PDB: 45953 件ウェブページステータス検索Chemie searchBIRD

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4N95	E. coli sliding clamp in complex with 5-chloroindoline-2,3-dione 分子名称: 5-chloro-1H-indole-2,3-dione, CALCIUM ION, CHLORIDE ION, ... 著者 Yin, Z, Oakley, A.J. 登録日 2013-10-19 公開日 2013-11-06 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Discovery of lead compounds targeting the bacterial sliding clamp using a fragment-based approach. J.Med.Chem., 57, 2014
1UOL	Crystal structure of the human p53 core domain mutant M133L/V203A/N239Y/N268D at 1.9 A resolution. 分子名称: CELLULAR TUMOR ANTIGEN P53, ZINC ION 著者 Joerger, A.C, Allen, M.D, Fersht, A.R. 登録日 2003-09-19 公開日 2003-10-16 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Crystal Structure of a Superstable Mutant of Human P53 Core Domain. Insights Into the Mechanism of Rescuing Oncogenic Mutations J.Biol.Chem., 279, 2004
2L4A	NMR structure of the DNA-binding domain of E.coli Lrp 分子名称: Leucine responsive regulatory protein 著者 Kawamura, T, Zhou, H, Dahlquist, F.W. 登録日 2010-10-01 公開日 2011-03-09 最終更新日 2024-05-01 実験手法 SOLUTION NMR 主引用文献 The design involved in PapI and Lrp regulation of the pap operon. J.Mol.Biol., 409, 2011
7V97	Arsenic-bound p53 DNA-binding domain mutant V272M 分子名称: ARSENIC, Cellular tumor antigen p53, ZINC ION 著者 Lu, M, Xing, Y.F, Wang, Z.Y, Ni, Y, Song, H.X. 登録日 2021-08-24 公開日 2022-08-31 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.02 Å) 主引用文献 Diverse rescue potencies of p53 mutations to ATO are predetermined by intrinsic mutational properties. Sci Transl Med, 15, 2023
5N9F	Crystal Structure of Drosophila DHX36 helicase in complex with ssDNA CpG_A 分子名称: CG9323, isoform A, CHLORIDE ION, ... 著者 Chen, W.-F, Rety, S, Hai-Lei Guo, H.-L, Wu, W.-Q, Liu, N.-N, Liu, Q.-W, Dai, Y.-X, Xi, X.-G. 登録日 2017-02-24 公開日 2018-03-21 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.969 Å) 主引用文献 Structural and mechanistic insights into DHX36-mediated innate immunity and G-quadruplex unfolding To Be Published
7XRC	Crystal Structure of the dimeric Brn2 (Pou3f2) POU domain bound to palindromic MORE DNA 分子名称: More palindromic Oct factor Recognition Element (MORE), POU domain protein 著者 Tan, D.S.Y, Jauch, R. 登録日 2022-05-10 公開日 2022-06-15 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.89 Å) 主引用文献 The homeodomain of Oct4 is a dimeric binder of methylated CpG elements. Nucleic Acids Res., 51, 2023
1GDT	CRYSTAL STRUCTURE OF A SITE-SPECIFIC RECOMBINASE, GAMMA-DELTA RESOLVASE COMPLEXED WITH A 34 BP CLEAVAGE SITE 分子名称: PROTEIN (GAMMA DELTA RESOLVASE), SITE I OF RES DNA 著者 Yang, W, Steitz, T.A. 登録日 1995-04-11 公開日 1996-04-03 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Crystal structure of the site-specific recombinase gamma delta resolvase complexed with a 34 bp cleavage site. Cell(Cambridge,Mass.), 82, 1995
1H38	Structure of a T7 RNA polymerase elongation complex at 2.9A resolution 分子名称: 5'-D(*GP*GP*GP*AP*AP*TP*CP*GP*AP*CP *AP*TP*CP*GP*CP*CP*GP*C)-3', 5'-D(*GP*TP*CP*GP*AP*TP*TP*CP*CP*CP)-3', 5'-R(*AP*AP*CP*UP*GP*CP*GP*GP*CP*GP *AP*U)-3', ... 著者 Tahirov, T.H, Temyakov, D, Anikin, M, Patlan, V, McAllister, W.T, Vassylyev, D.G, Yokoyama, S. 登録日 2002-08-24 公開日 2002-11-20 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Structure of a T7 RNA Polymerase Elongation Complex at 2.9 A Resolution Nature, 420, 2002
