7Q6C

complement C6 FIM1-2 bound to CP010 antibody

Summary for 7Q6C

• Entry DOI: 10.2210/pdb7q6c/pdb
• Descriptor: Complement component C6, CP010 heavy chain, kappa specific nanobody, ... (6 entities in total)
• Functional Keywords: complement antibody terminal pathway, immune system
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 4
• Total formula weight: 79254.31

Authors

Olesen, H.G.,Andersen, G.R. (deposition date: 2021-11-06, release date: 2022-05-25, Last modification date: 2024-01-31)

• Primary citation: Gytz Olesen, H.,Michailidou, I.,Zelek, W.M.,Vreijling, J.,Ruizendaal, P.,de Klein, F.,Marquart, J.A.,Kuipers, T.B.,Mei, H.,Zhang, Y.,Ahasan, M.,Johnson, K.K.,Wang, Y.,Morgan, B.P.,van Dijk, M.,Fluiter, K.,Andersen, G.R.,Baas, F.; Development, Characterization, and in vivo Validation of a Humanized C6 Monoclonal Antibody that Inhibits the Membrane Attack Complex.; J Innate Immun, :1-21, 2022; PubMed: 35551129; DOI: 10.1159/000524587

Experimental method

X-RAY DIFFRACTION (2.29274 Å)