4UN8
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![BU of 4un8 by Molmil](/molmil-images/mine/4un8) | THE CRYSTAL STRUCTURE OF I-DMOI IN COMPLEX WITH ITS TARGET DNA AT 1H INCUBATION IN 5MM MN (STATE 2) | 分子名称: | 25MER, HOMING ENDONUCLEASE I-DMOI, MANGANESE (II) ION | 著者 | Molina, R, Stella, S, Redondo, P, Gomez, H, Marcaida, M.J, Orozco, M, Prieto, J, Montoya, G. | 登録日 | 2014-05-26 | 公開日 | 2014-12-17 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Visualizing Phosphodiester-Bond Hydrolysis by an Endonuclease. Nat.Struct.Mol.Biol., 22, 2015
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3LLR
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![BU of 3llr by Molmil](/molmil-images/mine/3llr) | Crystal structure of the PWWP domain of Human DNA (cytosine-5-)-methyltransferase 3 alpha | 分子名称: | 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, DNA (cytosine-5)-methyltransferase 3A, SULFATE ION | 著者 | Qiu, W, Dombrovski, L, Ni, S, Weigelt, J, Boutra, C, Arrowsmith, C.H, Edwards, A.M, Min, J, Wu, H, Structural Genomics Consortium (SGC) | 登録日 | 2010-01-29 | 公開日 | 2010-03-23 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Structural and histone binding ability characterizations of human PWWP domains. Plos One, 6, 2011
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3LJA
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![BU of 3lja by Molmil](/molmil-images/mine/3lja) | |
6XRE
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![BU of 6xre by Molmil](/molmil-images/mine/6xre) | Structure of the p53/RNA polymerase II assembly | 分子名称: | Cellular tumor antigen p53, DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11-a, ... | 著者 | Liou, S.-H, Singh, S, Singer, R.H, Coleman, R.A, Liu, W. | 登録日 | 2020-07-12 | 公開日 | 2021-03-24 | 最終更新日 | 2024-03-06 | 実験手法 | ELECTRON MICROSCOPY (4.6 Å) | 主引用文献 | Structure of the p53/RNA polymerase II assembly. Commun Biol, 4, 2021
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6O9L
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![BU of 6o9l by Molmil](/molmil-images/mine/6o9l) | Human holo-PIC in the closed state | 分子名称: | CDK-activating kinase assembly factor MAT1, Cyclin-H, Cyclin-dependent kinase 7, ... | 著者 | Yan, C.L, Dodd, T, He, Y, Tainer, J.A, Tsutakawa, S.E, Ivanov, I. | 登録日 | 2019-03-14 | 公開日 | 2019-05-29 | 最終更新日 | 2024-03-13 | 実験手法 | ELECTRON MICROSCOPY (7.2 Å) | 主引用文献 | Transcription preinitiation complex structure and dynamics provide insight into genetic diseases. Nat.Struct.Mol.Biol., 26, 2019
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3UMZ
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![BU of 3umz by Molmil](/molmil-images/mine/3umz) | Crystal Structure of the human MDC1 FHA Domain | 分子名称: | Mediator of DNA damage checkpoint protein 1 | 著者 | Luo, S, Ye, K. | 登録日 | 2011-11-15 | 公開日 | 2012-01-25 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | 主引用文献 | Structural mechanism of the phosphorylation-dependent dimerization of the MDC1 forkhead-associated domain Nucleic Acids Res., 40, 2012
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2G8I
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![BU of 2g8i by Molmil](/molmil-images/mine/2g8i) | |
2G8W
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![BU of 2g8w by Molmil](/molmil-images/mine/2g8w) | |
5LB3
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![BU of 5lb3 by Molmil](/molmil-images/mine/5lb3) | Crystal structure of human RECQL5 helicase in complex with ADP/Mg. | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ATP-dependent DNA helicase Q5, MAGNESIUM ION, ... | 著者 | Newman, J.A, Aitkenhead, H, Savitsky, P, Krojer, T, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Gileadi, O, Structural Genomics Consortium (SGC) | 登録日 | 2016-06-15 | 公開日 | 2016-07-06 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Insights into the RecQ helicase mechanism revealed by the structure of the helicase domain of human RECQL5. Nucleic Acids Res., 45, 2017
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2G8V
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![BU of 2g8v by Molmil](/molmil-images/mine/2g8v) | |
2G8K
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![BU of 2g8k by Molmil](/molmil-images/mine/2g8k) | |
2G8H
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5LB8
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![BU of 5lb8 by Molmil](/molmil-images/mine/5lb8) | Crystal structure of human RECQL5 helicase APO form. | 分子名称: | ATP-dependent DNA helicase Q5, ZINC ION | 著者 | Newman, J.A, Aitkenhead, H, Savitsky, P, Krojer, T, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Gileadi, O, Structural Genomics Consortium (SGC) | 登録日 | 2016-06-15 | 公開日 | 2016-07-06 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (3.4 Å) | 主引用文献 | Insights into the RecQ helicase mechanism revealed by the structure of the helicase domain of human RECQL5. Nucleic Acids Res., 45, 2017
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5LB5
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![BU of 5lb5 by Molmil](/molmil-images/mine/5lb5) | Crystal structure of human RECQL5 helicase in complex with ADP/Mg (tricilinc form). | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ATP-dependent DNA helicase Q5, DIMETHYL SULFOXIDE, ... | 著者 | Newman, J.A, Aitkenhead, H, Savitsky, P, Krojer, T, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Gileadi, O, Structural Genomics Consortium (SGC) | 登録日 | 2016-06-15 | 公開日 | 2016-07-06 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Insights into the RecQ helicase mechanism revealed by the structure of the helicase domain of human RECQL5. Nucleic Acids Res., 45, 2017
