PDB: 153 件ウェブページステータス検索Chemie searchBIRD

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5YVH	Crystal structure of Karyopherin beta2 in complex with FUS(371-526) 分子名称: RNA-binding protein FUS, Transportin-1 著者 Yoshizawa, T, Fung, H.Y.J, Chook, Y.M. 登録日 2017-11-25 公開日 2018-05-16 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (3.15 Å) 主引用文献 Nuclear Import Receptor Inhibits Phase Separation of FUS through Binding to Multiple Sites. Cell, 173, 2018
8SGH	Cryo-EM structure of Karyopherin-beta2 bound to HNRNPH2 PY-NLS 分子名称: Heterogeneous nuclear ribonucleoprotein H2, N-terminally processed, Transportin-1 著者 Gonzalez, A, Fung, H.Y.J, Chook, Y.M. 登録日 2023-04-12 公開日 2023-06-14 最終更新日 2023-08-16 実験手法 ELECTRON MICROSCOPY (3.17 Å) 主引用文献 A new Karyopherin-beta 2 binding PY-NLS epitope of HNRNPH2 linked to neurodevelopmental disorders. Structure, 31, 2023
2Z5N	Complex of Transportin 1 with hnRNP D NLS 分子名称: Heterogeneous nuclear ribonucleoprotein D0, Transportin-1 著者 Imasaki, T, Shimizu, T, Hashimoto, H, Hidaka, Y, Kose, S, Imamoto, N, Yamada, M, Sato, M. 登録日 2007-07-14 公開日 2007-10-23 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (3.2 Å) 主引用文献 Structural basis for substrate recognition and dissociation by human transportin 1 Mol.Cell, 28, 2007
2Z5O	Complex of Transportin 1 with JKTBP NLS 分子名称: Heterogeneous nuclear ribonucleoprotein D-like, Transportin-1 著者 Imasaki, T, Shimizu, T, Hashimoto, H, Hidaka, Y, Kose, S, Imamoto, N, Yamada, M, Sato, M. 登録日 2007-07-14 公開日 2007-10-23 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (3.2 Å) 主引用文献 Structural basis for substrate recognition and dissociation by human transportin 1 Mol.Cell, 28, 2007
2Q5D	Crystal Structure of Human Importin Beta bound to the Snurportin1 IBB-domain second crystal form 分子名称: Importin beta-1 subunit, Snurportin-1 著者 Mitrousis, G, Cingolani, G. 登録日 2007-05-31 公開日 2008-01-22 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (3.2 Å) 主引用文献 Molecular Basis for the Recognition of Snurportin 1 by Importin {beta}. J.Biol.Chem., 283, 2008
6TVO	Human CRM1-RanGTP in complex with Leptomycin B 分子名称: Exportin-1, GTP-binding nuclear protein Ran, GUANOSINE-5'-TRIPHOSPHATE, ... 著者 Shaikhqasem, A, Ficner, R. 登録日 2020-01-10 公開日 2020-07-08 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (3.201 Å) 主引用文献 Characterization of Inhibition Reveals Distinctive Properties for Human andSaccharomyces cerevisiaeCRM1. J.Med.Chem., 63, 2020
8F0X	Cryo-EM structure of Kap114 bound to H2A-H2B 分子名称: Histone H2A.2, Histone H2B.2, Importin subunit beta-5 著者 Jiou, J, Chook, Y.M. 登録日 2022-11-04 公開日 2023-07-26 最終更新日 2024-06-19 実験手法 ELECTRON MICROSCOPY (3.21 Å) 主引用文献 Mechanism of RanGTP priming H2A-H2B release from Kap114 in an atypical RanGTP•Kap114•H2A-H2B complex. Proc.Natl.Acad.Sci.USA, 120, 2023
4XRK	Crystal Structure of Importin Beta in a Polyethylene Glycol Condition 分子名称: Importin Beta 著者 Tauchert, M.J, Neumann, P, Ficner, R, Dickmanns, A. 登録日 2015-01-21 公開日 2016-01-27 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (3.25 Å) 主引用文献 Impact of the crystallization condition on importin-beta conformation. Acta Crystallogr D Struct Biol, 72, 2016
