5LB3

Crystal structure of human RECQL5 helicase in complex with ADP/Mg.

Summary for 5LB3

Entry DOI	10.2210/pdb5lb3/pdb
Descriptor	ATP-dependent DNA helicase Q5, ZINC ION, ADENOSINE-5'-DIPHOSPHATE, ... (5 entities in total)
Functional Keywords	helicase, recq, transcription, dna repair, structural genomics, structural genomics consortium, sgc, hydrolase
Biological source	Homo sapiens (Human)
Cellular location	Isoform Beta: Nucleus, nucleoplasm . Isoform Alpha: Cytoplasm . Isoform Gamma: Cytoplasm : O94762
Total number of polymer chains	2
Total formula weight	100108.19
Authors	Newman, J.A.,Aitkenhead, H.,Savitsky, P.,Krojer, T.,von Delft, F.,Arrowsmith, C.H.,Edwards, A.M.,Bountra, C.,Gileadi, O.,Structural Genomics Consortium (SGC) (deposition date: 2016-06-15, release date: 2016-07-06, Last modification date: 2024-01-10)
Primary citation	Newman, J.A.,Aitkenhead, H.,Savitsky, P.,Gileadi, O. Insights into the RecQ helicase mechanism revealed by the structure of the helicase domain of human RECQL5. Nucleic Acids Res., 45:4231-4243, 2017 Cited by PubMed: 28100692 DOI: 10.1093/nar/gkw1362 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.8 Å)

Structure validation