PDB: 19260 件ウェブページステータス検索Chemie searchBIRD

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3JC7	Structure of the eukaryotic replicative CMG helicase and pumpjack motion 分子名称: Cell division control protein 45, DNA replication complex GINS protein PSF1, DNA replication complex GINS protein PSF2, ... 著者 Li, H, Bai, L, Yuan, Z, Sun, J, Georgescu, R.E, Liu, J, O'Donnell, M.E. 登録日 2015-11-24 公開日 2016-02-10 最終更新日 2018-07-18 実験手法 ELECTRON MICROSCOPY (4.8 Å) 主引用文献 Structure of the eukaryotic replicative CMG helicase suggests a pumpjack motion for translocation. Nat.Struct.Mol.Biol., 23, 2016
7JM4	IRF Transcription Factor 分子名称: Interferon regulatory factor 4, Interferon-Stimulated Response Elements 著者 Sundararaj, S, Williams, S.J, Casarotto, M.G. 登録日 2020-07-31 公開日 2021-03-24 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.95 Å) 主引用文献 Structural determinants of the IRF4/DNA homodimeric complex. Nucleic Acids Res., 49, 2021
7JX1	E. coli TSase complex with a bi-substrate reaction intermediate analog 分子名称: (2S)-2-({4-[({(6R)-2,4-diamino-5-[(1-{(2R,4S,5R)-4-hydroxy-5-[(phosphonooxy)methyl]tetrahydrofuran-2-yl}-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)methyl]-5,6,7,8-tetrahydropyrido[3,2-d]pyrimidin-6-yl}methyl)amino]benzoyl}amino)pentanedioic acid (non-preferred name), N-(4-{[(2,4-diamino-7,8-dihydropyrido[3,2-d]pyrimidin-6-yl)methyl]amino}benzene-1-carbonyl)-L-glutamic acid, PHOSPHATE ION, ... 著者 Finer-Moore, J, Kholodar, S.A, Stroud, R.M, Kohen, A. 登録日 2020-08-26 公開日 2021-04-21 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.82 Å) 主引用文献 Caught in Action: X-ray Structure of Thymidylate Synthase with Noncovalent Intermediate Analog. Biochemistry, 60, 2021
7JXF	E. coli TSase complex with a bi-substrate reaction intermediate diastereomer analog 分子名称: (2S)-2-({4-[({(6S)-2,4-diamino-5-[(1-{(2R,4S,5R)-4-hydroxy-5-[(phosphonooxy)methyl]tetrahydrofuran-2-yl}-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)methyl]-5,6,7,8-tetrahydropyrido[3,2-d]pyrimidin-6-yl}methyl)amino]benzoyl}amino)pentanedioic acid (non-preferred name), 5-HYDROXYMETHYLURIDINE-2'-DEOXY-5'-MONOPHOSPHATE, N-[4-({[(6S)-2,4-diamino-5,6,7,8-tetrahydropyrido[3,2-d]pyrimidin-6-yl]methyl}amino)benzene-1-carbonyl]-L-glutamic acid, ... 著者 Finer-Moore, J, Kholodar, S.A, Stroud, R.M, Kohen, A, Moliner, V, Swiderek, K. 登録日 2020-08-27 公開日 2021-04-21 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Caught in Action: X-ray Structure of Thymidylate Synthase with Noncovalent Intermediate Analog. Biochemistry, 60, 2021
7L18	Crystal structure of a tandem deletion mutant of rat NADPH-cytochrome P450 reductase 分子名称: FLAVIN MONONUCLEOTIDE, FLAVIN-ADENINE DINUCLEOTIDE, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... 著者 Hubbard, P.A, Xia, C, Shen, A.L, Kim, J.J.K. 登録日 2020-12-14 公開日 2021-01-13 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.542 Å) 主引用文献 Structural and kinetic investigations of the carboxy terminus of NADPH-cytochrome P450 oxidoreductase. Arch.Biochem.Biophys., 701, 2021
7KQ7	Crystal structure of IL21R in complex with an antibody Fab fragment 分子名称: Antibody heavy chain, Antibody light chain, Interleukin-21 receptor 著者 Mosyak, L, Svenson, K. 登録日 2020-11-13 公開日 2021-04-07 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2.203 Å) 主引用文献 Combining random mutagenesis, structure-guided design and next-generation sequencing to mitigate polyreactivity of an anti-IL-21R antibody. Mabs, 13, 2021
7JTQ	Human Complement Factor B Inhibited by a Slow Off-Rate Modified Aptamer of 31 Bases 分子名称: Complement factor B, DNA (32-MER) 著者 Xu, X, Geisbrecht, B.V. 登録日 2020-08-18 公開日 2020-12-09 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (3.5 Å) 主引用文献 Inhibition of the Complement Alternative Pathway by Chemically Modified DNA Aptamers That Bind with Picomolar Affinity to Factor B. J Immunol., 206, 2021
