7SC1

Structure of the SARS-CoV-2 S 6P trimer in complex with the human neutralizing antibody Fab fragment, R40-1G8

Summary for 7SC1

• Entry DOI: 10.2210/pdb7sc1/pdb
• EMDB information: 25008
• Descriptor: Spike glycoprotein, R40-1G8 Fab heavy chain, R40-1G8 Fab light chain, ... (4 entities in total)
• Functional Keywords: immune system, neutralizing antibody, viral protein, viral protein-immune system complex, viral protein/immune system
• Biological source: Severe acute respiratory syndrome coronavirus 2 (2019-nCoV, SARS-CoV-2); More
• Total number of polymer chains: 9
• Total formula weight: 569034.57

Authors

Fan, C.,Bjorkman, P.J. (deposition date: 2021-09-26, release date: 2022-02-02)

• Primary citation: Vanshylla, K.,Fan, C.,Wunsch, M.,Poopalasingam, N.,Meijers, M.,Kreer, C.,Kleipass, F.,Ruchnewitz, D.,Ercanoglu, M.S.,Gruell, H.,Munn, F.,Pohl, K.,Janicki, H.,Nolden, T.,Bartl, S.,Stein, S.C.,Augustin, M.,Dewald, F.,Gieselmann, L.,Schommers, P.,Schulz, T.F.,Sander, L.E.,Koch, M.,Luksza, M.,Lassig, M.,Bjorkman, P.J.,Klein, F.; Discovery of ultrapotent broadly neutralizing antibodies from SARS-CoV-2 elite neutralizers.; Cell Host Microbe, 30:69-82.e10, 2022; PubMed: 34973165; DOI: 10.1016/j.chom.2021.12.010

Experimental method

ELECTRON MICROSCOPY (3.2 Å)