8F6L

anti-BTLA monoclonal antibody h25F7 in complex with BTLA

Summary for 8F6L

• Entry DOI: 10.2210/pdb8f6l/pdb
• Related: 8F60
• Descriptor: h25F7 Fab heavy chain, h25F7 Fab light chain, B- and T-lymphocyte attenuator, ... (4 entities in total)
• Functional Keywords: monoclonal antibody, complex, immune system
• Biological source: Homo sapiens; More
• Total number of polymer chains: 3
• Total formula weight: 63694.84

Authors

Hendle, J.,Atwell, S.,Lieu, R.,Hickey, M.,Weichert, K. (deposition date: 2022-11-16, release date: 2023-05-24, Last modification date: 2023-10-25)

• Primary citation: Cheung, T.C.,Atwell, S.,Bafetti, L.,Cuenca, P.D.,Froning, K.,Hendle, J.,Hickey, M.,Ho, C.,Huang, J.,Lieu, R.,Lim, S.,Lippner, D.,Obungu, V.,Ward-Kavanagh, L.,Weichert, K.,Ware, C.F.,Vendel, A.C.; Epitope topography of agonist antibodies to the checkpoint inhibitory receptor BTLA.; Structure, 31:958-, 2023; PubMed: 37279757; DOI: 10.1016/j.str.2023.05.011

Experimental method

X-RAY DIFFRACTION (1.85 Å)