PDB: 435 件ウェブページステータス検索Chemie searchBIRD

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4IUZ	High resolution crystal structure of racemic ester insulin 分子名称: DI(HYDROXYETHYL)ETHER, GLYCEROL, Insulin A chain, ... 著者 Avital-Shmilovici, M, Mandal, K, Gates, Z.P, Phillips, N, Weiss, M.A, Kent, S.B.H. 登録日 2013-01-22 公開日 2013-02-13 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Fully Convergent Chemical Synthesis of Ester Insulin: Determination of the High Resolution X-ray Structure by Racemic Protein Crystallography. J.Am.Chem.Soc., 135, 2013
4IYF	Insulin glargine crystal structure 2 分子名称: Insulin A chain, Insulin B chain 著者 Barba de la Rosa, A.P, Lara-Gonzalez, S, Montero-Moran, G.M, Escobedo-Moratilla, A. 登録日 2013-01-28 公開日 2014-02-12 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Physicochemical and structural analysis of a biosimilar insulin glargine formulation and its reference to be published
3KR3	Crystal structure of IGF-II antibody complex 分子名称: 1,2-ETHANEDIOL, Insulin-like growth factor II, antibody-Fab (heavy chain), ... 著者 Peat, T.S, Newman, J, Adams, T.E. 登録日 2009-11-17 公開日 2010-06-16 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 A human monoclonal antibody against insulin-like growth factor-II blocks the growth of human hepatocellular carcinoma cell lines in vitro and in vivo. Mol.Cancer Ther., 9, 2010
3KQ6	Enhancing the Therapeutic Properties of a Protein by a Designed Zinc-Binding Site, Structural principles of a novel long-acting insulin analog 分子名称: CHLORIDE ION, Insulin A chain, Insulin B chain, ... 著者 Wan, Z.L, Hu, S.Q, Whittaker, L, Phillips, N.B, Whittake, J, Ismail-Beigi, F, Weiss, M.A. 登録日 2009-11-17 公開日 2010-02-23 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Supramolecular protein engineering: design of zinc-stapled insulin hexamers as a long acting depot. J.Biol.Chem., 285, 2010
3LRI	Solution structure and backbone dynamics of long-[Arg(3)]insulin-like growth factor-I 分子名称: PROTEIN (INSULIN-LIKE GROWTH FACTOR I) 著者 Laajoki, L.G, Francis, G.L, Wallace, J.C, Carver, J.A, Keniry, M.A. 登録日 1999-04-13 公開日 2000-05-23 最終更新日 2023-12-27 実験手法 SOLUTION NMR 主引用文献 Solution structure and backbone dynamics of long-[Arg(3)]insulin-like growth factor-I J.Biol.Chem., 275, 2000
3MTH	X-RAY CRYSTALLOGRAPHIC STUDIES ON HEXAMERIC INSULINS IN THE PRESENCE OF HELIX-STABILIZING AGENTS, THIOCYANATE, METHYLPARABEN AND PHENOL 分子名称: 4-HYDROXY-BENZOIC ACID METHYL ESTER, CHLORIDE ION, METHYLPARABEN INSULIN, ... 著者 Whittingham, J.L, Dodson, E.J, Moody, P.C.E, Dodson, G.G. 登録日 1995-09-13 公開日 1996-01-29 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 X-ray crystallographic studies on hexameric insulins in the presence of helix-stabilizing agents, thiocyanate, methylparaben, and phenol. Biochemistry, 34, 1995
4M4J	Radiation damage study of Cu T6-insulin - 0.30 MGy 分子名称: COPPER (II) ION, Insulin 著者 Frankaer, C.G, Harris, P, Stahl, K. 登録日 2013-08-07 公開日 2014-01-15 最終更新日 2018-03-07 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Towards accurate structural characterization of metal centres in protein crystals: the structures of Ni and Cu T6 bovine insulin derivatives. Acta Crystallogr.,Sect.D, 70, 2014
