5LB8
Crystal structure of human RECQL5 helicase APO form.
Summary for 5LB8
Entry DOI | 10.2210/pdb5lb8/pdb |
Descriptor | ATP-dependent DNA helicase Q5, ZINC ION (2 entities in total) |
Functional Keywords | helicase, recq, transcription, dna repair, structural genomics, structural genomics consortium, sgc, hydrolase |
Biological source | Homo sapiens (Human) |
Cellular location | Isoform Beta: Nucleus, nucleoplasm . Isoform Alpha: Cytoplasm . Isoform Gamma: Cytoplasm : O94762 |
Total number of polymer chains | 2 |
Total formula weight | 115725.11 |
Authors | Newman, J.A.,Aitkenhead, H.,Savitsky, P.,Krojer, T.,von Delft, F.,Arrowsmith, C.H.,Edwards, A.M.,Bountra, C.,Gileadi, O.,Structural Genomics Consortium (SGC) (deposition date: 2016-06-15, release date: 2016-07-06, Last modification date: 2024-05-08) |
Primary citation | Newman, J.A.,Aitkenhead, H.,Savitsky, P.,Gileadi, O. Insights into the RecQ helicase mechanism revealed by the structure of the helicase domain of human RECQL5. Nucleic Acids Res., 45:4231-4243, 2017 Cited by PubMed: 28100692DOI: 10.1093/nar/gkw1362 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.4 Å) |
Structure validation
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