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9J9H
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High-resolution cryo-EM structure of the Plasmodium falciparum 80S ribosome bound to RACK1 and E-tRNA
分子名称: 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S10, ...
著者Yan, X.F, Gao, Y.G.
登録日2024-08-22
公開日2025-06-04
最終更新日2025-06-18
実験手法ELECTRON MICROSCOPY (2.45 Å)
主引用文献Antimalarial drug artemisinin stabilizes PfRACK1 binding to the ribosome.
Structure, 2025
4TYQ
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BU of 4tyq by Molmil
Crystal structure of an adenylate kinase mutant--AKm2
分子名称: Adenylate kinase, BIS(ADENOSINE)-5'-PENTAPHOSPHATE, CALCIUM ION, ...
著者Moon, S, Bae, E.
登録日2014-07-09
公開日2014-11-26
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Crystal structures of thermally stable adenylate kinase mutants designed by local structural entropy optimization and structure-guided mutagenesis
J KOREAN SOC APPL BIOL CHEM, 57, 2014
5XXB
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BU of 5xxb by Molmil
Large subunit of Toxoplasma gondii ribosome
分子名称: 25S RNA, 5.8S RNA, 5S RNA, ...
著者Li, Z, Guo, Q, Zheng, L, Ji, Y, Xie, Y, Lai, D, Lun, Z, Suo, X, Gao, N.
登録日2017-07-03
公開日2017-08-30
最終更新日2024-10-16
実験手法ELECTRON MICROSCOPY (3.17 Å)
主引用文献Cryo-EM structures of the 80S ribosomes from human parasites Trichomonas vaginalis and Toxoplasma gondii
Cell Res., 27, 2017
4U3M
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BU of 4u3m by Molmil
Crystal structure of Anisomycin bound to the yeast 80S ribosome
分子名称: 18S rRNA, 25s rRNA, 40S ribosomal protein S0-A, ...
著者Garreau de Loubresse, N, Prokhorova, I, Yusupova, G, Yusupov, M.
登録日2014-07-22
公開日2014-10-22
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structural basis for the inhibition of the eukaryotic ribosome.
Nature, 513, 2014
4U52
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BU of 4u52 by Molmil
Crystal structure of Nagilactone C bound to the yeast 80S ribosome
分子名称: 18S ribosomal RNA, 25S ribosomal RNA, 40S ribosomal protein S0-A, ...
著者Garreau de Loubresse, N, Prokhorova, I, Yusupova, G, Yusupov, M.
登録日2014-07-24
公開日2014-10-22
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structural basis for the inhibition of the eukaryotic ribosome.
Nature, 513, 2014
9MHT
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BU of 9mht by Molmil
CYTOSINE-SPECIFIC METHYLTRANSFERASE HHAI/DNA COMPLEX
分子名称: 5'-D(P*CP*CP*AP*TP*GP*CP*GP*CP*TP*GP*AP*C)-3', 5'-D(P*GP*TP*CP*AP*GP*(3DR)P*GP*CP*AP*TP*GP*G)-3', CYTOSINE-SPECIFIC METHYLTRANSFERASE HHAI, ...
著者O'Gara, M, Horton, J.R, Roberts, R.J, Cheng, X.
登録日1998-08-07
公開日1998-12-01
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.39 Å)
主引用文献Structures of HhaI methyltransferase complexed with substrates containing mismatches at the target base.
Nat.Struct.Biol., 5, 1998
5X6J
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BU of 5x6j by Molmil
Crystal structure of B. globisporus adenylate kinase variant
分子名称: Adenylate kinase, BIS(ADENOSINE)-5'-PENTAPHOSPHATE, ZINC ION
著者Moon, S, Bae, E.
登録日2017-02-22
公開日2018-02-28
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structural and mutational analyses of psychrophilic and mesophilic adenylate kinases highlight the role of hydrophobic interactions in protein thermal stability.