5GKS	Crystal structure of SLE patient-derived anti-DNA antibody 分子名称: IgG2, Fab (heavy chain), PHOSPHATE ION, ... 著者 Arimori, T, Sakakibara, S, Kikutani, H, Takagi, J. 登録日 2016-07-05 公開日 2017-07-05 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.05 Å) 主引用文献 Clonal evolution and antigen recognition of anti-nuclear antibodies in acute systemic lupus erythematosus Sci Rep, 7, 2017
4I6R	High Resolution Crystal Structure of the Wild-Type Restriction-Modification Controller Protein C.Esp1396I (Triclinic form) 分子名称: GLYCEROL, Regulatory protein, SULFATE ION 著者 Martin, R.N.A, McGeehan, J.E, Kneale, G.G. 登録日 2012-11-30 公開日 2013-11-13 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.38 Å) 主引用文献 Structural and Mutagenic Analysis of the RM Controller Protein C.Esp1396I. Plos One, 9, 2014
8JKL	IRF4 DNA-binding domain bound to an DNA containing GATA motif 分子名称: GATA-Forward, GATA-Reverse, Interferon regulatory factor 4 著者 Wang, G, Feng, X, Ding, J. 登録日 2023-06-01 公開日 2023-09-20 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2.94 Å) 主引用文献 Molecular basis for the functional roles of the multimorphic T95R mutation of IRF4 causing human autosomal dominant combined immunodeficiency. Structure, 31, 2023
8JKQ	T95R mutant IRF4 DNA-binding domain bound to an DNA containing GACA motif 分子名称: GACA-Forward, GACA-Reverse, Interferon regulatory factor 4 著者 Wang, G, Feng, X, Ding, J. 登録日 2023-06-01 公開日 2023-09-20 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (3.09 Å) 主引用文献 Molecular basis for the functional roles of the multimorphic T95R mutation of IRF4 causing human autosomal dominant combined immunodeficiency. Structure, 31, 2023
4IA8	Crystal Structure of a Y37A mutant of the Restriction-Modification Controller Protein C.Esp1396I 分子名称: Regulatory protein, SULFATE ION 著者 Martin, R.N.A, McGeehan, J.E, Kneale, G.G. 登録日 2012-12-06 公開日 2013-12-11 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Structural and Mutagenic Analysis of the RM Controller Protein C.Esp1396I. Plos One, 9, 2014
8JKN	T95R mutant IRF4 DNA-binding domain bound to an DNA containing GAAA motif 分子名称: GAAA-Forward, GAAA-Reverse, Interferon regulatory factor 4 著者 Wang, G, Feng, X, Ding, J. 登録日 2023-06-01 公開日 2023-09-20 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2.92 Å) 主引用文献 Molecular basis for the functional roles of the multimorphic T95R mutation of IRF4 causing human autosomal dominant combined immunodeficiency. Structure, 31, 2023
8JKO	T95R mutant IRF4 DNA-binding domain bound to an DNA containing GATA motif 分子名称: GATA-Forward, GATA-Reverse, Interferon regulatory factor 4 著者 Wang, G, Feng, X, Ding, J. 登録日 2023-06-01 公開日 2023-09-20 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2.95 Å) 主引用文献 Molecular basis for the functional roles of the multimorphic T95R mutation of IRF4 causing human autosomal dominant combined immunodeficiency. Structure, 31, 2023
1FBU	HEAT SHOCK TRANSCRIPTION FACTOR DNA BINDING DOMAIN 分子名称: HEAT SHOCK FACTOR PROTEIN 著者 Hardy, J.A, Nelson, H.C.M. 登録日 2000-07-16 公開日 2001-01-10 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Proline in alpha-helical kink is required for folding kinetics but not for kinked structure, function, or stability of heat shock transcription factor. Protein Sci., 9, 2000
1FBQ	HEAT SHOCK TRANSCRIPTION FACTOR DNA BINDING DOMAIN CONTAINING THE P237K MUTATION 分子名称: HEAT SHOCK FACTOR PROTEIN 著者 Hardy, J.A, Nelson, H.C.M. 登録日 2000-07-16 公開日 2001-01-17 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Proline in alpha-helical kink is required for folding kinetics but not for kinked structure, function, or stability of heat shock transcription factor. Protein Sci., 9, 2000