8F1E	Cryo-EM structure of Kap114 bound to Gsp1 (RanGTP) and H2A-H2B 分子名称: GTP-binding nuclear protein GSP1/CNR1, GUANOSINE-5'-TRIPHOSPHATE, Histone H2A.2, ... 著者 Jiou, J, Chook, Y.M. 登録日 2022-11-04 公開日 2023-07-26 最終更新日 2024-06-19 実験手法 ELECTRON MICROSCOPY (3.28 Å) 主引用文献 Mechanism of RanGTP priming H2A-H2B release from Kap114 in an atypical RanGTP•Kap114•H2A-H2B complex. Proc.Natl.Acad.Sci.USA, 120, 2023
6FVB	Structure of Lph2 , a novel bidirectional nuclear transport receptor in S. cerevisiae 分子名称: Importin beta-like protein KAP120 著者 Vera Rodriguez, A, Huyton, T, Gorlich, D. 登録日 2018-03-01 公開日 2019-09-11 実験手法 X-RAY DIFFRACTION (3.297 Å) 主引用文献 Structure of Lph2 , a novel bidirectional nuclear transport receptor in S. cerevisiae To Be Published
5YU7	CRYSTAL STRUCTURE OF EXPORTIN-5 分子名称: Exportin-5 著者 Yamazawa, R, Jiko, C, Lee, S.J, Yamashita, E. 登録日 2017-11-20 公開日 2018-08-29 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (3.301 Å) 主引用文献 Structural Basis for Selective Binding of Export Cargoes by Exportin-5 Structure, 26, 2018
2X1G	Crystal structure of Importin13 - Mago-Y14 complex 分子名称: CADMUS, PROTEIN MAGO NASHI, RNA-BINDING PROTEIN 8A 著者 Bono, F, Cook, A.G, Gruenwald, M, Ebert, J, Conti, E. 登録日 2009-12-23 公開日 2010-02-16 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (3.35 Å) 主引用文献 Nuclear Import Mechanism of the Ejc Component Mago- Y14 Revealed by Structural Studies of Importin 13. Mol.Cell, 37, 2010
3NC1	Crystal structure of the CRM1-RanGTP complex 分子名称: Exportin-1, GTP-binding nuclear protein Ran, GUANOSINE-5'-TRIPHOSPHATE, ... 著者 Guttler, T, Madl, T, Neumann, P, Deichsel, D, Corsini, L, Monecke, T, Ficner, R, Sattler, M, Gorlich, D. 登録日 2010-06-04 公開日 2010-10-27 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (3.35 Å) 主引用文献 NES consensus redefined by structures of PKI-type and Rev-type nuclear export signals bound to CRM1. Nat.Struct.Mol.Biol., 17, 2010
2Z5J	Free Transportin 1 分子名称: Transportin-1 著者 Imasaki, T, Shimizu, T, Hashimoto, H, Hidaka, Y, Yamada, M, Sato, M. 登録日 2007-07-13 公開日 2007-10-23 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (3.4 Å) 主引用文献 Structural basis for substrate recognition and dissociation by human transportin 1 Mol.Cell, 28, 2007
3NBY	Crystal structure of the PKI NES-CRM1-RanGTP nuclear export complex 分子名称: Exportin-1, GTP-binding nuclear protein Ran, GUANOSINE-5'-TRIPHOSPHATE, ... 著者 Guttler, T, Madl, T, Neumann, P, Deichsel, D, Corsini, L, Monecke, T, Ficner, R, Sattler, M, Gorlich, D. 登録日 2010-06-04 公開日 2010-10-27 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (3.42 Å) 主引用文献 NES consensus redefined by structures of PKI-type and Rev-type nuclear export signals bound to CRM1. Nat.Struct.Mol.Biol., 17, 2010
7UNK	Structure of Importin-4 bound to the H3-H4-ASF1 histone-histone chaperone complex 分子名称: Histone H3, Histone H4, Histone chaperone, ... 著者 Bernardes, N.E, Chook, Y.M, Fung, H.Y.J, Chen, Z, Li, Y. 登録日 2022-04-11 公開日 2022-09-21 最終更新日 2024-06-12 実験手法 ELECTRON MICROSCOPY (3.45 Å) 主引用文献 Structure of IMPORTIN-4 bound to the H3-H4-ASF1 histone-histone chaperone complex. Proc.Natl.Acad.Sci.USA, 119, 2022
8F19	Cryo-EM structure of Kap114 bound to Gsp1 (RanGTP) 分子名称: GTP-binding nuclear protein GSP1/CNR1, GUANOSINE-5'-TRIPHOSPHATE, Importin subunit beta-5, ... 著者 Jiou, J, Chook, Y.M. 登録日 2022-11-04 公開日 2023-07-26 最終更新日 2024-06-19 実験手法 ELECTRON MICROSCOPY (3.49 Å) 主引用文献 Mechanism of RanGTP priming H2A-H2B release from Kap114 in an atypical RanGTP•Kap114•H2A-H2B complex. Proc.Natl.Acad.Sci.USA, 120, 2023