Struct Dyn., 6, 2019
4V7E
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BU of 4v7e by Molmil
Model of the small subunit RNA based on a 5.5 A cryo-EM map of Triticum aestivum translating 80S ribosome
分子名称: 18S ribosomal RNA, 40S ribosomal protein S10, 40S ribosomal protein S10E, ...
著者Barrio-Garcia, C, Armache, J.-P, Jarasch, A, Anger, A.M, Villa, E, Becker, T, Bhushan, S, Jossinet, F, Habeck, M, Dindar, G, Franckenberg, S, Marquez, V, Mielke, T, Thomm, M, Berninghausen, O, Beatrix, B, Soeding, J, Westhof, E, Wilson, D.N, Beckmann, R.
登録日2013-11-22
公開日2014-07-09
最終更新日2024-11-20
実験手法ELECTRON MICROSCOPY (5.5 Å)
主引用文献Structures of the Sec61 complex engaged in nascent peptide translocation or membrane insertion.
Nature, 506, 2014
6FAI
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BU of 6fai by Molmil
Structure of a eukaryotic cytoplasmic pre-40S ribosomal subunit
分子名称: 20S ribosomal RNA, 40S ribosomal protein S0-A, 40S ribosomal protein S1-A, ...
著者Scaiola, A, Pena, C, Weisser, M, Boehringer, D, Leibundgut, M, Klingauf-Nerurkar, P, Gerhardy, S, Panse, V.G, Ban, N.
登録日2017-12-15
公開日2018-02-28
最終更新日2024-05-15
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Structure of a eukaryotic cytoplasmic pre-40S ribosomal subunit.
EMBO J., 37, 2018
5XXU
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BU of 5xxu by Molmil
Small subunit of Toxoplasma gondii ribosome
分子名称: 18S RNA, Ribosomal protein eL41, Ribosomal protein eS1, ...
著者LI, Z, Guo, Q, Zheng, L, Ji, Y, Xie, Y, Lai, D, Lun, Z, Suo, X, Gao, N.
登録日2017-07-05
公開日2017-08-30
最終更新日2024-10-09
実験手法ELECTRON MICROSCOPY (3.35 Å)
主引用文献Cryo-EM structures of the 80S ribosomes from human parasites Trichomonas vaginalis and Toxoplasma gondii
Cell Res., 27, 2017
2UYC
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BU of 2uyc by Molmil
HhaI DNA methyltransferase R163N mutant complex with 13mer GCGC-GMGC oligonucleotide and SAH
分子名称: 5'-D(*GP*TP*CP*AP*GP*CP*GP*CP*AP*TP *CP*C)-3', 5'-D(*TP*GP*GP*AP*TP*GP*5CMP*GP*CP*TP *GP*AP*C)-3', GLYCEROL, ...
著者Daujotyte, D, Grazulis, S.
登録日2007-04-03
公開日2008-05-27
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献HhaI DNA Methyltransferase R163N Mutant Complex with 13mer Gcgc-Gmgc Oligonucleotide and Sah
To be Published
2UZ4
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BU of 2uz4 by Molmil
HhaI DNA methyltransferase R165N mutant complex with 13mer GCGC-GMGC oligonucleotide and SAH
分子名称: 5'-D(*GP*TP*CP*AP*GP*CP*GP*CP*AP*TP *CP*C)-3', 5'-D(*TP*GP*GP*AP*TP*GP*5CMP*GP*CP*TP*GP *AP*C)-3', GLYCEROL, ...
著者Daujotyte, D, Leinartaite, L, Grazulis, S.
登録日2007-04-25
公開日2008-06-03
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献DNA Methyltransferase R165N Mutant
To be Published
3JBN
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BU of 3jbn by Molmil
Cryo-electron microscopy reconstruction of the Plasmodium falciparum 80S ribosome bound to P-tRNA
分子名称: 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein eS1, ...
著者Sun, M, Li, W, Blomqvist, K, Das, S, Hashem, Y, Dvorin, J.D, Frank, J.
