5YVH
Crystal structure of Karyopherin beta2 in complex with FUS(371-526)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Transportin-1 | polymer | 868 | 98325.4 | 1 | UniProt (Q92973) Pfam (PF03810) Pfam (PF02985) Pfam (PF13513) In PDB | Homo sapiens (Human) | Importin beta-2,Karyopherin beta-2,M9 region interaction protein,MIP |
| 2 | B | RNA-binding protein FUS | polymer | 158 | 15983.2 | 1 | UniProt (P35637) Pfam (PF00641) In PDB | Homo sapiens (Human) | 75 kDa DNA-pairing protein,Oncogene FUS,Oncogene TLS,POMp75,Translocated in liposarcoma protein |
Sequence modifications
A: 1 - 360 (UniProt: Q92973)
A: 368 - 890 (UniProt: Q92973)
B: 371 - 526 (UniProt: P35637)
| PDB | External Database | Details |
|---|---|---|
| Gly -1 | - | expression tag |
| Ser 0 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Gly 361 | - | linker |
| Gly 362 | - | linker |
| Ser 363 | - | linker |
| Gly 364 | - | linker |
| Gly 365 | - | linker |
| Ser 366 | - | linker |
| Gly 367 | - | linker |
| PDB | External Database | Details |
|---|---|---|
| Gly 369 | - | expression tag |
| Ser 370 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 114308.5 | |
| All* | Total formula weight | 114308.5 |