3ZJY	Crystal Structure of Importin 13 - RanGTP - eIF1A complex 分子名称: EUKARYOTIC TRANSLATION INITIATION FACTOR 1A, X-CHROMOSOMAL, GTP-BINDING NUCLEAR PROTEIN RAN, ... 著者 Gruenwald, M, Lazzaretti, D, Bono, F. 登録日 2013-01-21 公開日 2013-04-10 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (3.6 Å) 主引用文献 Structural Basis for the Nuclear Export Activity of Importin13. Embo J., 32, 2013
7VPW	Crystal structure of Transportin-1 in complex with BAP1 PY-NLS (residues 706-724) 分子名称: BRCA1-associated protein 1 (BAP1), Transportin-1 著者 Yang, T.J, Hsu, S.T.D. 登録日 2021-10-18 公開日 2022-04-20 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (3.76 Å) 主引用文献 Tumor suppressor BAP1 nuclear import is governed by transportin-1. J.Cell Biol., 221, 2022
8F7A	Cryo-EM structure of Importin-9 bound to RanGTP 分子名称: GTP-binding nuclear protein GSP1/CNR1, GUANOSINE-5'-TRIPHOSPHATE, Importin-9, ... 著者 Bernardes, N.E, Chook, Y.M. 登録日 2022-11-18 公開日 2023-07-26 最終更新日 2024-05-22 実験手法 ELECTRON MICROSCOPY (3.78 Å) 主引用文献 Mechanism of RanGTP priming H2A-H2B release from Kap114 in an atypical RanGTP•Kap114•H2A-H2B complex. Proc.Natl.Acad.Sci.USA, 120, 2023
8GCN	CRYO-EM STRUCTURE OF IMPORTIN ALPHA1/BETA HETERODIMER 分子名称: Importin subunit alpha-1, Importin subunit beta-1 著者 Ko, Y, Cingolani, G. 登録日 2023-03-02 公開日 2024-03-06 実験手法 ELECTRON MICROSCOPY (3.95 Å) 主引用文献 CRYO-EM STRUCTURE OF IMPORTIN ALPHA1/BETA HETERODIMER To Be Published
8H5B	The cryo-EM structure of nuclear transport receptor Kap114p complex with yeast TATA-box binding protein 分子名称: Importin subunit beta-5, TATA-box-binding protein 著者 Hsia, K.C, Liao, C.C, Wang, C.H, Wu, Y.M. 登録日 2022-10-12 公開日 2023-09-20 実験手法 ELECTRON MICROSCOPY (4.03 Å) 主引用文献 Structural convergence endows nuclear transport receptor Kap114p with a transcriptional repressor function toward TATA-binding protein. Nat Commun, 14, 2023
5YVG	Crystal structure of Karyopherin beta2 in complex with FUS(full length) 分子名称: RNA-binding protein FUS, Transportin-1 著者 Yoshizawa, T, Fung, H.Y.J, Chook, Y.M. 登録日 2017-11-25 公開日 2018-05-16 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (4.05 Å) 主引用文献 Nuclear Import Receptor Inhibits Phase Separation of FUS through Binding to Multiple Sites. Cell, 173, 2018
4BSN	Crystal structure of the Nuclear Export Receptor CRM1 (exportin-1) lacking the C-terminal helical extension at 4.1A 分子名称: EXPORTIN-1 著者 Dian, C, Bernaudat, F, Langer, K, Oliva, M.F, Fornerod, M, Schoehn, G, Muller, C.W, Petosa, C. 登録日 2013-06-11 公開日 2013-07-31 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (4.1 Å) 主引用文献 Structure of a Truncation Mutant of the Nuclear Export Factor Crm1 Provides Insights Into the Auto-Inhibitory Role of its C-Terminal Helix. Structure, 21, 2013
4BSM	Crystal structure of the Nuclear Export Receptor CRM1 (exportin-1) lacking the C-terminal helical extension at 4.5A 分子名称: EXPORTIN-1 著者 Dian, C, Bernaudat, F, Langer, K, Oliva, M.F, Fornerod, M, Schoehn, G, Muller, C.W, Petosa, C. 登録日 2013-06-10 公開日 2013-07-31 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (4.5 Å) 主引用文献 Structure of a Truncation Mutant of the Nuclear Export Factor Crm1 Provides Insights Into the Auto-Inhibitory Role of its C-Terminal Helix. Structure, 21, 2013

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