2A3G	The structure of T6 bovine insulin 分子名称: Insulin, ZINC ION 著者 Smith, G.D, Pangborn, W.A, Blessing, R.H. 登録日 2005-06-24 公開日 2005-10-25 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (2.25 Å) 主引用文献 The structure of T6 bovine insulin. Acta Crystallogr.,Sect.D, 61, 2005
2AIY	R6 HUMAN INSULIN HEXAMER (SYMMETRIC), NMR, 20 STRUCTURES 分子名称: PHENOL, PROTEIN (INSULIN) 著者 O'Donoghue, S.I, Chang, X, Abseher, R, Nilges, M, Led, J.J. 登録日 1998-12-28 公開日 2000-02-28 最終更新日 2023-12-27 実験手法 SOLUTION NMR 主引用文献 Unraveling the symmetry ambiguity in a hexamer: calculation of the R6 human insulin structure. J.Biomol.NMR, 16, 2000
2BN3	Insulin before a high dose x-ray burn 分子名称: INSULIN 著者 Nanao, M.H, Ravelli, R.B. 登録日 2005-03-18 公開日 2005-09-07 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 Improving Radiation-Damage Substructures for Rip. Acta Crystallogr.,Sect.D, 61, 2005
2BN1	Insulin after a high dose x-ray burn 分子名称: INSULIN A CHAIN, INSULIN B CHAIN 著者 Nanao, M.H, Ravelli, R.B. 登録日 2005-03-18 公開日 2005-09-07 最終更新日 2013-04-03 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 Improving Radiation-Damage Substructures for Rip. Acta Crystallogr.,Sect.D, 61, 2005
2C8R	insuline(60sec) and UV laser excited fluorescence 分子名称: INSULIN A CHAIN, INSULIN B CHAIN 著者 Vernede, X, Lavault, B, Ohana, J, Nurizzo, D, Joly, J, Jacquamet, L, Felisaz, F, Cipriani, F, Bourgeois, D. 登録日 2005-12-06 公開日 2006-03-08 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Uv Laser-Excited Fluorescence as a Tool for the Visualization of Protein Crystals Mounted in Loops. Acta Crystallogr.,Sect.D, 62, 2006
2C8Q	insuline(1sec) and UV laser excited fluorescence 分子名称: INSULIN A CHAIN, INSULIN B CHAIN 著者 Vernede, X, Lavault, B, Ohana, J, Nurizzo, D, Joly, J, Jacquamet, L, Felisaz, F, Cipriani, F, Bourgeois, D. 登録日 2005-12-06 公開日 2006-03-08 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Uv Laser-Excited Fluorescence as a Tool for the Visualization of Protein Crystals Mounted in Loops. Acta Crystallogr.,Sect.D, 62, 2006
2EFA	Neutron crystal structure of cubic insulin at pD6.6 分子名称: Insulin 著者 Ishikawa, T, Tanaka, I, Niimura, N. 登録日 2007-02-22 公開日 2008-01-22 最終更新日 2023-10-25 実験手法 NEUTRON DIFFRACTION (2.7 Å) 主引用文献 A neutron crystallographic analysis of a cubic porcine insulin at pD 6.6 Chem.Phys., 345, 2008
2G4M	Insulin collected at 2.0 A wavelength 分子名称: Insulin A chain, Insulin B chain 著者 Mueller-Dieckmann, C, Weiss, M.S. 登録日 2006-02-22 公開日 2007-02-20 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 On the routine use of soft X-rays in macromolecular crystallography. Part IV. Efficient determination of anomalous substructures in biomacromolecules using longer X-ray wavelengths. Acta Crystallogr.,Sect.D, 63, 2007
5T7R	A6-A11 trans-dicarba human insulin 分子名称: Insulin A chain, Insulin B chain 著者 Menting, J.G, Lawrence, M.C, Robinson, A.J, Forbes, B.E. 登録日 2016-09-05 公開日 2017-12-06 最終更新日 2019-06-19 実験手法 X-RAY DIFFRACTION (1.55 Å) 主引用文献 Insulin in motion: The A6-A11 disulfide bond allosterically modulates structural transitions required for insulin activity. Sci Rep, 7, 2017
