8GAN
Exploiting Activation and Inactivation Mechanisms in Type I-C CRISPR-Cas3 for Genome Editing Applications
Summary for 8GAN
Entry DOI | 10.2210/pdb8gan/pdb |
EMDB information | 29901 |
Descriptor | Cas7, Cas11, Cas8, ... (8 entities in total) |
Functional Keywords | crispr, type i-c, cascade, anti-crispr, hydrolase-rna-dna complex, hydrolase/rna/dna |
Biological source | Neisseria lactamica More |
Total number of polymer chains | 16 |
Total formula weight | 399279.19 |
Authors | |
Primary citation | Hu, C.,Myers, M.T.,Zhou, X.,Hou, Z.,Lozen, M.L.,Nam, K.H.,Zhang, Y.,Ke, A. Exploiting activation and inactivation mechanisms in type I-C CRISPR-Cas3 for genome-editing applications. Mol.Cell, 84:463-475.e5, 2024 Cited by PubMed: 38242128DOI: 10.1016/j.molcel.2023.12.034 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.26 Å) |
Structure validation
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