4RNR

Crystal structure of broadly neutralizing anti-HIV antibody PGT130

Summary for 4RNR

• Entry DOI: 10.2210/pdb4rnr/pdb
• Descriptor: PGT130 Heavy Chain, PGT130 Light Chain, 2-acetamido-2-deoxy-beta-D-glucopyranose (3 entities in total)
• Functional Keywords: pgt130, pgt 130, immunoglobulin fold, broadly neutralizing antibody, hiv-1 gp120 binding, n-linked glycan, immune system
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 4
• Total formula weight: 97082.40

Authors

Kong, L.,Wilson, I.A. (deposition date: 2014-10-24, release date: 2014-11-19, Last modification date: 2020-07-29)

• Primary citation: Doores, K.J.,Kong, L.,Krumm, S.A.,Le, K.M.,Sok, D.,Laserson, U.,Garces, F.,Poignard, P.,Wilson, I.A.,Burton, D.R.; Two Classes of Broadly Neutralizing Antibodies within a Single Lineage Directed to the High-Mannose Patch of HIV Envelope.; J.Virol., 89:1105-1118, 2015; PubMed: 25378488; DOI: 10.1128/JVI.02905-14

Experimental method

X-RAY DIFFRACTION (2.758 Å)