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5YVH

Crystal structure of Karyopherin beta2 in complex with FUS(371-526)

Summary for 5YVH
Entry DOI10.2210/pdb5yvh/pdb
DescriptorTransportin-1, RNA-binding protein FUS (2 entities in total)
Functional Keywordsimportin family, transport protein, protein transport-rna binding protein complex, protein transport/rna binding protein
Biological sourceHomo sapiens (Human)
More
Cellular locationCytoplasm: Q92973
Nucleus : P35637
Total number of polymer chains2
Total formula weight114308.53
Authors
Yoshizawa, T.,Fung, H.Y.J.,Chook, Y.M. (deposition date: 2017-11-25, release date: 2018-05-16, Last modification date: 2023-11-22)
Primary citationYoshizawa, T.,Ali, R.,Jiou, J.,Fung, H.Y.J.,Burke, K.A.,Kim, S.J.,Lin, Y.,Peeples, W.B.,Saltzberg, D.,Soniat, M.,Baumhardt, J.M.,Oldenbourg, R.,Sali, A.,Fawzi, N.L.,Rosen, M.K.,Chook, Y.M.
Nuclear Import Receptor Inhibits Phase Separation of FUS through Binding to Multiple Sites.
Cell, 173:693-705.e22, 2018
Cited by
PubMed: 29677513
DOI: 10.1016/j.cell.2018.03.003
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (3.15 Å)
Structure validation

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