6RVA

STRUCTURE OF [ASP58]-IGF-I ANALOGUE

Summary for 6RVA

• Entry DOI: 10.2210/pdb6rva/pdb
• NMR Information: BMRB: 34408
• Descriptor: Insulin-like growth factor I (1 entity in total)
• Functional Keywords: igf-i analogue, hormone
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 1
• Total formula weight: 7706.78

Authors

Jiracek, J.,Zakova, L.,Socha, O. (deposition date: 2019-05-31, release date: 2019-10-02, Last modification date: 2023-06-14)

• Primary citation: Machackova, K.,Mlcochova, K.,Potalitsyn, P.,Hankova, K.,Socha, O.,Budesinsky, M.,Muzdalo, A.,Lepsik, M.,Cernekova, M.,Radosavljevic, J.,Fabry, M.,Mitrova, K.,Chrudinova, M.,Lin, J.,Yurenko, Y.,Hobza, P.,Selicharova, I.,Zakova, L.,Jiracek, J.; Mutations at hypothetical binding site 2 in insulin and insulin-like growth factors 1 and 2 result in receptor- and hormone-specific responses.; J.Biol.Chem., 294:17371-17382, 2019; PubMed: 31558604; DOI: 10.1074/jbc.RA119.010072

Experimental method

SOLUTION NMR