日 2014-07-31 公開日 2014-09-03 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.07 Å) 主引用文献 Structural and mutational analysis of a monomeric and dimeric form of a single domain antibody with implications for protein misfolding. Proteins, 82, 2014
4KI5	Cystal structure of human factor VIII C2 domain in a ternary complex with murine inhbitory antibodies 3E6 and G99 分子名称: Coagulation factor VIII, MURINE MONOCLONAL 3E6 FAB HEAVY CHAIN, MURINE MONOCLONAL 3E6 FAB LIGHT CHAIN, ... 著者 Walter, J.D, Meeks, S.L, Healey, J.F, Lollar, P, Spiegel, P.C. 登録日 2013-05-01 公開日 2014-01-15 実験手法 X-RAY DIFFRACTION (2.47 Å) 主引用文献 Structure of the factor VIII C2 domain in a ternary complex with 2 inhibitor antibodies reveals classical and nonclassical epitopes. Blood, 122, 2013
7SC1	Structure of the SARS-CoV-2 S 6P trimer in complex with the human neutralizing antibody Fab fragment, R40-1G8 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, R40-1G8 Fab heavy chain, R40-1G8 Fab light chain, ... 著者 Fan, C, Bjorkman, P.J. 登録日 2021-09-26 公開日 2022-02-02 実験手法 ELECTRON MICROSCOPY (3.2 Å) 主引用文献 Discovery of ultrapotent broadly neutralizing antibodies from SARS-CoV-2 elite neutralizers. Cell Host Microbe, 30, 2022
8F9E	Crystal structure of Ky15.2 Fab in complex with circumsporozoite protein KQPA peptide 分子名称: Circumsporozoite protein KQPA peptide, Ky15.2 Antibody, heavy chain, ... 著者 Thai, E, Julien, J.P. 登録日 2022-11-23 公開日 2023-11-01 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (2.95 Å) 主引用文献 Molecular determinants of cross-reactivity and potency by VH3-33 antibodies against the Plasmodium falciparum circumsporozoite protein. Cell Rep, 42, 2023
8F95	Crystal structure of Ky15.2 Fab in complex with circumsporozoite protein DND peptide 分子名称: 1,2-ETHANEDIOL, Circumsporozoite protein DND peptide, Ky15.2 Antibody, ... 著者 Thai, E, Julien, J.P. 登録日 2022-11-23 公開日 2023-11-01 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (2.45 Å) 主引用文献 Molecular determinants of cross-reactivity and potency by VH3-33 antibodies against the Plasmodium falciparum circumsporozoite protein. Cell Rep, 42, 2023

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