登録日2015-09-16
公開日2015-10-14
最終更新日2024-02-21
実験手法ELECTRON MICROSCOPY (4.7 Å)
主引用文献Dynamical features of the Plasmodium falciparum ribosome during translation.
Nucleic Acids Res., 43, 2015
6TH6
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BU of 6th6 by Molmil
Cryo-EM Structure of T. kodakarensis 70S ribosome
分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
著者Matzov, D, Sas-Chen, A, Thomas, J.M, Santangelo, T, Meier, J.L, Schwartz, S, Shalev-Benami, M.
登録日2019-11-18
公開日2020-07-29
最終更新日2024-04-24
実験手法ELECTRON MICROSCOPY (2.55 Å)
主引用文献Dynamic RNA acetylation revealed by quantitative cross-evolutionary mapping.
Nature, 583, 2020
3J6X
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S. cerevisiae 80S ribosome bound with Taura syndrome virus (TSV) IRES, 5 degree rotation (Class II)
分子名称: 18S ribosomal RNA, 25S ribosomal RNA, 40S ribosomal protein S0, ...
著者Koh, C.S, Brilot, A.F, Grigorieff, N, Korostelev, A.A.
登録日2014-04-16
公開日2014-06-11
最終更新日2024-02-21
実験手法ELECTRON MICROSCOPY (6.1 Å)
主引用文献Taura syndrome virus IRES initiates translation by binding its tRNA-mRNA-like structural element in the ribosomal decoding center.
Proc.Natl.Acad.Sci.USA, 111, 2014
3J80
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BU of 3j80 by Molmil
CryoEM structure of 40S-eIF1-eIF1A preinitiation complex
分子名称: 18S rRNA, MAGNESIUM ION, RACK1, ...
著者Hussain, T, Llacer, J.L, Fernandez, I.S, Savva, C.G, Ramakrishnan, V.
登録日2014-08-28
公開日2014-11-05
最終更新日2024-02-21
実験手法ELECTRON MICROSCOPY (3.75 Å)
主引用文献Structural changes enable start codon recognition by the eukaryotic translation initiation complex.
Cell(Cambridge,Mass.), 159, 2014
3JAP
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BU of 3jap by Molmil
Structure of a partial yeast 48S preinitiation complex in closed conformation
分子名称: 18S rRNA, MAGNESIUM ION, METHIONINE, ...
著者Llacer, J.L, Hussain, T, Ramakrishnan, V.
登録日2015-06-18
公開日2015-08-12
最終更新日2024-02-21
実験手法ELECTRON MICROSCOPY (4.9 Å)
主引用文献Conformational Differences between Open and Closed States of the Eukaryotic Translation Initiation Complex.
Mol.Cell, 59, 2015
6TB3
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BU of 6tb3 by Molmil
yeast 80S ribosome in complex with the Not5 subunit of the CCR4-NOT complex
分子名称: 25S rRNA, 40S ribosomal protein S0-A, 40S ribosomal protein S1-A, ...
著者Buschauer, R, Cheng, J, Berninghausen, O, Tesina, P, Becker, T, Beckmann, R.
登録日2019-10-31
公開日2020-04-22
最終更新日2024-05-22
実験手法ELECTRON MICROSCOPY (2.8 Å)
主引用文献The Ccr4-Not complex monitors the translating ribosome for codon optimality.
Science, 368, 2020
3J78
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BU of 3j78 by Molmil
Structures of yeast 80S ribosome-tRNA complexes in the rotated and non-rotated conformations (Class I - non-rotated ribosome with 2 tRNAs)
分子名称: 18S ribosomal RNA, 25S ribosomal RNA, 40S ribosomal protein S0, ...
著者Svidritskiy, E, Brilot, A.F, Koh, C.S, Grigorieff, N, Korostelev, A.A.
登録日2014-05-29
公開日2014-08-06
最終更新日2024-02-21
実験手法ELECTRON MICROSCOPY (6.3 Å)
主引用文献Structures of Yeast 80S Ribosome-tRNA Complexes in the Rotated and Nonrotated Conformations.
