7OQY

Cryo-EM structure of the cellular negative regulator TFS4 bound to the archaeal RNA polymerase

Summary for 7OQY

• Entry DOI: 10.2210/pdb7oqy/pdb
• Related: 7ok0 7oq4
• EMDB information: 12960 13026 13034
• Descriptor: DNA-directed RNA polymerase subunit A', DNA-directed RNA polymerase subunit L, DNA-directed RNA polymerase subunit N, ... (17 entities in total)
• Functional Keywords: negative regulator, inhibitor, archaea, sso tfs4, trancript cleavage factor, transcription
• Biological source: Saccharolobus solfataricus (strain ATCC 35092 / DSM 1617 / JCM 11322 / P2) (Sulfolobus solfataricus); More
• Total number of polymer chains: 14
• Total formula weight: 416527.14

Authors

Pilotto, S.,Fouqueau, T.,Lukoyanova, N.,Sheppard, C.,Lucas-Staat, S.,Diaz-Santin, L.M.,Matelska, D.,Prangishvili, D.,Cheung, A.C.M.,Werner, F. (deposition date: 2021-06-04, release date: 2021-08-25, Last modification date: 2021-11-03)

• Primary citation: Pilotto, S.,Fouqueau, T.,Lukoyanova, N.,Sheppard, C.,Lucas-Staat, S.,Diaz-Santin, L.M.,Matelska, D.,Prangishvili, D.,Cheung, A.C.M.,Werner, F.; Structural basis of RNA polymerase inhibition by viral and host factors.; Nat Commun, 12:5523-5523, 2021; PubMed: 34535646; DOI: 10.1038/s41467-021-25666-5

Experimental method

ELECTRON MICROSCOPY (2.61 Å)