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4UN8
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BU of 4un8 by Molmil
THE CRYSTAL STRUCTURE OF I-DMOI IN COMPLEX WITH ITS TARGET DNA AT 1H INCUBATION IN 5MM MN (STATE 2)
分子名称: 25MER, HOMING ENDONUCLEASE I-DMOI, MANGANESE (II) ION
著者Molina, R, Stella, S, Redondo, P, Gomez, H, Marcaida, M.J, Orozco, M, Prieto, J, Montoya, G.
登録日2014-05-26
公開日2014-12-17
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Visualizing Phosphodiester-Bond Hydrolysis by an Endonuclease.
Nat.Struct.Mol.Biol., 22, 2015
3LLR
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BU of 3llr by Molmil
Crystal structure of the PWWP domain of Human DNA (cytosine-5-)-methyltransferase 3 alpha
分子名称: 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, DNA (cytosine-5)-methyltransferase 3A, SULFATE ION
著者Qiu, W, Dombrovski, L, Ni, S, Weigelt, J, Boutra, C, Arrowsmith, C.H, Edwards, A.M, Min, J, Wu, H, Structural Genomics Consortium (SGC)
登録日2010-01-29
公開日2010-03-23
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structural and histone binding ability characterizations of human PWWP domains.
Plos One, 6, 2011
3LJA
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BU of 3lja by Molmil
Using Soft X-Rays for a Detailed Picture of Divalent Metal Binding in the Nucleosome
分子名称: 147mer DNA, Histone H2A, Histone H2B 1.1, ...
著者Wu, B, Davey, C.A.
登録日2010-01-26
公開日2010-04-14
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.75 Å)
主引用文献Using soft X-rays for a detailed picture of divalent metal binding in the nucleosome
J.Mol.Biol., 398, 2010
6XRE
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BU of 6xre by Molmil
Structure of the p53/RNA polymerase II assembly
分子名称: Cellular tumor antigen p53, DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11-a, ...
著者Liou, S.-H, Singh, S, Singer, R.H, Coleman, R.A, Liu, W.
登録日2020-07-12
公開日2021-03-24
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (4.6 Å)
主引用文献Structure of the p53/RNA polymerase II assembly.
Commun Biol, 4, 2021
6O9L
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BU of 6o9l by Molmil
Human holo-PIC in the closed state
分子名称: CDK-activating kinase assembly factor MAT1, Cyclin-H, Cyclin-dependent kinase 7, ...
著者Yan, C.L, Dodd, T, He, Y, Tainer, J.A, Tsutakawa, S.E, Ivanov, I.
登録日2019-03-14
公開日2019-05-29
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (7.2 Å)
主引用文献Transcription preinitiation complex structure and dynamics provide insight into genetic diseases.
Nat.Struct.Mol.Biol., 26, 2019
3UMZ
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BU of 3umz by Molmil
Crystal Structure of the human MDC1 FHA Domain
分子名称: Mediator of DNA damage checkpoint protein 1
著者Luo, S, Ye, K.
登録日2011-11-15
公開日2012-01-25
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Structural mechanism of the phosphorylation-dependent dimerization of the MDC1 forkhead-associated domain
Nucleic Acids Res., 40, 2012
2G8I
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BU of 2g8i by Molmil
B. halodurans RNase H catalytic domain D192N mutant in complex with Mn2+ and RNA/DNA hybrid (non-P nick at the active site)
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, 5'-D(*AP*TP*GP*TP*CP*G)-3', 5'-R(*UP*CP*GP*AP*CP*A)-3', ...
著者Nowotny, M, Yang, W.
登録日2006-03-02
公開日2006-04-25
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Stepwise analyses of metal ions in RNase H catalysis from substrate destabilization to product release.
Embo J., 25, 2006
2G8W
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BU of 2g8w by Molmil
B. halodurans RNase H catalytic domain E188A mutant in complex with Ca2+ and RNA/DNA hybrid
分子名称: 5'-D(*AP*TP*GP*TP*CP*G)-3', 5'-R(P*UP*CP*GP*AP*CP*A)-3', CALCIUM ION, ...
著者Nowotny, M, Yang, W.
登録日2006-03-03
公開日2006-04-25
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Stepwise analyses of metal ions in RNase H catalysis from substrate destabilization to product release.
Embo J., 25, 2006
5LB3
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BU of 5lb3 by Molmil
Crystal structure of human RECQL5 helicase in complex with ADP/Mg.
分子名称: ADENOSINE-5'-DIPHOSPHATE, ATP-dependent DNA helicase Q5, MAGNESIUM ION, ...
