5YVH

Crystal structure of Karyopherin beta2 in complex with FUS(371-526)

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0006606	biological_process	protein import into nucleus
A	0006886	biological_process	intracellular protein transport
A	0031267	molecular_function	small GTPase binding
B	0003723	molecular_function	RNA binding
B	0006355	biological_process	regulation of DNA-templated transcription

Functional Information from PROSITE/UniProt

site_id	PS01358
Number of Residues	22
Details	ZF_RANBP2_1 Zinc finger RanBP2-type signature. WkCpnptCenmNfswrneCnqC

Chain	Residue	Details
B	TRP426-CYS447

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	31
Details	ZN_FING: RanBP2-type => ECO:0000255|PROSITE-ProRule:PRU00322

Chain	Residue	Details
B	ARG422-ASP453
A	TRP730

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site_id	SWS_FT_FI2
Number of Residues	13
Details	MOD_RES: Asymmetric dimethylarginine => ECO:0000269|PubMed:12964758

Chain	Residue	Details
B	ARG377
B	ARG487
B	ARG491
B	ARG495
B	ARG498
B	ARG383
B	ARG386
B	ARG388
B	ARG394
B	ARG473
B	ARG476
B	ARG481
B	ARG485

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site_id	SWS_FT_FI3
Number of Residues	1
Details	MOD_RES: Omega-N-methylarginine; alternate => ECO:0000250|UniProtKB:P56959

Chain	Residue	Details
B	ARG407

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site_id	SWS_FT_FI4
Number of Residues	1
Details	MOD_RES: Omega-N-methylarginine; alternate => ECO:0007744|PubMed:24129315

Chain	Residue	Details
B	ARG503

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