7LEW	Crystal structure of UBE2G2 in complex with the UBE2G2-binding region of AUP1 分子名称: Lipid droplet-regulating VLDL assembly factor AUP1, Ubiquitin-conjugating enzyme E2 G2 著者 Liang, Y.-H, Smith, C.E, Tsai, Y.C, Weissman, A.M, Ji, X. 登録日 2021-01-15 公開日 2021-11-10 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.736 Å) 主引用文献 A structurally conserved site in AUP1 binds the E2 enzyme UBE2G2 and is essential for ER-associated degradation. Plos Biol., 19, 2021
7MFR	Crystal Structure of a Fab fragment bound to peptide GGM 分子名称: Antibody fragment - Heavy Chain of fab, Antibody fragment - Light Chain of fab, GLY-GLY-MET, ... 著者 Sudhamsu, J. 登録日 2021-04-10 公開日 2021-06-16 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.848 Å) 主引用文献 Antibody toolkit reveals N-terminally ubiquitinated substrates of UBE2W. Nat Commun, 12, 2021
7JTN	Human Complement Factor B Inhibited by a Slow Off-Rate Modified Aptamer of 29 Bases 分子名称: Complement factor B, DNA (30-MER) 著者 Xu, X, Geisbrecht, B.V. 登録日 2020-08-18 公開日 2020-12-09 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 Inhibition of the Complement Alternative Pathway by Chemically Modified DNA Aptamers That Bind with Picomolar Affinity to Factor B. J Immunol., 206, 2021
7LKI	The crystal structure of Epitope III of HCV envelop protein E2 in complex with antibody 1H8 分子名称: Epitope III peptide GLY-ALA-PRO-THR-TYR-SER-TRP-GLY, antibody 1H8 heavy chain, antibody 1H8 light chain 著者 Deng, L, Zhang, P. 登録日 2021-02-02 公開日 2021-08-04 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 A conserved epitope III on hepatitis C virus E2 protein has alternate conformations facilitating cell binding or virus neutralization. Proc.Natl.Acad.Sci.USA, 118, 2021
7LKQ	The PilZ(delta107-117)-FimX(GGDEF-EAL) complex from Xanthomonas citri 分子名称: 9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one), FimX(GGDEF-EAL), MAGNESIUM ION, ... 著者 Llontop, E.E, Guzzo, C.R, Farah, C.S. 登録日 2021-02-02 公開日 2021-08-11 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (3.4 Å) 主引用文献 The PilB-PilZ-FimX regulatory complex of the Type IV pilus from Xanthomonas citri. Plos Pathog., 17, 2021
7LKO	The PilB(N-terminal)-PilZ complex of the Type IV pilus from Xanthomonas citri (2.9 A) 分子名称: Pilus biogenesis protein, SULFATE ION, Type IV fimbriae assembly protein 著者 Llontop, E.E, Guzzo, C.R, Farah, C.S. 登録日 2021-02-02 公開日 2021-08-11 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2.88 Å) 主引用文献 The PilB-PilZ-FimX regulatory complex of the Type IV pilus from Xanthomonas citri. Plos Pathog., 17, 2021
7LKN	The PilB(N-terminal_P70S mutant)-PilZ complex (SeMet) 分子名称: Pilus biogenesis protein, SULFATE ION, Type IV fimbriae assembly protein 著者 Llontop, E.E, Guzzo, C.R, Farah, C.S. 登録日 2021-02-02 公開日 2021-08-11 最終更新日 2021-09-01 実験手法 X-RAY DIFFRACTION (1.71 Å) 主引用文献 The PilB-PilZ-FimX regulatory complex of the Type IV pilus from Xanthomonas citri. Plos Pathog., 17, 2021
7LKM	The PilB(N-terminal_P70S mutant)-PilZ complex of the Type IV pilus from Xanthomonas citri 分子名称: Pilus biogenesis protein, SULFATE ION, Type IV fimbriae assembly protein 著者 Llontop, E.E, Guzzo, C.R, Farah, C.S. 登録日 2021-02-02 公開日 2021-08-11 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 The PilB-PilZ-FimX regulatory complex of the Type IV pilus from Xanthomonas citri. Plos Pathog., 17, 2021
3AL2	Crystal Structure of TopBP1 BRCT7/8 分子名称: DNA topoisomerase 2-binding protein 1, SULFATE ION 著者 Leung, C.C, Glover, J.N. 登録日 2010-07-22 公開日 2010-12-01 最終更新日 2017-10-11 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Molecular basis of BACH1/FANCJ recognition by TopBP1 in DNA replication checkpoint control J.Biol.Chem., 286, 2011