著者Newman, J.A, Aitkenhead, H, Savitsky, P, Krojer, T, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Gileadi, O, Structural Genomics Consortium (SGC)
登録日2016-06-15
公開日2016-07-06
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Insights into the RecQ helicase mechanism revealed by the structure of the helicase domain of human RECQL5.
Nucleic Acids Res., 45, 2017
2G8V
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BU of 2g8v by Molmil
B. halodurans RNase H catalytic domain E188A mutant in complex with Mg2+ and RNA/DNA hybrid (reaction product)
分子名称: 5'-D(*AP*TP*GP*TP*CP*G)-3', 5'-R(P*UP*CP*GP*AP*CP*A)-3', ETHANOL, ...
著者Nowotny, M, Yang, W.
登録日2006-03-03
公開日2006-04-25
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Stepwise analyses of metal ions in RNase H catalysis from substrate destabilization to product release.
Embo J., 25, 2006
2G8K
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BU of 2g8k by Molmil
B. halodurans RNase H catalytic domain D192N mutant in complex with Ca2+ and RNA/DNA hybrid (non-P nick at the active site)
分子名称: 5'-D(*AP*TP*GP*TP*CP*G)-3', 5'-R(*UP*CP*GP*AP*CP*A)-3', CALCIUM ION, ...
著者Nowotny, M, Yang, W.
登録日2006-03-02
公開日2006-04-25
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Stepwise analyses of metal ions in RNase H catalysis from substrate destabilization to product release.
Embo J., 25, 2006
2G8H
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BU of 2g8h by Molmil
B. halodurans RNase H catalytic domain D192N mutant in complex with Mg2+ and RNA/DNA hybrid (non-P nick at the active site)
分子名称: 5'-D(*AP*TP*GP*TP*CP*G)-3', 5'-R(*UP*CP*GP*AP*CP*A)-3', MAGNESIUM ION, ...
著者Nowotny, M, Yang, W.
登録日2006-03-02
公開日2006-04-25
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Stepwise analyses of metal ions in RNase H catalysis from substrate destabilization to product release.
Embo J., 25, 2006
5LB8
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BU of 5lb8 by Molmil
Crystal structure of human RECQL5 helicase APO form.
分子名称: ATP-dependent DNA helicase Q5, ZINC ION
著者Newman, J.A, Aitkenhead, H, Savitsky, P, Krojer, T, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Gileadi, O, Structural Genomics Consortium (SGC)
登録日2016-06-15
公開日2016-07-06
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (3.4 Å)
主引用文献Insights into the RecQ helicase mechanism revealed by the structure of the helicase domain of human RECQL5.
Nucleic Acids Res., 45, 2017
5LB5
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BU of 5lb5 by Molmil
Crystal structure of human RECQL5 helicase in complex with ADP/Mg (tricilinc form).
分子名称: ADENOSINE-5'-DIPHOSPHATE, ATP-dependent DNA helicase Q5, DIMETHYL SULFOXIDE, ...
著者Newman, J.A, Aitkenhead, H, Savitsky, P, Krojer, T, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Gileadi, O, Structural Genomics Consortium (SGC)
登録日2016-06-15
公開日2016-07-06
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Insights into the RecQ helicase mechanism revealed by the structure of the helicase domain of human RECQL5.
Nucleic Acids Res., 45, 2017
1HKQ
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BU of 1hkq by Molmil
PPS10 plasmid DNA replication initiator protein RepA. Replication inactive, dimeric N-terminal domain.
分子名称: BENZOIC ACID, MERCURY (II) ION, PHOSPHATE ION, ...
著者Giraldo, R, Fernandez-Tornero, C, Evans, P.R, Diaz-Orejas, R, Romero, A.
登録日2003-03-11
公開日2003-05-29
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.75 Å)
主引用文献A Conformational Switch between Transcriptional Repression and Replication Initiation in Repa Dimerization Domain
Nat.Struct.Biol., 10, 2003
2G8F
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BU of 2g8f by Molmil
B. halodurans RNase H catalytic domain E188A mutant in complex with Mg2+ and RNA/DNA hybrid (non-P nick at the active site)
分子名称: 5'-D(*AP*TP*GP*TP*CP*G)-3', 5'-R(*UP*CP*GP*AP*CP*A)-3', CHLORIDE ION, ...
著者Nowotny, M, Yang, W.
登録日2006-03-02
公開日2006-04-25
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Stepwise analyses of metal ions in RNase H catalysis from substrate destabilization to product release.