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1HKQ
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![BU of 1hkq by Molmil](/molmil-images/mine/1hkq) | PPS10 plasmid DNA replication initiator protein RepA. Replication inactive, dimeric N-terminal domain. | 分子名称: | BENZOIC ACID, MERCURY (II) ION, PHOSPHATE ION, ... | 著者 | Giraldo, R, Fernandez-Tornero, C, Evans, P.R, Diaz-Orejas, R, Romero, A. | 登録日 | 2003-03-11 | 公開日 | 2003-05-29 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2.75 Å) | 主引用文献 | A Conformational Switch between Transcriptional Repression and Replication Initiation in Repa Dimerization Domain Nat.Struct.Biol., 10, 2003
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2G8F
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2G8U
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![BU of 2g8u by Molmil](/molmil-images/mine/2g8u) | |
7OQY
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![BU of 7oqy by Molmil](/molmil-images/mine/7oqy) | Cryo-EM structure of the cellular negative regulator TFS4 bound to the archaeal RNA polymerase | 分子名称: | Conserved protein, DNA-directed RNA polymerase subunit A', DNA-directed RNA polymerase subunit A'', ... | 著者 | Pilotto, S, Fouqueau, T, Lukoyanova, N, Sheppard, C, Lucas-Staat, S, Diaz-Santin, L.M, Matelska, D, Prangishvili, D, Cheung, A.C.M, Werner, F. | 登録日 | 2021-06-04 | 公開日 | 2021-08-25 | 最終更新日 | 2024-07-17 | 実験手法 | ELECTRON MICROSCOPY (2.61 Å) | 主引用文献 | Structural basis of RNA polymerase inhibition by viral and host factors. Nat Commun, 12, 2021
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8G9U
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![BU of 8g9u by Molmil](/molmil-images/mine/8g9u) | Exploiting Activation and Inactivation Mechanisms in Type I-C CRISPR-Cas3 for Genome Editing Applications | 分子名称: | CRISPR-associated protein, Csd1 family, Csd2 family, ... | 著者 | Hu, C, Nam, K.H, Ke, A. | 登録日 | 2023-02-22 | 公開日 | 2024-03-06 | 実験手法 | ELECTRON MICROSCOPY (3 Å) | 主引用文献 | Exploiting activation and inactivation mechanisms in type I-C CRISPR-Cas3 for genome-editing applications. Mol.Cell, 84, 2024
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8GAN
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![BU of 8gan by Molmil](/molmil-images/mine/8gan) | Exploiting Activation and Inactivation Mechanisms in Type I-C CRISPR-Cas3 for Genome Editing Applications | 分子名称: | Cas11, Cas5, Cas7, ... | 著者 | Hu, C, Nam, K.H, Ke, A. | 登録日 | 2023-02-23 | 公開日 | 2024-03-06 | 実験手法 | ELECTRON MICROSCOPY (3.26 Å) | 主引用文献 | Exploiting activation and inactivation mechanisms in type I-C CRISPR-Cas3 for genome-editing applications. Mol.Cell, 84, 2024
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7NKY
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![BU of 7nky by Molmil](/molmil-images/mine/7nky) | RNA Polymerase II-Spt4/5-nucleosome-FACT structure | 分子名称: | Chromatin elongation factor SPT4, DNA (138-MER), DNA (148-MER), ... | 著者 | Farnung, L, Ochmann, M, Engeholm, M, Cramer, P. | 登録日 | 2021-02-19 | 公開日 | 2021-07-07 | 最終更新日 | 2024-07-10 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | Structural basis of nucleosome transcription mediated by Chd1 and FACT. Nat.Struct.Mol.Biol., 28, 2021
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6XH7
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![BU of 6xh7 by Molmil](/molmil-images/mine/6xh7) | CueR-TAC without RNA | 分子名称: | COPPER (II) ION, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... | 著者 | Liu, B, Shi, W, Yang, Y. | 登録日 | 2020-06-18 | 公開日 | 2021-04-14 | 最終更新日 | 2024-03-06 | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | 主引用文献 | Structural basis of copper-efflux-regulator-dependent transcription activation. Iscience, 24, 2021
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6XH8
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![BU of 6xh8 by Molmil](/molmil-images/mine/6xh8) | CueR-transcription activation complex with RNA transcript | 分子名称: | COPPER (II) ION, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... | 著者 | Liu, B, Shi, W, Yang, Y. | 登録日 | 2020-06-18 | 公開日 | 2021-04-14 | 最終更新日 | 2024-03-06 | 実験手法 | ELECTRON MICROSCOPY (4.1 Å) | 主引用文献 | Structural basis of copper-efflux-regulator-dependent transcription activation. Iscience, 24, 2021
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7NKX
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![BU of 7nkx by Molmil](/molmil-images/mine/7nkx) | RNA polymerase II-Spt4/5-nucleosome-Chd1 structure | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, Chromatin elongation factor SPT4, ... | 著者 | Farnung, L, Ochmann, M, Engeholm, M, Cramer, P. | 登録日 | 2021-02-19 | 公開日 | 2021-08-25 | 最終更新日 | 2024-07-10 | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | 主引用文献 | Structural basis of nucleosome transcription mediated by Chd1 and FACT. Nat.Struct.Mol.Biol., 28, 2021
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7CRE
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![BU of 7cre by Molmil](/molmil-images/mine/7cre) | |