3IXS
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3ixs by Molmil](/molmil-images/mine/3ixs) | Ring1B C-terminal domain/RYBP C-terminal domain Complex | 分子名称: | 1,2-ETHANEDIOL, 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, E3 ubiquitin-protein ligase RING2, ... | 著者 | Wang, R, Taylor, A.B, Kim, C.A. | 登録日 | 2009-09-04 | 公開日 | 2010-08-25 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Polycomb Group Targeting through Different Binding Partners of RING1B C-Terminal Domain. Structure, 18, 2010
|
|
4DDI
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4ddi by Molmil](/molmil-images/mine/4ddi) | |
4DDG
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4ddg by Molmil](/molmil-images/mine/4ddg) | |
7R5K
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7r5k by Molmil](/molmil-images/mine/7r5k) | Human nuclear pore complex (constricted) | 分子名称: | Aladin, E3 SUMO-protein ligase RanBP2, Nuclear pore complex protein Nup107, ... | 著者 | Mosalaganti, S, Obarska-Kosinska, A, Siggel, M, Taniguchi, R, Turonova, B, Zimmerli, C.E, Buczak, K, Schmidt, F.H, Margiotta, E, Mackmull, M.T, Hagen, W.J.H, Hummer, G, Kosinski, J, Beck, M. | 登録日 | 2022-02-10 | 公開日 | 2022-06-22 | 最終更新日 | 2024-07-17 | 実験手法 | ELECTRON MICROSCOPY (12 Å) | 主引用文献 | AI-based structure prediction empowers integrative structural analysis of human nuclear pores. Science, 376, 2022
|
|
7R5J
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7r5j by Molmil](/molmil-images/mine/7r5j) | Human nuclear pore complex (dilated) | 分子名称: | Aladin, E3 SUMO-protein ligase RanBP2, Nuclear pore complex protein Nup107, ... | 著者 | Mosalaganti, S, Obarska-Kosinska, A, Siggel, M, Taniguchi, R, Turonova, B, Zimmerli, C.E, Buczak, K, Schmidt, F.H, Margiotta, E, Mackmull, M.T, Hagen, W.J.H, Hummer, G, Kosinski, J, Beck, M. | 登録日 | 2022-02-10 | 公開日 | 2022-09-21 | 最終更新日 | 2024-07-17 | 実験手法 | ELECTRON MICROSCOPY (50 Å) | 主引用文献 | AI-based structure prediction empowers integrative structural analysis of human nuclear pores Science, 376, 2022
|
|
5NGZ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5ngz by Molmil](/molmil-images/mine/5ngz) | Ube2T in complex with fragment EM04 | 分子名称: | 1-(1,3-benzothiazol-2-yl)methanamine, Ubiquitin-conjugating enzyme E2 T | 著者 | Morreale, F.E, Bortoluzzi, A, Chaugule, V.K, Arkinson, C, Walden, H, Ciulli, A. | 登録日 | 2017-03-21 | 公開日 | 2017-05-03 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Allosteric Targeting of the Fanconi Anemia Ubiquitin-Conjugating Enzyme Ube2T by Fragment Screening. J. Med. Chem., 60, 2017
|
|
5MGV
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5mgv by Molmil](/molmil-images/mine/5mgv) | Kinetic and Structural Changes in HsmtPheRS, Induced by Pathogenic Mutations in Human FARS2 | 分子名称: | Phenylalanine--tRNA ligase, mitochondrial | 著者 | Kartvelishvili, E, Tworowski, D, Vernon, H, Chrzanowska-Lightowlers, Z, Moor, N, Wang, J, Wong, L.-J, Safro, M. | 登録日 | 2016-11-22 | 公開日 | 2017-05-03 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | 主引用文献 | Kinetic and structural changes in HsmtPheRS, induced by pathogenic mutations in human FARS2. Protein Sci., 26, 2017
|
|
5JH5
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5jh5 by Molmil](/molmil-images/mine/5jh5) | Structural Basis for the Hierarchical Assembly of the Core of PRC1.1 | 分子名称: | BCL-6 corepressor-like protein 1, Lysine-specific demethylase 2B, Polycomb group RING finger protein 1, ... | 著者 | Wong, S.J, Taylor, A.B, Hart, P.J, Kim, C.A. | 登録日 | 2016-04-20 | 公開日 | 2016-09-14 | 最終更新日 | 2016-10-19 | 実験手法 | X-RAY DIFFRACTION (2.55 Å) | 主引用文献 | KDM2B Recruitment of the Polycomb Group Complex, PRC1.1, Requires Cooperation between PCGF1 and BCORL1. Structure, 24, 2016
|
|
6NIF
