3JC7
Structure of the eukaryotic replicative CMG helicase and pumpjack motion
Summary for 3JC7
Entry DOI | 10.2210/pdb3jc7/pdb |
Related | 3JC5 3JC6 |
EMDB information | 6534 6535 6536 |
Descriptor | DNA replication licensing factor MCM2, DNA replication complex GINS protein PSF1, DNA replication complex GINS protein PSF3, ... (12 entities in total) |
Functional Keywords | cmg helicase, cryo-em, hydrolase |
Biological source | Saccharomyces cerevisiae (yeast) More |
Total number of polymer chains | 11 |
Total formula weight | 785823.29 |
Authors | Li, H.,Bai, L.,Yuan, Z.,Sun, J.,Georgescu, R.E.,Liu, J.,O'Donnell, M.E. (deposition date: 2015-11-24, release date: 2016-02-10, Last modification date: 2018-07-18) |
Primary citation | Yuan, Z.,Bai, L.,Sun, J.,Georgescu, R.,Liu, J.,O'Donnell, M.E.,Li, H. Structure of the eukaryotic replicative CMG helicase suggests a pumpjack motion for translocation. Nat.Struct.Mol.Biol., 23:217-224, 2016 Cited by PubMed: 26854665DOI: 10.1038/nsmb.3170 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (4.8 Å) |
Structure validation
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