8JKS	T95R mutant IRF4 DNA-binding domain bound to an DNA containing GAGA motif 分子名称: GAGA-Forward, GAGA-Reverse, Interferon regulatory factor 4 著者 Wang, G, Feng, X, Ding, J. 登録日 2023-06-01 公開日 2023-09-20 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (3.3 Å) 主引用文献 Molecular basis for the functional roles of the multimorphic T95R mutation of IRF4 causing human autosomal dominant combined immunodeficiency. Structure, 31, 2023
4I6U	Crystal Structure of a Y37F mutant of the Restriction-Modification Controller Protein C.Esp1396I 分子名称: ACETATE ION, DI(HYDROXYETHYL)ETHER, GLYCEROL, ... 著者 Martin, R.N.A, McGeehan, J.E, Kneale, G.G. 登録日 2012-11-30 公開日 2013-11-13 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.97 Å) 主引用文献 Structural and Mutagenic Analysis of the RM Controller Protein C.Esp1396I. Plos One, 9, 2014
4I6T	Crystal Structure of a T36A mutant of the Restriction-Modification Controller Protein C.Esp1396I 分子名称: MALONATE ION, Regulatory protein 著者 Martin, R.N.A, McGeehan, J.E, Kneale, G.G. 登録日 2012-11-30 公開日 2013-11-13 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structural and Mutagenic Analysis of the RM Controller Protein C.Esp1396I. Plos One, 9, 2014
4CSR	High resolution crystal structure of the histone fold dimer (NF-YB)-(NF-YC) 分子名称: GLYCEROL, NUCLEAR TRANSCRIPTION FACTOR Y SUBUNIT BETA, NUCLEAR TRANSCRIPTION FACTOR Y SUBUNIT GAMMA 著者 Gnesutta, N, Cocolo, S, Mantovani, R, Bolognesi, M, Nardini, M. 登録日 2014-03-09 公開日 2015-03-18 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 High Resolution Crystal Structure of the Histone Fold Dimer (NF-Yb)-(NF-Yc) To be Published
1ENH	STRUCTURAL STUDIES OF THE ENGRAILED HOMEODOMAIN 分子名称: ENGRAILED HOMEODOMAIN 著者 Clarke, N.D, Kissinger, C.R, Desjarlais, J, Gilliland, G.L, Pabo, C.O. 登録日 1994-05-20 公開日 1994-08-31 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Structural studies of the engrailed homeodomain. Protein Sci., 3, 1994
7SVU	TnsBctd-TnsC-TniQ complex 分子名称: ADENOSINE-5'-TRIPHOSPHATE, DNA (28-MER), DNA (29-MER), ... 著者 Park, J, Tsai, A.W.T, Kellogg, E.H. 登録日 2021-11-19 公開日 2022-11-23 最終更新日 2024-06-05 実験手法 ELECTRON MICROSCOPY (3.5 Å) 主引用文献 Structures of the holo CRISPR RNA-guided transposon integration complex Nature, 613, 2023
7PT7	Structure of MCM2-7 DH complexed with Cdc7-Dbf4 in the presence of ADP:BeF3, state I 分子名称: ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, Cell division control protein 7, ... 著者 Saleh, A, Noguchi, Y, Aramayo, R, Ivanova, M.E, Speck, C. 登録日 2021-09-26 公開日 2022-06-08 最終更新日 2024-07-17 実験手法 ELECTRON MICROSCOPY (3.8 Å) 主引用文献 The structural basis of Cdc7-Dbf4 kinase dependent targeting and phosphorylation of the MCM2-7 double hexamer. Nat Commun, 13, 2022
7PT6	Structure of MCM2-7 DH complexed with Cdc7-Dbf4 in the presence of ATPgS, state III 分子名称: ADENOSINE-5'-DIPHOSPHATE, Cell division control protein 7, DDK kinase regulatory subunit DBF4, ... 著者 Saleh, A, Noguchi, Y, Aramayo, R, Ivanova, M.E, Speck, C. 登録日 2021-09-26 公開日 2022-06-08 最終更新日 2024-07-17 実験手法 ELECTRON MICROSCOPY (3.2 Å) 主引用文献 The structural basis of Cdc7-Dbf4 kinase dependent targeting and phosphorylation of the MCM2-7 double hexamer. Nat Commun, 13, 2022

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