5UDP	High resolution x-ray crystal structure of synthetic insulin lispro 分子名称: CHLORIDE ION, Insulin Lispro A chain, Insulin Lispro B chain, ... 著者 Mandal, K, Dhayalan, B, Kent, S.B.H. 登録日 2016-12-28 公開日 2017-01-11 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.348 Å) 主引用文献 Scope and Limitations of Fmoc Chemistry SPPS-Based Approaches to the Total Synthesis of Insulin Lispro via Ester Insulin. Chemistry, 23, 2017
5USP	Insulin with proline analog Pip at position B28 in the T2 state 分子名称: Insulin Chain A, Insulin Chain B, SODIUM ION 著者 Lieblich, S.A, Fang, K.Y, Tirrell, D.A. 登録日 2017-02-13 公開日 2018-02-21 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (1.174 Å) 主引用文献 Insulin with proline analog Pip at position B28 in the T2 state To Be Published
5UU4	Insulin with proline analog ThioP at position B28 in the R6 state 分子名称: CHLORIDE ION, Insulin A Chain, Insulin B Chain, ... 著者 Lieblich, S.A, Fang, K.Y, Tirrell, D.A. 登録日 2017-02-16 公開日 2018-02-21 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.973 Å) 主引用文献 Insulin with proline analog ThioP at position B28 in the R6 state To Be Published
5USS	Insulin with proline analog PiP at position B28 in the R6 state 分子名称: CHLORIDE ION, Insulin Chain A, Insulin Chain B, ... 著者 Lieblich, S.A, Fang, K.Y, Tirrell, D.A. 登録日 2017-02-13 公開日 2018-02-21 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2.061 Å) 主引用文献 Insulin with proline analog PiP at position B28 in the R6 state To Be Published
5UU2	Insulin with proline analog ThioP at position B28 in the T2 state 分子名称: Insulin Chain A, Insulin Chain B 著者 Lieblich, S.A, Fang, K.Y, Tirrell, D.A. 登録日 2017-02-15 公開日 2018-02-21 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.223 Å) 主引用文献 Insulin with proline analog ThioP at position B28 in the T2 state To Be Published
5USV	Insulin with proline analog AzeP at position B28 in the T2 state 分子名称: Insulin Chain A, Insulin Chain B, SODIUM ION 著者 Lieblich, S.A, Fang, K.Y, Tirrell, D.A. 登録日 2017-02-14 公開日 2018-02-21 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (1.3 Å) 主引用文献 Insulin with proline analog AzeP at position B28 in the T2 state To Be Published
5UOZ	Insulin with proline analog FyP at position B28 in the T2 state 分子名称: Insulin Chain A, Insulin Chain B 著者 Lieblich, S.A, Fang, K.Y, Tirrell, D.A. 登録日 2017-02-01 公開日 2018-02-07 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (1.17463875 Å) 主引用文献 Insulin with proline analog FyP at position B28 in the T2 state To Be Published
5URU	Insulin with proline analog DhP at position B28 in the R6 state 分子名称: CHLORIDE ION, Insulin Chain A, Insulin Chain B, ... 著者 Lieblich, S.A, Fang, K.Y, Tirrell, D.A. 登録日 2017-02-13 公開日 2018-02-21 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2.41 Å) 主引用文献 Insulin with proline analog DhP at position B28 in the R6 state To Be Published
5UQA	Insulin with proline analog FzP at position B28 in the R6 state 分子名称: ACETONE, CHLORIDE ION, GLYCEROL, ... 著者 Lieblich, S.A, Fang, K.Y, Tirrell, D.A. 登録日 2017-02-07 公開日 2018-02-21 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (1.31000245 Å) 主引用文献 Insulin with proline analog FzP at position B28 in the R6 state To Be Published

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