3AKJ	Crystal structure of A Helicobacter pylori proinflammatory kinase CtkA 分子名称: CtkA 著者 Kim, D.J, Suh, S.W. 登録日 2010-07-14 公開日 2010-12-01 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Helicobacter pylori proinflammatory protein up-regulates NF-kappaB as a cell-translocating Ser/Thr kinase Proc.Natl.Acad.Sci.USA, 107, 2010
3ANT	Human soluble epoxide hydrolase in complex with a synthetic inhibitor 分子名称: 4-[3-(1-methylethyl)-1,2,4-oxadiazol-5-yl]-N-[(1S,2R)-2-phenylcyclopropyl]piperidine-1-carboxamide, Epoxide hydrolase 2 著者 Chiyo, N, Ishii, T, Hourai, S, Yanagi, K. 登録日 2010-09-08 公開日 2011-01-19 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 A practical use of ligand efficiency indices out of the fragment-based approach: ligand efficiency-guided lead identification of soluble epoxide hydrolase inhibitors J.Med.Chem., 54, 2011
3ANO	Crystal Structure of a Novel Diadenosine 5',5'''-P1,P4-Tetraphosphate Phosphorylase from Mycobacterium tuberculosis H37Rv 分子名称: AP-4-A phosphorylase, PHOSPHATE ION, TETRAETHYLENE GLYCOL 著者 Mori, S, Shibayama, K, Wachino, J, Arakawa, Y. 登録日 2010-09-06 公開日 2011-05-18 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (1.894 Å) 主引用文献 Structural insights into the novel diadenosine 5',5-P1,P4-tetraphosphate phosphorylase from Mycobacterium tuberculosis H37Rv J.Mol.Biol., 410, 2011
3ANS	Human soluble epoxide hydrolase in complex with a synthetic inhibitor 分子名称: 4-cyano-N-[(1S,2R)-2-phenylcyclopropyl]benzamide, Epoxide hydrolase 2 著者 Chiyo, N, Ishii, T, Hourai, S, Yanagi, K. 登録日 2010-09-08 公開日 2011-01-19 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (1.98 Å) 主引用文献 A practical use of ligand efficiency indices out of the fragment-based approach: ligand efficiency-guided lead identification of soluble epoxide hydrolase inhibitors J.Med.Chem., 54, 2011
3AKL	Crystal structure of A Helicobacter pylori proinflammatory kinase CtkA 分子名称: ADENOSINE-5'-DIPHOSPHATE, Ctka, MAGNESIUM ION, ... 著者 Kim, D.J, Suh, S.W. 登録日 2010-07-14 公開日 2010-12-01 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Helicobacter pylori proinflammatory protein up-regulates NF-kappaB as a cell-translocating Ser/Thr kinase Proc.Natl.Acad.Sci.USA, 107, 2010
3AKK	Crystal structure of A Helicobacter pylori proinflammatory kinase CtkA 分子名称: ADENOSINE-5'-DIPHOSPHATE, CtkA, MAGNESIUM ION 著者 Kim, D.J, Suh, S.W. 登録日 2010-07-14 公開日 2010-12-01 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Helicobacter pylori proinflammatory protein up-regulates NF-kappaB as a cell-translocating Ser/Thr kinase Proc.Natl.Acad.Sci.USA, 107, 2010
3AL5	Crystal structure of Human TYW5 分子名称: JmjC domain-containing protein C2orf60, MAGNESIUM ION 著者 Kato, M, Araiso, Y, Ishitani, R, Nureki, O. 登録日 2010-07-26 公開日 2010-11-24 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (2.503 Å) 主引用文献 Crystal structure of a novel JmjC-domain-containing protein, TYW5, involved in tRNA modification. Nucleic Acids Res., 39, 2011
3AOB	Structures of the multidrug exporter AcrB reveal a proximal multisite drug-binding pocket 分子名称: Acriflavine resistance protein B, RIFAMPICIN 著者 Nakashima, R, Sakurai, K, Yamaguchi, A. 登録日 2010-09-23 公開日 2011-11-30 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (3.35 Å) 主引用文献 Structures of the multidrug exporter AcrB reveal a proximal multisite drug-binding pocket Nature, 480, 2011
3AM1	Crystal structure of O-Phosphoseryl-tRNA kinase complexed with anticodon-stem/loop truncated tRNA(Sec) 分子名称: ADENOSINE-5'-TRIPHOSPHATE, ASL-truncated tRNA, L-seryl-tRNA(Sec) kinase, ... 著者 Araiso, Y, Ishitani, R, Nureki, O. 登録日 2010-08-11 公開日 2010-12-29 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 C-terminal domain of archaeal O-phosphoseryl-tRNA kinase displays large-scale motion to bind the 7-bp D-stem of archaeal tRNA(Sec) Nucleic Acids Res., 39, 2011

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