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6nif by Molmil](/molmil-images/mine/6nif) | crystal structure of human REV7-RAN complex | 分子名称: | hREV7, GTP-binding nuclear protein Ran, hREV3 fusion | 著者 | Wang, X, Pertz, L, Hua, D.P, Zhang, T.Q, Listovsky, T, Xie, W. | 登録日 | 2018-12-27 | 公開日 | 2019-09-11 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.002 Å) | 主引用文献 | REV7 has a dynamic adaptor region to accommodate small GTPase RAN/ShigellaIpaB ligands, and its activity is regulated by the RanGTP/GDP switch. J.Biol.Chem., 294, 2019
|
|
3C6O
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3c6o by Molmil](/molmil-images/mine/3c6o) | |
6DJW
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6djw by Molmil](/molmil-images/mine/6djw) | Crystal Structure of pParkin (REP and RING2 deleted)-pUb-UbcH7 complex | 分子名称: | RBR-type E3 ubiquitin transferase,RBR-type E3 ubiquitin transferase, Ubiquitin, Ubiquitin-conjugating enzyme E2 L3, ... | 著者 | Sauve, V, Sung, G, Trempe, J.F, Gehring, K. | 登録日 | 2018-05-26 | 公開日 | 2018-07-04 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (3.801 Å) | 主引用文献 | Mechanism of parkin activation by phosphorylation. Nat. Struct. Mol. Biol., 25, 2018
|
|
6HCF
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6hcf by Molmil](/molmil-images/mine/6hcf) | Structure of the rabbit 80S ribosome stalled on globin mRNA at the stop codon | 分子名称: | 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S12, ... | 著者 | Juszkiewicz, S, Chandrasekaran, V, Lin, Z, Kraatz, S, Ramakrishnan, V, Hegde, R.S. | 登録日 | 2018-08-14 | 公開日 | 2018-10-17 | 最終更新日 | 2024-05-15 | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | 主引用文献 | ZNF598 Is a Quality Control Sensor of Collided Ribosomes. Mol. Cell, 72, 2018
|
|
6HCM
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6hcm by Molmil](/molmil-images/mine/6hcm) | Structure of the rabbit collided di-ribosome (stalled monosome) | 分子名称: | 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S12, ... | 著者 | Juszkiewicz, S, Chandrasekaran, V, Lin, Z, Kraatz, S, Ramakrishnan, V, Hegde, R.S. | 登録日 | 2018-08-15 | 公開日 | 2018-10-17 | 最終更新日 | 2024-05-15 | 実験手法 | ELECTRON MICROSCOPY (6.8 Å) | 主引用文献 | ZNF598 Is a Quality Control Sensor of Collided Ribosomes. Mol. Cell, 72, 2018
|
|
3C6N
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3c6n by Molmil](/molmil-images/mine/3c6n) | Small molecule agonists and antagonists of F-box protein-substrate interactions in auxin perception and signaling | 分子名称: | (2S)-8-[(tert-butoxycarbonyl)amino]-2-(1H-indol-3-yl)octanoic acid, INOSITOL HEXAKISPHOSPHATE, SKP1-like protein 1A, ... | 著者 | Tan, X, Zheng, N, Hayashi, K. | 登録日 | 2008-02-04 | 公開日 | 2008-04-22 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Small-molecule agonists and antagonists of F-box protein-substrate interactions in auxin perception and signaling. Proc.Natl.Acad.Sci.Usa, 105, 2008
|
|
6HCJ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6hcj by Molmil](/molmil-images/mine/6hcj) | Structure of the rabbit 80S ribosome on globin mRNA in the rotated state with A/P and P/E tRNAs | 分子名称: | 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S12, ... | 著者 | Juszkiewicz, S, Chandrasekaran, V, Lin, Z, Kraatz, S, Ramakrishnan, V, Hegde, R.S. | 登録日 | 2018-08-15 | 公開日 | 2018-10-17 | 最終更新日 | 2018-11-14 | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | 主引用文献 | ZNF598 Is a Quality Control Sensor of Collided Ribosomes. Mol. Cell, 72, 2018
|
|
6HCQ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6hcq by Molmil](/molmil-images/mine/6hcq) | Structure of the rabbit collided di-ribosome (collided monosome) | 分子名称: | 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S12, ... | 著者 | Juszkiewicz, S, Chandrasekaran, V, Lin, Z, Kraatz, S, Ramakrishnan, V, Hegde, R.S. | 登録日 | 2018-08-16 | 公開日 | 2018-10-17 | 最終更新日 | 2018-11-14 | 実験手法 | ELECTRON MICROSCOPY (6.5 Å) | 主引用文献 | ZNF598 Is a Quality Control Sensor of Collided Ribosomes. Mol. Cell, 72, 2018