Structure, 22, 2014
3JAI
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BU of 3jai by Molmil
Structure of a mammalian ribosomal termination complex with ABCE1, eRF1(AAQ), and the UGA stop codon
分子名称: 18S ribosomal RNA, 28S ribosomal RNA, 5.8S ribosomal RNA, ...
著者Brown, A, Shao, S, Murray, J, Hegde, R.S, Ramakrishnan, V.
登録日2015-06-10
公開日2015-08-12
最終更新日2024-11-27
実験手法ELECTRON MICROSCOPY (3.65 Å)
主引用文献Structural basis for stop codon recognition in eukaryotes.
Nature, 524, 2015
3JAJ
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BU of 3jaj by Molmil
Structure of the engaged state of the mammalian SRP-ribosome complex
分子名称: 18S ribosomal RNA, 28S ribosomal RNA, 5.8S ribosomal RNA, ...
著者Voorhees, R.M, Hegde, R.S.
登録日2015-06-16
公開日2015-08-05
最終更新日2024-10-30
実験手法ELECTRON MICROSCOPY (3.75 Å)
主引用文献Structures of the scanning and engaged states of the mammalian SRP-ribosome complex.
Elife, 4, 2015
5JUS
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BU of 5jus by Molmil
Saccharomyces cerevisiae 80S ribosome bound with elongation factor eEF2-GDP-sordarin and Taura Syndrome Virus IRES, Structure III (mid-rotated 40S subunit)
分子名称: 18S ribosomal RNA, 25S ribosomal RNA, 5.8S ribosomal RNA, ...
著者Abeyrathne, P, Koh, C.S, Grant, T, Grigorieff, N, Korostelev, A.A.
登録日2016-05-10
公開日2016-10-05
最終更新日2023-04-05
実験手法ELECTRON MICROSCOPY (4.2 Å)
主引用文献Ensemble cryo-EM uncovers inchworm-like translocation of a viral IRES through the ribosome.
Elife, 5, 2016
5K4L
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Crystal structure of KDM5A in complex with a naphthyridone inhibitor
分子名称: Lysine-specific demethylase 5A, NICKEL (II) ION, Unknown Peptide, ...
著者Kiefer, J.R, Vinogradova, M.V.
登録日2016-05-20
公開日2016-08-10
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (3.179 Å)
主引用文献Design and evaluation of 1,7-naphthyridones as novel KDM5 inhibitors.
Bioorg.Med.Chem.Lett., 26, 2016
5K0Y
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m48S late-stage initiation complex, purified from rabbit reticulocytes lysates, displaying eIF2 ternary complex and eIF3 i and g subunits relocated to the intersubunit face
分子名称: 18S ribosomal RNA, 40S ribosomal protein S12, 40S ribosomal protein S21, ...
著者Simonetti, A, Brito Querido, J, Myasnikov, A.G, Mancera-Martinez, E, Renaud, A, Kuhn, L, Hashem, Y.
登録日2016-05-17
公開日2016-07-13
最終更新日2025-05-07
実験手法ELECTRON MICROSCOPY (5.8 Å)
主引用文献eIF3 Peripheral Subunits Rearrangement after mRNA Binding and Start-Codon Recognition.
Mol.Cell, 63, 2016
6T83
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Structure of yeast disome (di-ribosome) stalled on poly(A) tract.
分子名称: 18S rRNA, 25S rRNA, 40S ribosomal protein S0-A, ...
著者Tesina, P, Buschauer, R, Cheng, J, Berninghausen, O, Becker, R, Beckmann, R.
登録日2019-10-24
公開日2019-12-25
最終更新日2024-11-06
実験手法ELECTRON MICROSCOPY (4 Å)
主引用文献Molecular mechanism of translational stalling by inhibitory codon combinations and poly(A) tracts.
Embo J., 39, 2020

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