8F7A

Cryo-EM structure of Importin-9 bound to RanGTP

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005515	molecular_function	protein binding
A	0005634	cellular_component	nucleus
A	0005635	cellular_component	nuclear envelope
A	0005654	cellular_component	nucleoplasm
A	0005737	cellular_component	cytoplasm
A	0005829	cellular_component	cytosol
A	0006606	biological_process	protein import into nucleus
A	0006886	biological_process	intracellular protein transport
A	0015031	biological_process	protein transport
A	0016020	cellular_component	membrane
A	0031144	biological_process	proteasome localization
A	0031267	molecular_function	small GTPase binding
A	0042393	molecular_function	histone binding
A	0061608	molecular_function	nuclear import signal receptor activity
A	0140713	molecular_function	histone chaperone activity
B	0000054	biological_process	ribosomal subunit export from nucleus
B	0000166	molecular_function	nucleotide binding
B	0000467	biological_process	exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
B	0003924	molecular_function	GTPase activity
B	0005515	molecular_function	protein binding
B	0005525	molecular_function	GTP binding
B	0005634	cellular_component	nucleus
B	0005737	cellular_component	cytoplasm
B	0005829	cellular_component	cytosol
B	0006334	biological_process	nucleosome assembly
B	0006606	biological_process	protein import into nucleus
B	0006913	biological_process	nucleocytoplasmic transport
B	0006997	biological_process	nucleus organization
B	0015031	biological_process	protein transport
B	0016973	biological_process	poly(A)+ mRNA export from nucleus
B	0046822	biological_process	regulation of nucleocytoplasmic transport
B	1901987	biological_process	regulation of cell cycle phase transition

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	76
Details	Domain: {"description":"Importin N-terminal","evidences":[{"source":"PROSITE-ProRule","id":"PRU00115","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	8
Details	Region: {"description":"Switch-I","evidences":[{"source":"PROSITE-ProRule","id":"PRU00752","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	16
Details	Region: {"description":"Switch-II","evidences":[{"source":"PROSITE-ProRule","id":"PRU00752","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	13
Details	Binding site: {"evidences":[{"source":"UniProtKB","id":"P62825","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

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