|
|
3C6P
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3c6p by Molmil](/molmil-images/mine/3c6p) | |
6DJX
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6djx by Molmil](/molmil-images/mine/6djx) | Crystal Structure of pParkin-pUb-UbcH7 complex | 分子名称: | RBR-type E3 ubiquitin transferase,RBR-type E3 ubiquitin transferase, Ubiquitin, Ubiquitin-conjugating enzyme E2 L3, ... | 著者 | Sauve, V, Sung, G, Trempe, J.F, Gehring, K. | 登録日 | 2018-05-27 | 公開日 | 2018-07-04 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (4.801 Å) | 主引用文献 | Mechanism of parkin activation by phosphorylation. Nat. Struct. Mol. Biol., 25, 2018
|
|
1XO0
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1xo0 by Molmil](/molmil-images/mine/1xo0) | High resolution structure of the holliday junction intermediate in cre-loxp site-specific recombination | 分子名称: | Recombinase CRE, loxP | 著者 | Ghosh, K, Lau, C.K, Guo, F, Segall, A.M, Van Duyne, G.D. | 登録日 | 2004-10-05 | 公開日 | 2004-12-14 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Peptide trapping of the Holliday junction intermediate in Cre-loxP site-specific recombination. J.Biol.Chem., 280, 2005
|
|
4QDI
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4qdi by Molmil](/molmil-images/mine/4qdi) | Crystal structure II of MurF from Acinetobacter baumannii | 分子名称: | 1,2-ETHANEDIOL, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | 著者 | An, Y.J, Jeong, C.S, Cha, S.S. | 登録日 | 2014-05-13 | 公開日 | 2015-04-01 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | ATP-binding mode including a carbamoylated lysine and two Mg(2+) ions, and substrate-binding mode in Acinetobacter baumannii MurF Biochem.Biophys.Res.Commun., 450, 2014
|
|
1GGM
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1ggm by Molmil](/molmil-images/mine/1ggm) | |
7BBF
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7bbf by Molmil](/molmil-images/mine/7bbf) | |
7L9P
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7l9p by Molmil](/molmil-images/mine/7l9p) | Structure of human SHLD2-SHLD3-REV7-TRIP13(E253Q) complex | 分子名称: | Mitotic spindle assembly checkpoint protein MAD2B, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, Pachytene checkpoint protein 2 homolog, ... | 著者 | Xie, W, Patel, D.J. | 登録日 | 2021-01-04 | 公開日 | 2021-03-03 | 最終更新日 | 2024-03-06 | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | 主引用文献 | Molecular mechanisms of assembly and TRIP13-mediated remodeling of the human Shieldin complex. Proc.Natl.Acad.Sci.USA, 118, 2021
|
|
7JTP
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7jtp by Molmil](/molmil-images/mine/7jtp) | Crystal structure of Protac MS67 in complex with the WD repeat-containing protein 5 and pVHL:ElonginC:ElonginB | 分子名称: | Elongin-B, Elongin-C, GLYCEROL, ... | 著者 | Kottur, J, Jain, R, Aggarwal, A.K. | 登録日 | 2020-08-18 | 公開日 | 2021-10-06 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.12 Å) | 主引用文献 | A selective WDR5 degrader inhibits acute myeloid leukemia in patient-derived mouse models. Sci Transl Med, 13, 2021
|
|
7JTO
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7jto by Molmil](/molmil-images/mine/7jto) | Crystal structure of Protac MS33 in complex with the WD repeat-containing protein 5 and pVHL:ElonginC:ElonginB | 分子名称: | 1,2-ETHANEDIOL, 3-methyl-N-(11-{[2-(4-{[4'-(4-methylpiperazin-1-yl)-3'-{[6-oxo-4-(trifluoromethyl)-5,6-dihydropyridine-3-carbonyl]amino}[1,1'-biphenyl]-3-yl]methyl}piperazin-1-yl)ethyl]amino}-11-oxoundecanoyl)-L-valyl-(4R)-4-hydroxy-N-{[4-(4-methyl-1,3-thiazol-5-yl)phenyl]methyl}-L-prolinamide, Elongin-B, ... | 著者 | Kottur, J, Jain, R, Aggarwal, A.K. | 登録日 | 2020-08-18 | 公開日 | 2021-10-06 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | A selective WDR5 degrader inhibits acute myeloid leukemia in patient-derived mouse models. Sci Transl Med, 13, 2021
|
|