Embo J., 25, 2006
2G8U
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BU of 2g8u by Molmil
B. halodurans RNase H catalytic domain D132N mutant in complex with Mg2+ and RNA/DNA hybrid (non-P nick at the active site)
分子名称: 5'-D(*AP*TP*GP*TP*CP*G)-3', 5'-R(*UP*CP*GP*AP*CP*A)-3', MAGNESIUM ION, ...
著者Nowotny, M, Yang, W.
登録日2006-03-03
公開日2006-04-25
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Stepwise analyses of metal ions in RNase H catalysis from substrate destabilization to product release.
Embo J., 25, 2006
7OQY
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BU of 7oqy by Molmil
Cryo-EM structure of the cellular negative regulator TFS4 bound to the archaeal RNA polymerase
分子名称: Conserved protein, DNA-directed RNA polymerase subunit A', DNA-directed RNA polymerase subunit A'', ...
著者Pilotto, S, Fouqueau, T, Lukoyanova, N, Sheppard, C, Lucas-Staat, S, Diaz-Santin, L.M, Matelska, D, Prangishvili, D, Cheung, A.C.M, Werner, F.
登録日2021-06-04
公開日2021-08-25
最終更新日2024-07-17
実験手法ELECTRON MICROSCOPY (2.61 Å)
主引用文献Structural basis of RNA polymerase inhibition by viral and host factors.
Nat Commun, 12, 2021
8G9U
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BU of 8g9u by Molmil
Exploiting Activation and Inactivation Mechanisms in Type I-C CRISPR-Cas3 for Genome Editing Applications
分子名称: CRISPR-associated protein, Csd1 family, Csd2 family, ...
著者Hu, C, Nam, K.H, Ke, A.
登録日2023-02-22
公開日2024-03-06
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Exploiting activation and inactivation mechanisms in type I-C CRISPR-Cas3 for genome-editing applications.
Mol.Cell, 84, 2024
8GAN
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BU of 8gan by Molmil
Exploiting Activation and Inactivation Mechanisms in Type I-C CRISPR-Cas3 for Genome Editing Applications
分子名称: Cas11, Cas5, Cas7, ...
著者Hu, C, Nam, K.H, Ke, A.
登録日2023-02-23
公開日2024-03-06
実験手法ELECTRON MICROSCOPY (3.26 Å)
主引用文献Exploiting activation and inactivation mechanisms in type I-C CRISPR-Cas3 for genome-editing applications.
Mol.Cell, 84, 2024
7NKY
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BU of 7nky by Molmil
RNA Polymerase II-Spt4/5-nucleosome-FACT structure
分子名称: Chromatin elongation factor SPT4, DNA (138-MER), DNA (148-MER), ...
著者Farnung, L, Ochmann, M, Engeholm, M, Cramer, P.
登録日2021-02-19
公開日2021-07-07
最終更新日2024-07-10
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Structural basis of nucleosome transcription mediated by Chd1 and FACT.
Nat.Struct.Mol.Biol., 28, 2021
6XH7
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BU of 6xh7 by Molmil
CueR-TAC without RNA
分子名称: COPPER (II) ION, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ...
著者Liu, B, Shi, W, Yang, Y.
登録日2020-06-18
公開日2021-04-14
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (3.9 Å)
主引用文献Structural basis of copper-efflux-regulator-dependent transcription activation.
Iscience, 24, 2021
6XH8
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CueR-transcription activation complex with RNA transcript
分子名称: COPPER (II) ION, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ...
著者Liu, B, Shi, W, Yang, Y.
登録日2020-06-18
公開日2021-04-14
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (4.1 Å)
主引用文献Structural basis of copper-efflux-regulator-dependent transcription activation.
Iscience, 24, 2021
7NKX
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RNA polymerase II-Spt4/5-nucleosome-Chd1 structure
分子名称: ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, Chromatin elongation factor SPT4, ...
著者Farnung, L, Ochmann, M, Engeholm, M, Cramer, P.
登録日2021-02-19
公開日2021-08-25
最終更新日2024-07-10
実験手法ELECTRON MICROSCOPY (2.9 Å)
主引用文献Structural basis of nucleosome transcription mediated by Chd1 and FACT.
Nat.Struct.Mol.Biol., 28, 2021
7CRE
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BU of 7cre by Molmil
hnRNPK KH3 domain in complex with a ssDNA fragment from the SIRLOIN element
分子名称: Heterogeneous nuclear ribonucleoprotein K, SODIUM ION, ssDNA fragment
著者Yao, J, Sun, Q.
登録日2020-08-13
公開日2021-12-15
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Nuclear import receptors and hnRNPK mediates nuclear import and stress granule localization of SIRLOIN.
Cell.Mol.Life Sci., 78, 2021

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