8F7A

Cryo-EM structure of Importin-9 bound to RanGTP

Summary for 8F7A

• Entry DOI: 10.2210/pdb8f7a/pdb
• EMDB information: 28899
• Descriptor: Importin-9, GTP-binding nuclear protein GSP1/CNR1, MAGNESIUM ION, ... (4 entities in total)
• Functional Keywords: nuclear import, importin, rangtp, protein transport
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 2
• Total formula weight: 141435.16

Authors

Bernardes, N.E.,Chook, Y.M. (deposition date: 2022-11-18, release date: 2023-07-26)

• Primary citation: Jiou, J.,Shaffer, J.M.,Bernades, N.E.,Fung, H.Y.J.,Kikumoto Dias, J.,D'Arcy, S.,Chook, Y.M.; Mechanism of RanGTP priming H2A-H2B release from Kap114 in an atypical RanGTP•Kap114•H2A-H2B complex.; Proc.Natl.Acad.Sci.USA, 120:e2301199120-e2301199120, 2023; PubMed: 37450495; DOI: 10.1073/pnas.2301199120

Experimental method

ELECTRON MICROSCOPY (3.78 Å)