5LB5

Crystal structure of human RECQL5 helicase in complex with ADP/Mg (tricilinc form).

Summary for 5LB5

Entry DOI	10.2210/pdb5lb5/pdb
Descriptor	ATP-dependent DNA helicase Q5, ZINC ION, DIMETHYL SULFOXIDE, ... (6 entities in total)
Functional Keywords	helicase, recq, transcription, dna repair, structural genomics, structural genomics consortium, sgc, hydrolase
Biological source	Homo sapiens (Human)
Cellular location	Isoform Beta: Nucleus, nucleoplasm . Isoform Alpha: Cytoplasm . Isoform Gamma: Cytoplasm : O94762
Total number of polymer chains	4
Total formula weight	200450.78
Authors	Newman, J.A.,Aitkenhead, H.,Savitsky, P.,Krojer, T.,von Delft, F.,Arrowsmith, C.H.,Edwards, A.M.,Bountra, C.,Gileadi, O.,Structural Genomics Consortium (SGC) (deposition date: 2016-06-15, release date: 2016-07-06, Last modification date: 2024-01-10)
Primary citation	Newman, J.A.,Aitkenhead, H.,Savitsky, P.,Gileadi, O. Insights into the RecQ helicase mechanism revealed by the structure of the helicase domain of human RECQL5. Nucleic Acids Res., 45:4231-4243, 2017 Cited by PubMed: 28100692 DOI: 10.1093/nar/gkw1362 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2 Å)

Structure validation