5JH5

Structural Basis for the Hierarchical Assembly of the Core of PRC1.1

Summary for 5JH5

Entry DOI	10.2210/pdb5jh5/pdb
Descriptor	Lysine-specific demethylase 2B, S-phase kinase-associated protein 1, Polycomb group RING finger protein 1, ... (5 entities in total)
Functional Keywords	gene repression, complex, transcription regulation, transcription repressor, metal binding protein-transcription complex, metal binding protein/transcription
Biological source	Homo sapiens (Human) More
Cellular location	Nucleus, nucleolus : Q8NHM5 Nucleus : Q9BSM1 Q5H9F3
Total number of polymer chains	4
Total formula weight	78554.55
Authors	Wong, S.J.,Taylor, A.B.,Hart, P.J.,Kim, C.A. (deposition date: 2016-04-20, release date: 2016-09-14, Last modification date: 2016-10-19)
Primary citation	Wong, S.J.,Gearhart, M.D.,Taylor, A.B.,Nanyes, D.R.,Ha, D.J.,Robinson, A.K.,Artigas, J.A.,Lee, O.J.,Demeler, B.,Hart, P.J.,Bardwell, V.J.,Kim, C.A. KDM2B Recruitment of the Polycomb Group Complex, PRC1.1, Requires Cooperation between PCGF1 and BCORL1. Structure, 24:1795-1801, 2016 Cited by PubMed: 27568929 DOI: 10.1016/j.str.2016.07.011 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.55 Å)

Structure validation