7VPW

Crystal structure of Transportin-1 in complex with BAP1 PY-NLS (residues 706-724)

Summary for 7VPW

Entry DOI	10.2210/pdb7vpw/pdb
Descriptor	BRCA1-associated protein 1 (BAP1), Transportin-1 (2 entities in total)
Functional Keywords	transportin-1, brca1-associated protein 1, bap1, nuclear import, py-nls, deubiquitinase, dub, protein transport
Biological source	Homo sapiens (human) More
Total number of polymer chains	2
Total formula weight	100969.51
Authors	Yang, T.J.,Hsu, S.T.D. (deposition date: 2021-10-18, release date: 2022-04-20, Last modification date: 2023-11-29)
Primary citation	Yang, T.J.,Li, T.N.,Huang, R.S.,Pan, M.Y.,Lin, S.Y.,Lin, S.,Wu, K.P.,Wang, L.H.,Hsu, S.D. Tumor suppressor BAP1 nuclear import is governed by transportin-1. J.Cell Biol., 221:-, 2022 Cited by PubMed: 35446349 DOI: 10.1083/jcb.202201094 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3.76 Å)

Structure validation